Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Colin D. Ingram"'
Publikováno v:
Endocrinology
Hypothalamo-pituitary-adrenal (HPA) axis activity is subject to negative feedback control by glucocorticoids. Although the rapid component of this feedback is widely considered to contribute to regulation of dynamic HPA activity, few in vivo data exi
Autor:
Colin D. Ingram, Allan H. Young, Gareth O Minton, R McQuade, Sarah E. Gartside, Graeme Fairchild
Publikováno v:
Neuropsychopharmacology. 34:2265-2274
Patients with bipolar disorder have abnormalities in glucocorticoid secretion, dopaminergic neurotransmission, and prefrontal cortical function. We hypothesized that the flattening of the diurnal glucocorticoid rhythm, commonly seen in bipolar disord
Autor:
Christopher A. Lowry, Matthew W. Hale, Andrea Plant, Richard J. Windle, Nola Shanks, Susan A. Wood, Colin D. Ingram, Kenneth J. Renner, Stafford L. Lightman, Cliff H. Summers
Publikováno v:
Stress. 12:225-239
Corticotropin-releasing factor (CRF) is a potent neuromodulator of stress-related behaviour but the neural mechanisms underlying these effects are not clear. Studies were designed to test the hypothesis that CRF-induced behavioural arousal involves i
Publikováno v:
Neuropsychopharmacology. 34:399-409
The effects of combined treatment with a glucocorticoid receptor (GR) antagonist, Org 34850, and a selective serotonin reuptake inhibitor (SSRI), fluoxetine, were investigated on pre- and postsynaptic aspects of 5-HT neurotransmission. Rats were trea
Publikováno v:
Neuropeptides. 39:403-407
The lateral dorsal nucleus of the bed nuclei of the stria terminalis (BST-LD) expresses dense oxytocin binding while lower binding is detected in the medial anterior BST (BST-MA) and adjacent ventrolateral septum (VLS). However, in vitro examination
Autor:
M.G. Terenzi, Colin D. Ingram
Publikováno v:
Neuroscience. 134:345-354
Central oxytocin plays an important role in regulating emotionality. The amygdala expresses gonadal steroid-sensitive oxytocin binding sites in both the central and medial sub-nuclei, although the densities markedly differ between these nuclei. These
Autor:
Colin D. Ingram, Stafford L. Lightman, J. V. Seale, David S. Jessop, E. Bate, SA Wood, Helen C. Atkinson, Michael S. Harbuz
Publikováno v:
Journal of Neuroendocrinology. 16:516-524
Enhanced corticosterone release by female compared to male rats under basal and stress conditions is well documented. The demonstration that gonadectomy enhances stress-induced corticosterone secretion in male rats, but reduces such levels in female
Publikováno v:
Neuropharmacology. 45:925-934
Corticosteroid modulation of 5-HT(1A) receptor function may contribute to the aetiology of affective disorders. To examine this modulation, the effects of acute and chronic corticosterone administration on 5-HT(1A) autoreceptor function were investig
Publikováno v:
European Journal of Neuroscience. 17:2401-2408
Early life adversity is associated with an increased incidence of psychiatric illness in adulthood. Although the mechanisms underlying this association are unclear, one possible substrate is brain 5-hydroxytryptamine neurotransmission, which is repor
Publikováno v:
Hormones and Behavior. 43:254-262
The dorsomedial hypothalamus (DMH) plays an important role in relaying information to neural pathways mediating neuroendocrine, autonomic, and behavioral responses to stress. Evidence suggests that the DMH is a structurally and functionally diverse i