Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Colin K. Choi"'
Autor:
Britta Trappmann, Brendon M. Baker, William J. Polacheck, Colin K. Choi, Jason A. Burdick, Christopher S. Chen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
The fabrication of vascularized 3D tissues requires an understanding of how material properties govern endothelial cell invasion into the surrounding matrix. Here the authors integrate a non-swelling synthetic hydrogel with a microfluidic device to s
Externí odkaz:
https://doaj.org/article/335d95b70c154450b481fc790c3be92a
Autor:
William Y. Wang, Alexander T. Pearson, Matthew L. Kutys, Colin K. Choi, Michele A. Wozniak, Brendon M. Baker, Christopher S. Chen
Publikováno v:
APL Bioengineering, Vol 2, Iss 4, Pp 046107-046107-16 (2018)
Physical features of the extracellular matrix (ECM) heavily influence cell migration strategies and efficiency. Migration in and on fibrous ECMs is of significant physiologic importance, but limitations in the ability to experimentally define the dia
Externí odkaz:
https://doaj.org/article/56f268348fae474eb9f5b8221a8f8814
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 2, p e1000688 (2010)
Productive cell migration requires the spatiotemporal coordination of cell adhesion, membrane protrusion, and actomyosin-mediated contraction. Integrins, engaged by the extracellular matrix (ECM), nucleate the formation of adhesive contacts at the ce
Externí odkaz:
https://doaj.org/article/d121f5e5daca4c3f81c081ba92df8aef
Autor:
Caroline Howes, Li Dong, Jeroen Eyckmans, Assad A. Oberai, Colin K. Choi, Christopher S. Chen, Teodelinda Mirabella, Christine Yoon, Sarah C. Stapleton, Jinling Yang, Jessica M. King
Publikováno v:
Molecular Biology of the Cell
Angiogenic sprouting is a critical process involved in vascular network formation within tissues. During sprouting, tip cells and ensuing stalk cells migrate collectively into the extracellular matrix while preserving cell–cell junctions, forming p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faec4f88f058560b6e387ecebb05181c
https://pubmed.ncbi.nlm.nih.gov/31318321
https://pubmed.ncbi.nlm.nih.gov/31318321
Autor:
Colin K. Choi, Michele A. Wozniak, Matthew L. Kutys, Alexander T. Pearson, William Y. Wang, Brendon M. Baker, Christopher S. Chen
Publikováno v:
APL Bioengineering
APL bioengineering, vol 2, iss 4
APL Bioengineering, Vol 2, Iss 4, Pp 046107-046107-16 (2018)
APL bioengineering, vol 2, iss 4
APL Bioengineering, Vol 2, Iss 4, Pp 046107-046107-16 (2018)
Physical features of the extracellular matrix (ECM) heavily influence cell migration strategies and efficiency. Migration in and on fibrous ECMs is of significant physiologic importance, but limitations in the ability to experimentally define the dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247bd5953d1dc3de8f66db26c11b400e
http://europepmc.org/articles/PMC6481732
http://europepmc.org/articles/PMC6481732
Autor:
William J. Polacheck, Britta Trappmann, Jason A. Burdick, Christopher S. Chen, Colin K. Choi, Brendon M. Baker
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
A major challenge in tissue engineering is the development of materials that can support angiogenesis, wherein endothelial cells from existing vasculature invade the surrounding matrix to form new vascular structures. To identify material properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::535c475872214404de20684b4096cc1e
https://pubmed.ncbi.nlm.nih.gov/28851858
https://pubmed.ncbi.nlm.nih.gov/28851858
Autor:
Brandon L. Blakely, David R. Liu, Colin K. Choi, Van K Duesterberg, Christoph E. Dumelin, Lynn M. McGregor, Christopher S. Chen, Peter C. Anthony, Britta Trappmann, Steven M. Block, Brendon M. Baker
Publikováno v:
Nature methods
We developed molecular tension probes (TPs) that report traction forces of adherent cells with high spatial resolution, can in principle be linked to virtually any surface, and obviate monitoring deformations of elastic substrates. TPs consist of DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b17e7bce27a825ad04fcb8b316bf0a8
http://europepmc.org/articles/PMC4247985
http://europepmc.org/articles/PMC4247985
Autor:
Daniel M. Cohen, Duc-Huy T. Nguyen, Christopher S. Chen, Peter A. Galie, Colin K. Choi, Paul A. Janmey
Publikováno v:
Proceedings of the National Academy of Sciences. 111:7968-7973
The density and architecture of capillary beds that form within a tissue depend on many factors, including local metabolic demand and blood flow. Here, using microfluidic control of local fluid mechanics, we show the existence of a previously unappre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3cc0a9528b4330ed16560ea0bf374dd
https://doi.org/10.1073/pnas.1310842111
https://doi.org/10.1073/pnas.1310842111
Autor:
Susie S. Cha, Sarah C. Stapleton, Michael T. Yang, Christopher S. Chen, Peter A. Galie, Colin K. Choi, Duc-Huy T. Nguyen
Publikováno v:
Proceedings of the National Academy of Sciences. 110:6712-6717
Angiogenesis is a complex morphogenetic process whereby endothelial cells from existing vessels invade as multicellular sprouts to form new vessels. Here, we have engineered a unique organotypic model of angiogenic sprouting and neovessel formation t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508c0c27d758f727b47495b449ce831a
https://doi.org/10.1073/pnas.1221526110
https://doi.org/10.1073/pnas.1221526110
Autor:
Wesley R. Legant, Jordan S. Miller, Christopher S. Chen, Lin Shao, Colin K. Choi, Liang Gao, Eric Betzig
Publikováno v:
Proceedings of the National Academy of Sciences. 110:881-886
Recent methods have revealed that cells on planar substrates exert both shear (in-plane) and normal (out-of-plane) tractions against the extracellular matrix (ECM). However, the location and origin of the normal tractions with respect to the adhesive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de0612652a30b1f8bcc91bbd8f891460
https://doi.org/10.1073/pnas.1207997110
https://doi.org/10.1073/pnas.1207997110