Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Colin Hanfrey"'
Publikováno v:
The Journal of Biological Chemistry
Polyamines are fundamental molecules of life, and their deep evolutionary history is reflected in extensive biosynthetic diversification. The polyamines putrescine, agmatine, and cadaverine are produced by pyridoxal 5′-phosphate-dependent L-ornithi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb0dff694aadb9359fc9f431c365189d
https://pubmed.ncbi.nlm.nih.gov/34560100
https://pubmed.ncbi.nlm.nih.gov/34560100
Autor:
Steven E. Ealick, Anthony J. Michael, Yang Zhang, Bin Li, Katherine A. Elliott, Colin Hanfrey, Sok Ho Kim
Publikováno v:
Molecular Microbiology. 97:791-807
The polyamine spermidine is absolutely required for growth and cell proliferation in eukaryotes, due to its role in post-translational modification of essential translation elongation factor eIF5A, mediated by deoxyhypusine synthase. We have found th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d799a8d6ef5f62ee80fcf440fa99ca8
https://doi.org/10.1111/mmi.13066
https://doi.org/10.1111/mmi.13066
Publikováno v:
Molecular Microbiology. 86:485-499
Summary Structural backbones of iron-scavenging siderophore molecules include polyamines 1,3-diaminopropane and 1,5-diaminopentane (cadaverine). For the cadaverine-based desferroxiamine E siderophore in Streptomyces coelicolor, the corresponding bios
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea11df7f80c7db15f2e4d9bbf92d6a5c
https://doi.org/10.1111/j.1365-2958.2012.08208.x
https://doi.org/10.1111/j.1365-2958.2012.08208.x
Autor:
Margaret A. Phillips, Duncan J. H. Gaskin, Colin Hanfrey, Jeongmi Lee, Patrick M. Woster, Stuart T. Hazeldine, Bruce M. Pearson, Anthony J. Michael
Publikováno v:
Journal of Biological Chemistry. 286:43301-43312
The availability of fully sequenced bacterial genomes has revealed that many species known to synthesize the polyamine spermidine lack the spermidine biosynthetic enzymes S-adenosylmethionine decarboxylase and spermidine synthase. We found that such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0defa076f0fc42cba803b3bc7c1b51be
https://doi.org/10.1074/jbc.m111.307835
https://doi.org/10.1074/jbc.m111.307835
Autor:
Anthony J. Michael, Robert T. Green, Colin Hanfrey, Anthony E. Pegg, Xiaojing Wang, Sreenivas Kanugula, Katherine A. Elliott, Diane E. McCloskey
Publikováno v:
Molecular Microbiology. 81:1109-1124
Summary We have identified gene fusions of polyamine biosynthetic enzymes S-adenosylmethionine decarboxylase (AdoMetDC, speD) and aminopropyltransferase (speE) orthologues in diverse bacterial phyla. Both domains are functionally active and we demons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02e33c3487db62a66e72a0bf3a8bbcb0
https://doi.org/10.1111/j.1365-2958.2011.07757.x
https://doi.org/10.1111/j.1365-2958.2011.07757.x
Publikováno v:
FEBS Letters. 582:503-509
Accumulation of unfolded proteins in the endoplasmic reticulum (ER) causes stress and induces the unfolded protein response (UPR). Genome-wide analysis of translational regulation in response to the UPR-inducing agent dithiothreitol in Saccharomyces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b9270c3fdc396192ba20e18b0c0eb4
https://doi.org/10.1016/j.febslet.2008.01.009
https://doi.org/10.1016/j.febslet.2008.01.009
Autor:
Anthony J. Michael, Colin Hanfrey, Katherine A. Elliott, Marina Franceschetti, Crista Illingworth, Melinda J. Mayer
Publikováno v:
Journal of Biological Chemistry. 280:39229-39237
A novel form of translational regulation is described for the key polyamine biosynthetic enzyme S-adenosylmethionine decarboxylase (AdoMetDC). Plant AdoMetDC mRNA 5' leaders contain two highly conserved overlapping upstream open reading frames (uORFs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a0364cf97ed2af61ad31e6c5ed45fa
https://doi.org/10.1074/jbc.m509340200
https://doi.org/10.1074/jbc.m509340200
Autor:
M. Collier, Barry Perry, Anthony J. Michael, Crista Illingworth, Katherine A. Elliott, Colin Hanfrey, Marina Franceschetti, Melinda J. Mayer, B. Thompson
Publikováno v:
Biochemical Society Transactions. 31:424-427
It is becoming apparent that control of protein synthesis by metabolites is more common than previously thought. Much of that control is exerted at the level of initiation of mRNA translation, orchestrated by upstream open reading frames (uORFs) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b55fd9d404e08ba6da96696191e6774c
https://doi.org/10.1042/bst0310424
https://doi.org/10.1042/bst0310424
Publikováno v:
The Plant Journal. 27:551-560
Unlike other eukaryotes, which can synthesize polyamines only from ornithine, plants possess an additional pathway from arginine. Occasionally non-enzymatic decarboxylation of ornithine could be detected in Arabidopsis extracts; however, we could not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a026f1808246a35065e01b4b23dcf430
https://doi.org/10.1046/j.1365-313x.2001.01100.x
https://doi.org/10.1046/j.1365-313x.2001.01100.x
Autor:
Marina FRANCESCHETTI, Colin HANFREY, Sonia SCARAMAGLI, Patrizia TORRIGIANI, Nello BAGNI, Daniel BURTIN, Anthony J. MICHAEL
Publikováno v:
Biochemical Journal. 353:403-409
S-Adenosyl-L-methionine decarboxylase (AdoMetDC; EC 4.1.1.50) is one of the key regulatory enzymes in the biosynthesis of polyamines. Isolation of genomic and cDNA sequences from rice and Arabidopsis had indicated that this enzyme is encoded by a sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1905fde73555194258c8967914d291e4
https://doi.org/10.1042/bj3530403
https://doi.org/10.1042/bj3530403