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pro vyhledávání: '"Colin Lazarra"'
Autor:
Adam J. Hartigan, Daisy Lam, Jeffrey Marshall, Bob Gantzer, Kyle Rehberger, Nicole M. Gaudelli, Jenny Olins, Chavonna Xu, Bo Yan, Luis A. Barrera, Conrad Rinaldi, Paty Feliciano, Jeremy Decker, Daniel Haupt, Sarah Smith, S. Haihua Chu, Michael S. Packer, Valerie Winton, Matthew Lee, Tanggis Bohnuud, Ian Slaymaker, Teresa McDonald, Colin Lazarra, Salette Martinez, Manuel Ortega, David A. Born, Alexander Liquori, Giuseppe Ciaramella, Carlo Zambonelli
Publikováno v:
Blood. 138:951-951
Conversion of the pathogenic sickle allele to a naturally occurring, non-pathogenic hemoglobin variant, Hb G-Makassar, represents a long-term and durable treatment strategy for sickle cell disease (SCD). Using our engineered adenine base editor, we a