Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Colin G. Ferguson"'
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79065 (2013)
Autotaxin (ATX), an autocrine motility factor that is highly upregulated in metastatic cancer, is a lysophospholipase D enzyme that produces the lipid second messenger lysophosphatidic acid (LPA) from lysophosphatidylcholine (LPC). Dysregulation of t
Externí odkaz:
https://doaj.org/article/00777e01b3144866b5164acf3173668c
Publikováno v:
Analytical Chemistry. 84:8323-8329
Characterization of polymerized liposomes (PolyPIPosomes) was carried out using a combination of normal dc electrical field-flow fractionation and cyclical electrical field-flow fractionation (CyElFFF) as an analytical technique. The constant nature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e3d1528ec29512302e04ae4dd4c90f3
https://doi.org/10.1021/ac301424b
https://doi.org/10.1021/ac301424b
Autor:
Christian Chabert, Christian Arod, Karl Mechtler, Christian Rommel, Christian Pasquali, Montserrat Camps, Ioannis Xenarios, Dominique Bertschy-Meier, Randy Booth, Marie Laure Curchod, Francis Vilbois, Colin G. Ferguson, Glenn D. Prestwich
Publikováno v:
Molecular & Cellular Proteomics. 6:1829-1841
Prior work using lipid-based affinity matrices has been done to investigate distinct sets of lipid-binding proteins, and one series of experiments has proven successful in mammalian cells for the proteome-wide identification of lipid-binding proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9c7f7391eb200eb49d5ed766bf9e4c2
https://doi.org/10.1074/mcp.t600066-mcp200
https://doi.org/10.1074/mcp.t600066-mcp200
Autor:
Yasmina N Abdiche, Colin G. Ferguson, David G. Myszka, Cleve S. Bigman, Phinikoula S. Katsamba, Donnie A. Shepard, Robyn D. James, Glenn D. Prestwich
Publikováno v:
Bioconjugate Chemistry. 16:1475-1483
Stable phosphoinositide (PIP(n))-containing liposomes were prepared using polydiacetylene photochemistry. Tethered pentacosadiynyl inositol polyphosphate (InsP(n)) analogues of Ins(1,3,4)P(3), Ins(1,4,5)P(3), and Ins(1,3,4,5)P(4) were synthesized, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b154194898e4ff0c87f81566df70664
https://doi.org/10.1021/bc050197q
https://doi.org/10.1021/bc050197q
Autor:
Michael Overduin, Colin G. Ferguson, Tatiana G. Kutateladze, Glenn D. Prestwich, Daniel G. S. Capelluto, Andrei G. Kutateladze, Matthew L. Cheever
Publikováno v:
Journal of Biological Chemistry. 279:3050-3057
Targeting of a wide variety of proteins to membranes involves specific recognition of phospholipid head groups and insertion into lipid bilayers. For example, proteins that contain FYVE domains are recruited to endosomes through interaction with phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e4f3522510044829ce992ccee97e6a
https://doi.org/10.1074/jbc.m309007200
https://doi.org/10.1074/jbc.m309007200
Autor:
Gerhard Wagner, Philip Karuman, David R. Jones, Bernard Payrastre, David G. Myszka, Joan S. Brugge, Nullin Divecha, Jian Chen, Colin G. Ferguson, Or Gozani, Cheryl L. Baird, Glenn D. Prestwich, Bharat Mehrotra, Jennifer Villasenor, Dmitri N. Ivanov, Junying Yuan, Alexey Lugovskoy, Seth J. Field, James Cha, Hong Zhu, Stephen L. Lessnick, Vikram R. Rao, Lewis C. Cantley
Publikováno v:
Cell. 114(1):99-111
Phosphoinositides (PtdInsPs) play critical roles in cytoplasmic signal transduction pathways. However, their functions in the nucleus are unclear, as specific nuclear receptors for PtdInsPs have not been identified. Here, we show that ING2, a candida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc9dc36c8a589636309a87c69b2b0919
Publikováno v:
Journal of Biological Chemistry. 277:14068-14076
The myristoylated alanine-rich protein kinase C substrate (MARCKS) may function to sequester phosphoinositides within the plane of the bilayer. To characterize this interaction with phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)), a novel spin-la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f47217c413eb59dd724bc1bd798629b1
https://doi.org/10.1074/jbc.m109572200
https://doi.org/10.1074/jbc.m109572200
Publikováno v:
The Journal of Organic Chemistry. 65:1218-1221
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ec1e2c31545e717d7428ef72a3e1ca
https://doi.org/10.1021/jo9912909
https://doi.org/10.1021/jo9912909
Publikováno v:
Organic Letters. 1:829-832
[formula: see text] Aminocyclodextrins (ACDs), perfunctionalized at the 6-position with amino groups, bind phosphonoformate (PFA) diesters and accelerate acyl transfer reactions with high efficiency at neutral pH. Aminolysis and esterolysis are accel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29354d7f6c0cf71c7f28bfd28e4bb3f
https://doi.org/10.1021/ol9906211
https://doi.org/10.1021/ol9906211
Publikováno v:
Tetrahedron Letters. 38:2791-2794
The high reactivity of the phosphonoformate moiety requires development of a novel synthesis for esters of phosphonoformate, which is reported together with preliminary data on the antiviral activity of these esters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cdc4fb2d24054a110c27dbc7023cd83
https://doi.org/10.1016/s0040-4039(97)00491-7
https://doi.org/10.1016/s0040-4039(97)00491-7