Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Colin M Clay"'
Autor:
Ellane R Cleys, Jennifer L Halleran, Vanessa A Enriquez, Juliano C da Silveira, Rachel C West, Quinton A Winger, Russell V Anthony, Jason E Bruemmer, Colin M Clay, Gerrit J Bouma
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117472 (2015)
Sex steroid hormones regulate developmental programming in many tissues, including programming gene expression during prenatal development. While estradiol is known to regulate placentation, little is known about the role of testosterone and androgen
Externí odkaz:
https://doaj.org/article/193f6c4529754169af08846a7b768ae9
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
Gonadotrope cells of the anterior pituitary are characterized by their ability to mount a cyclical pattern of gonadotropin secretion to regulate gonadal function and fertility. Recent in vitro and in vivo evidence suggests that gonadotropes exhibit d
Externí odkaz:
https://doaj.org/article/6f39f7aacef04ca689e915897f437192
Autor:
Terry M. Nett, Colin M. Clay, Kelly S. Kirkley, Jason E. Bruemmer, Edward L. Squires, Luke A. Sylvester, Brittany Runyan, Christianne Magee
Publikováno v:
Theriogenology. 157:199-209
To more clearly understand the equine gonadotrope response to kisspeptin and gonadotropin releasing hormone (GnRH), peripheral LH and FSH were quantified in diestrous mares after treatment with either equine kisspeptide (eKp-10, 0.5 mg iv), GnRH (25
Autor:
Colin M. Clay, Jesus Alejandro Arreguin-Arevalo, Terry M. Nett, Christianne Magee, Kenneth L. Jones, Dilyara A. Murtazina, Ali Ebrahimpour-Boroojeny, Akash Shrestha, Jennifer A Hicks, Jeremy D. Cantlon, Hamidreza Chitsaz, Kelly S. Kirkley
Publikováno v:
Biol Reprod
Gonadotropes represent approximately 5–15% of the total endocrine cell population in the mammalian anterior pituitary. Therefore, assessing the effects of experimental manipulation on virtually any parameter of gonadotrope biology is difficult to d
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2021)
Frontiers in Endocrinology
Frontiers in Endocrinology
Gonadotropes cells located in the anterior pituitary gland are critical for reproductive fitness. A rapid surge in the serum concentration of luteinizing hormone (LH) secreted by anterior pituitary gonadotropes is essential for stimulating ovulation
Autor:
Gregory C. Amberg, Dilyara A. Murtazina, Ulrich Boehm, Nathan L. Chaplin, An K. Dang, Colin M. Clay
Publikováno v:
Journal of Biological Chemistry. 293:16028-16042
Gonadotropin-releasing hormone (GnRH) stimulation of its eponymous receptor on the surface of endocrine anterior pituitary gonadotrope cells (gonadotropes) initiates multiple signaling cascades that culminate in the secretion of luteinizing and folli
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
Frontiers in Endocrinology
Frontiers in Endocrinology
Gonadotrope cells of the anterior pituitary are characterized by their ability to mount a cyclical pattern of gonadotropin secretion to regulate gonadal function and fertility. Recent in vitro and in vivo evidence suggests that gonadotropes exhibit d
Publikováno v:
Theriogenology. 78:1987-1996
Kisspeptides (KiSS) are a recently discovered family of neuropeptides with a central role in regulating the onset of reproductive function in all animals studied to date. We have established biological and physiological evidence for KiSS signaling in
Publikováno v:
Biology of Reproduction. 85:770-778
Estradiol-17beta (E2) is the major regulator of GnRH receptor (GnRHR) gene expression and number during the periovulatory period; however, the mechanisms underlying E2 regulation of the GNRHR gene remain undefined. Herein, we find that E2 conjugated
Autor:
Chun-Ying Ku, Yoon-Sun Kim, Scott Earley, Aida Ulloa, Miao Zhong, Colin M. Clay, Barbara M. Sanborn, Jeremy D. Cantlon, Albert L. Gonzales
Publikováno v:
Cell Calcium. 46:73-84
Canonical transient receptor potential (TRPC) proteins may play a role in regulating changes in intracellular calcium ([Ca(2+)](i)). Human myometrium expresses TRPC4, TRPC1 and TRPC6 mRNAs in greatest relative abundance. Contributions of TRPC4 to inc