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pro vyhledávání: '"Colin Fielding"'
Autor:
John S. Shaw, Martin Wild, Dearg S. Brown, Howard Tucker, Adrian John Highton, Alan Wellington Faull, John Oldfield, John G. Cumming, Colin Fielding, Stuart L. Wells
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:1655-1659
Modifications to a series of potent and selective substituted 1-(3,3-diphenylpropyl)-piperidine phenylacetamide CCR5 antagonists were explored with the aim of reducing affinity at the hERG cardiac ion channel. Replacement of one aromatic ring in the