Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Colin M. Hayman"'
Autor:
Katia Pes, Donato Romanazzi, Thomas T. Wheeler, Cristina Sanchez-Garcia, Johan Svenson, Colin M. Hayman, Leonardo Mata, Marie Magnusson
Publikováno v:
ACS Agricultural Science & Technology. 1:436-442
Autor:
Michael Findlay, Robert Weinkove, Marina Dzhelali, Ian F. Hermans, Graham Caygill, Geoffrey M. Williams, Margaret A. Brimble, Victoria Hinder, Olivier Gasser, Monica McCusker, Gavin F. Painter, Jerome Macapagal, Catherine Wood, P. Rod Dunbar, Catherine Barrow, Brigitta Mester, Evelyn Bauer, Jeremy D. Jones, Katrina Sharples, Colin M. Hayman
Publikováno v:
Cancer Immunology, Immunotherapy. 67:285-298
Vaccines that elicit targeted tumor antigen-specific T-cell responses have the potential to be used as adjuvant therapy in patients with high risk of relapse. However, the responses induced by vaccines in cancer patients have generally been disappoin
Autor:
Ian F. Hermans, Dale I. Godfrey, Benjamin J. Compton, Hui-Fern Koay, Stephen J. Turner, Catarina F. Almeida, Taryn L. Osmond, Katherine Kedzierska, Jasmine Li, Margaret A. Brimble, Kathryn J. Farrand, Geoffrey M. Williams, Lukasz Kedzierski, Lauren R. Holz, Marios Koutsakos, Ching Wen Tang, Gavin F. Painter, Colin M. Hayman, Zhongfang Wang, Regan J. Anderson
Publikováno v:
ACS Chemical Biology. 12:2898-2905
The development of a universal vaccine for influenza A virus (IAV) that does not require seasonal modification is a long-standing health goal, particularly in the context of the increasing threat of new global pandemics. Vaccines that specifically in
Autor:
Dirk M. Zajonc, Robert Weinkove, Mary Speir, Ian F. Hermans, Peter M. Ferguson, Jing Wang, Colin M. Hayman, Taryn L. Osmond, Leonid S. Metelitsa, Gavin F. Painter, Collin Brooks, Dale I. Godfrey, Lin-Kin Yong, Margaret A. Brimble, Ching Wen Tang, Geoffrey M. Williams, Olivier Gasser, Susanna T. S. Chan, Benjamin J. Compton, Regan J. Anderson, Kathryn J. Farrand, Taylor R. Cooney, Astrid Authier-Hall
Publikováno v:
Organicbiomolecular chemistry. 17(5)
Activated NKT cells can stimulate antigen-presenting cells leading to enhanced peptide antigen-specific immunity. However, administration of potent NKT cell agonists like α-galactosylceramide (α-GalCer) can be associated with release of high levels
Autor:
Ian F. Hermans, Taryn L. Osmond, Gavin F. Painter, Benjamin J. Compton, Colin M. Hayman, Ching-Wen Tang, Karen A. Johnston, David S. Larsen
Publikováno v:
Organic Letters. 17:5954-5957
A major challenge in the development of highly defined synthetic vaccines is the codelivery of vaccine components (i.e., antigen and adjuvant) to secondary lymphoid tissue to induce optimal immune responses. This problem can be addressed by synthesiz
Publikováno v:
Coupling and Decoupling of Diverse Molecular Units in Glycosciences ISBN: 9783319655864
Through vaccination infectious diseases such as smallpox, polio, measles, and tetanus have either been eradicated or significantly restricted. However, there remain many diseases for which no effective vaccine exists, and therefore new vaccine approa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a69d59ae825f8a931be1db57f819822
https://doi.org/10.1007/978-3-319-65587-1_14
https://doi.org/10.1007/978-3-319-65587-1_14
Autor:
Paul W. R. Harris, Benjamin J. Compton, Renata Kowalczyk, Gene W. Swinerd, Margaret A. Brimble, Ching-Wen Tang, Olivier Gasser, Colin M. Hayman, Robert Weinkove, Ian F. Hermans, Gavin F. Painter, Astrid Authier-Hall, Regan J. Anderson, David S. Larsen
Publikováno v:
Chemical Science
Glycolipid–peptide conjugates designed to release vaccine components within target cells ensuring potent CD1d dependent T cell responses.
It is known that T cells can eliminate tumour cells through recognition of unique or aberrantly expressed
It is known that T cells can eliminate tumour cells through recognition of unique or aberrantly expressed
Autor:
Thomas Rades, Benjamin J. Compton, David S. Larsen, Madlen Hubert, Gavin F. Painter, Sarah Hook, Colin M. Hayman
Publikováno v:
Molecular Pharmaceutics. 10:1928-1939
Native phosphatidylinositol mannosides (PIMs), isolated from the cell wall of Mycobacterium bovis, and synthetic PIM analogues have been reported to offer a variety of immunomodulating properties, including both suppressive and stimulatory activity.
Autor:
William John Martin, Steven M. Toms, Benjamin J. Compton, Gary D. Ainge, Gavin F. Painter, Colin M. Hayman, Jacquie L. Harper, David S. Larsen
Publikováno v:
The Journal of Organic Chemistry. 76:4941-4951
Phosphatidylinositol mannosides (PIMs) isolated from mycobacteria have been identified as an important class of phosphoglycolipids with significant immune-modulating properties. We present here the synthesis of dipalmitoyl phosphatidylinositol hexama
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:917-925
Two approaches for the synthesis of a phosphatidylinositol dimannoside (PIM₂) analogue 4 that mimics the suppressive activity of natural PIMs and also synthetic PIM₂ have been developed. This analogue, where the inositol core was replaced by glyc