Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Colin L. Welsh"'
Publikováno v:
Biology, Vol 12, Iss 11, p 1370 (2023)
Cyclic-AMP-dependent protein kinase A (PKA) is a critical enzyme involved in various signaling pathways that plays a crucial role in regulating cellular processes including metabolism, gene transcription, cell proliferation, and differentiation. In t
Externí odkaz:
https://doaj.org/article/666ffd711c7a47e0aeb6f3e42654c08e
Autor:
Pankaj Pandey, Gregory D. Cuny, Hien Vo, Anantha Lakshmi Duddupudi, Colin L Welsh, Robert J. Doerksen
Publikováno v:
The Journal of Organic Chemistry. 85:7549-7557
A metal-free oxidative cyclization of N-Boc-acrylamides with (diacetoxyiodo)benzene in acetic acid produced 5,5-disubstituted oxazolidine-2,4-diones with the formation of a C-O bond in moderate to excellent yields. In addition, the reaction was diast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adc289f9d208d759c6929917fe95fa72
https://doi.org/10.1021/acs.joc.0c00581
https://doi.org/10.1021/acs.joc.0c00581
Publikováno v:
The Journal of Chemical Physics. 158:081001
Allosteric regulation of proteins continues to be an engaging research topic for the scientific community. Models describing allosteric communication have evolved from focusing on conformation-based descriptors of protein structural changes to apprec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2778b54357d46982eaf9f23cf00b90a
https://doi.org/10.1063/5.0138175
https://doi.org/10.1063/5.0138175
Publikováno v:
Biophysical Journal. 122:32a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d80701826f3aa0206a8c7c76323fa3b5
https://doi.org/10.1016/j.bpj.2022.11.392
https://doi.org/10.1016/j.bpj.2022.11.392
Publikováno v:
Advances in cancer research. 152
Protein Tyrosine Phosphatases reverse cellular signals initiated by growth factors receptors and other tyrosine kinases by dephosphorylating phosphotyrosine on target proteins. The activity of these enzymes is crucial for maintaining cell homeostasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5ca4dc45fd1ced2978036d9bebaa971
https://pubmed.ncbi.nlm.nih.gov/34353440
https://pubmed.ncbi.nlm.nih.gov/34353440
Autor:
Mark T. Hamann, Pankaj Pandey, Clemens Anklin, Yike Zou, Robert J. Doerksen, Bin Wang, Daneel Ferreira, Mitchell A. Avery, James Sims, Frederick A. Valeriote, Michelle Kelly, Colin L Welsh, Robert P. Stone, Xiaojuan Wang
Publikováno v:
Journal of the American Chemical Society. 141:4338-4344
We report here the orchestration of molecular ion networking and a set of computationally assisted structural elucidation approaches in the discovery of a new class of pyrroloiminoquinone alkaloids that possess selective bioactivity against pancreati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a9017057c23f87c40c5c3c2e1662281
https://doi.org/10.1021/jacs.8b11403
https://doi.org/10.1021/jacs.8b11403
Publikováno v:
Advances in Cancer Research ISBN: 9780128241257
Protein Tyrosine Phosphatases reverse cellular signals initiated by growth factors receptors and other tyrosine kinases by dephosphorylating phosphotyrosine on target proteins. The activity of these enzymes is crucial for maintaining cell homeostasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3da200eb452e17748f16432a1d86edd
https://doi.org/10.1016/bs.acr.2021.06.001
https://doi.org/10.1016/bs.acr.2021.06.001
Autor:
Anantha Lakshmi, Duddupudi, Pankaj, Pandey, Hien, Vo, Colin L, Welsh, Robert J, Doerksen, Gregory D, Cuny
Publikováno v:
The Journal of organic chemistry. 85(11)
A metal-free oxidative cyclization of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::78ddc9687016d39c19e98dbb2d12912d
https://pubmed.ncbi.nlm.nih.gov/32392063
https://pubmed.ncbi.nlm.nih.gov/32392063
Autor:
Hong Ma, Mounika P. Aramandla, Serena D. Stoddard, Laurence H. Beck, Maggie M. Palopoli, Colin L. Welsh, Riya M. Patel, Shana V. Stoddard
Publikováno v:
Proteins. 87(2)
The thrombospondin type-1 domain containing 7A (THSD7A) protein is known to be one of the antigens responsible for the autoimmune disorder idiopathic membranous nephropathy. The structure of this antigen is currently unsolved experimentally. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce31be59ee0a55a3fc4ac9b09404a7a0
https://pubmed.ncbi.nlm.nih.gov/30520531
https://pubmed.ncbi.nlm.nih.gov/30520531