Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Colin J Ross"'
Autor:
Parvaz Madadi, Johanna Sistonen, Gregory Silverman, Rebecca Gladdy, Colin J Ross, Bruce C Carleton, Jose C Carvalho, Michael R Hayden, Gideon Koren
Publikováno v:
Pain Research and Management, Vol 18, Iss 3, Pp 133-136 (2013)
BACKGROUND: Systemic approaches are needed to understand how variations in the genes associated with opioid pharmacokinetics and response can be used to predict patient outcome. The application of pharmacogenetic analysis to two cases of life-threate
Externí odkaz:
https://doaj.org/article/0acaa1ee33b047b58f4731ee7fa292f5
Autor:
Amit P Bhavsar, Nat F Brown, Jan Stoepel, Marcel Wiermer, Dale D O Martin, Karolynn J Hsu, Koshi Imami, Colin J Ross, Michael R Hayden, Leonard J Foster, Xin Li, Phil Hieter, B Brett Finlay
Publikováno v:
PLoS Pathogens, Vol 9, Iss 7, p e1003518 (2013)
To further its pathogenesis, S. Typhimurium delivers effector proteins into host cells, including the novel E3 ubiquitin ligase (NEL) effector SspH2. Using model systems in a cross-kingdom approach we gained further insight into the molecular functio
Externí odkaz:
https://doaj.org/article/18d8300ef9bc4b3f815eb0cf4287600f
Autor:
Samina Ali, Aran Yukseloglu, Colin J. Ross, Rhonda J. Rosychuk, Amy L. Drendel, Robin Manaloor, David W. Johnson, Sylvie Le May, Bruce Carleton
Publikováno v:
PAIN Reports, Vol 8, Iss 6, p e1113 (2023)
Abstract. Introduction:. Individual genetic variation may influence clinical effects for pain medications. Effects of CYP2C9, CYP3A4, and CYP2D6 polymorphisms on clinical effectiveness and safety for ibuprofen and oxycodone were studied. Objective:.
Externí odkaz:
https://doaj.org/article/6b0e887903c54e3098aa14bc10f978ab
Autor:
Jennifer J. Lin, Catrina M. Loucks, Jessica N. Trueman, Britt I. Drögemöller, Galen E.B. Wright, Eric M. Yoshida, Jo-Ann Ford, Samuel S. Lee, Richard B. Kim, Bandar Al-Judaibi, Ute I. Schwarz, Alnoor Ramji, Edward Tam, Colin J. Ross, Bruce C. Carleton
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 143, Iss , Pp 112195- (2021)
Background: The current use of ribavirin in difficult-to-cure chronic hepatitis C patients (HCV) and patients with severe respiratory infections is constrained by the issue of ribavirin-induced hemolytic anemia that affects 30% of treated patients, r
Externí odkaz:
https://doaj.org/article/724bec238097474e9902ca6969efc72e
Autor:
Bhavi P. Modi, Haq Nawaz Khan, Robin van der Lee, Muhammad Wasim, Charlotte A. Haaxma, Phillip A. Richmond, Britt Drögemöller, Suleman Shah, Gajja Salomons, Frans M. van der Kloet, Fred M. Vaz, Saskia N. van der Crabben, Colin J. Ross, Wyeth W. Wasserman, Clara D.M. van Karnebeek, Fazli Rabbi Awan
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 27, Iss , Pp 100761- (2021)
Guanidinoacetate methyltransferase (GAMT) deficiency is a creatine deficiency disorder and an inborn error of metabolism presenting with progressive intellectual and neurological deterioration. As most cases are identified and treated in early childh
Externí odkaz:
https://doaj.org/article/0324e8d839f242b9b20895a59c5f16a5
Autor:
Hamid R. Razzaghian, Zohreh Sharafian, Ashish A. Sharma, Guilaine K. Boyce, Kelsey Lee, Rachel Da Silva, Paul C. Orban, Rafick-Pierre Sekaly, Colin J. Ross, Pascal M. Lavoie
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Newborns are frequently affected by mucocutaneous candidiasis. Th17 cells essentially limit mucosal invasion by commensal Candida spp. Here, we sought to understand the molecular basis for the developmental lack of Th17 cell responses in circulating
Externí odkaz:
https://doaj.org/article/28208e0f99b54cc9b66ac58a41238d23
Autor:
Kristen M. Gibson, Renate Kain, Raashid A. Luqmani, Colin J. Ross, David A. Cabral, Kelly L. Brown
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
BackgroundAnti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a small vessel vasculitis in adults and children that commonly affects the kidneys. Although the frequent antigenic, and presumed pathogenic, targets of ANCA in AAV
Externí odkaz:
https://doaj.org/article/70187071eeee4b02a91df5d0ed361dbb
Autor:
Erin E. Gill, Maren L. Smith, Kristen M. Gibson, Kimberly A. Morishita, Amy H. Y. Lee, Reza Falsafi, Jinko Graham, Dirk Foell, Susanne M. Benseler, Colin J. Ross, Raashid A. Luqmani, David A. Cabral, Robert E. W. Hancock, Kelly L. Brown, The PedVas Initiative Investigators
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Objectives: Chronic primary vasculitis describes a group of complex and rare diseases that are characterized by blood vessel inflammation. Classification of vasculitis subtypes is based predominantly on the size of the involved vessels and clinical p
Externí odkaz:
https://doaj.org/article/23de446f6ddd49a0b0f1f54ed32c14dc
Autor:
Kristen M, Gibson, Britt I, Drögemöller, Dirk, Foell, Susanne M, Benseler, Jinko, Graham, Robert E W, Hancock, Raashid A, Luqmani, David A, Cabral, Kelly L, Brown, Colin J, Ross, Heidi, Stapp
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.).
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare, life-threatening inflammation of blood vessels that can affect both adults and children. Compared to adult-onset disease, AAV is especially rare in children with an an
Autor:
Jessica L Vargas-Neri, Bruce Carleton, Colin J Ross, Mara Medeiros, Gilberto Castañeda-Hernández, Patricia Clark
Publikováno v:
Pharmacogenomics. 23(5)
Background: The aim of this study was to evaluate the association between well-defined genetic risk variants in SLC28A3, RARG and UGT1A6 and anthracycline-induced cardiotoxicity in Mexican pediatric patients. Methods: We tested a cohort of 79 childre