Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Colin M Stack"'
Autor:
Jonathan Lowther, Mark W Robinson, Sheila M Donnelly, Weibo Xu, Colin M Stack, Jacqueline M Matthews, John P Dalton
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 3, Iss 1, p e369 (2009)
The helminth parasite Fasciola hepatica secretes cathepsin L cysteine proteases to invade its host, migrate through tissues and digest haemoglobin, its main source of amino acids. Here we investigated the importance of pH in regulating the activity a
Externí odkaz:
https://doaj.org/article/50ca6e8f1bc54096ae780fbbc94fd6ae
Autor:
Moufid El-Khoury, Rogine Ligot, Simon Mahoney, Colin M. Stack, Gabriel G. Perrone, C. Oliver Morton
Publikováno v:
BMC Research Notes, Vol 10, Iss 1, Pp 1-6 (2017)
Abstract Objective Recent studies into the antifungal activity of NK-cells against the Aspergillus fumigatus have presented differing accounts on their mode of antifungal activity. One of these mechanisms proposed that NK-cells may kill the fungus vi
Externí odkaz:
https://doaj.org/article/54f85b4bb5b14f48b59974a64255c03f
Autor:
Colin M. Stack, C. Oliver Morton
Publikováno v:
Current Fungal Infection Reports. 15:127-135
This review examined the literature on the diagnosis of invasive fungal disease (IFD) in patients undergoing solid organ transplants (SOT) to describe the diagnostic options available for this cohort. The tools available for the diagnosis of IFD in S
Publikováno v:
Experimental Parasitology. 157:68-77
The ability for protozoan parasites to tolerate pH fluctuations within their niche is critical for the establishment of infection and require the parasite to be capable of adapting to a distinct pH range. We used two host adapted Tritrichomonas foetu
Autor:
Gabriel G. Perrone, Rogine Ligot, Moufid El-Khoury, C. Oliver Morton, Simon Mahoney, Colin M. Stack
Publikováno v:
BMC Research Notes
BMC Research Notes, Vol 10, Iss 1, Pp 1-6 (2017)
BMC Research Notes, Vol 10, Iss 1, Pp 1-6 (2017)
Objective Recent studies into the antifungal activity of NK-cells against the Aspergillus fumigatus have presented differing accounts on their mode of antifungal activity. One of these mechanisms proposed that NK-cells may kill the fungus via the dir
Autor:
George Tsiotsioras, Colin M. Stack, Matthew P. Padula, Jens R. Coorssen, Jan Šlapeta, Leah J. Stroud, Dylan Druery
© 2017 Australian Society for Parasitology Certain clinical isolates of Tritrichomonas foetus infect the urogenital tract of cattle while others infect the gastrointestinal tract of cats. Previous studies have identified subtle genetic differences b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6515c9ec36bbb6838d11c1d257cfeba5
https://hdl.handle.net/10453/109353
https://hdl.handle.net/10453/109353
Autor:
Colin M. Stack, Fabio L. da Silva, Malcolm K. Jones, Erica Lovas, Tina S. Skinner-Adams, Donald L. Gardiner, Elena Taran, John P. Dalton, Franka Teuscher, Christopher L. Brown, Matthew W. A. Dixon, Katharine R. Trenholme, Leann Tilley
Publikováno v:
Experimental parasitology. 169
Infection with the apicomplexan parasite Plasmodium falciparum is a major cause of morbidity and mortality worldwide. One of the striking features of this parasite is its ability to remodel and decrease the deformability of host red blood cells, a pr
Autor:
Michelle C. Moffitt, Antonio Lauto, Damia Mawad, Leah J. Cronin, Oliver C. Morton, Colin M. Stack
Publikováno v:
Journal of Biophotonics. 7:410-417
Onychomycosis, a fungal infection of the finger or toenails, is predominantly caused by Trichophyton rubrum. Treatment is difficult due to high recurrence rates and problems with treatment compliance. For these reasons, alternative therapies are need
Autor:
Sheila Donnelly, Olwen Golden, C. Read, John P. Dalton, Grace Mulcahy, Colin M. Stack, Mary Sekiya, Robin J. Flynn
Publikováno v:
Vaccine. 28:5551-5557
The liver fluke, Fasciola hepatica causes liver fluke disease, or fasciolosis, in ruminants such as cattle and sheep. An effective vaccine against the helminth parasite is essential to reduce our reliance on anthelmintics, particularly in light of fr
Autor:
Jonathan Lowther, Colin M. Stack, Tina S. Skinner-Adams, Artur Mucha, Katharine R. Trenholme, Marcin Drag, Donald L. Gardiner, John P. Dalton, Sheena McGowan, Christopher L. Brown, Paweł Kafarski, James C. Whisstock, Jolanta Grembecka
Publikováno v:
Trends in Biochemical Sciences. 35:53-61
The neutral aminopeptidases M1 alanyl aminopeptidase (PfM1AAP) and M17 leucine aminopeptidase (PfM17LAP) of the human malaria parasite Plasmodium falciparum are targets for the development of novel anti-malarial drugs. Although the functions of these