Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Colin D. Glen"'
Autor:
Colin D. Glen, Mariel Voutounou, Robert J. Hardwick, Safeer K. Mughal, Yuri E. Dubrova, Ruth C. Barber, Morag E. Shanks
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 664:6-12
It is well known that the developing embryo is especially sensitive to ionising radiation. However, to date little is known about the long-term effects of in utero exposure on mutation rates during adulthood. To evaluate the effects of in utero irrad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c282ae47cf2a045f154f711528d58305
https://doi.org/10.1016/j.mrfmmm.2009.01.011
https://doi.org/10.1016/j.mrfmmm.2009.01.011
Publikováno v:
Molecular nutritionfood research. 59(3)
cope Hepatocellular carcinoma is one of the most frequently occurring cancers in humans. Recent human and animal studies have provided strong evidence for the effects of dietary deficiency of methyl donors on the development of liver cancer. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba97406127e62685fb020056baa122b0
https://pubmed.ncbi.nlm.nih.gov/25488634
https://pubmed.ncbi.nlm.nih.gov/25488634
Autor:
Colin D. Glen, Paul M. Vanhoutte, Gillian Edwards, Michel Félétou, M J Gardener, G R Richards, Arthur H. Weston
Publikováno v:
British Journal of Pharmacology. 133:1145-1153
In porcine coronary arteries, smooth muscle hyperpolarizations produced by the nitric oxide donor, NOR-1, and the prostacyclin analogue, iloprost, were compared with those induced by substance P and bradykinin and attributed to the endothelium-derive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17928f4f21cdba7d2a016ed9997b9017
https://doi.org/10.1038/sj.bjp.0704157
https://doi.org/10.1038/sj.bjp.0704157
Publikováno v:
Mutation research. 734(1-2)
The results of recent human and animal studies have provided strong evidence for the epigenetic effects of a dietary deficiency of methyl donors such as folate, choline and methionine on cancer risk and some other common diseases. However, the mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb5396911039c4c55d9648f8cc2d7aa2
https://pubmed.ncbi.nlm.nih.gov/22569175
https://pubmed.ncbi.nlm.nih.gov/22569175
Autor:
Yuri E. Dubrova, Colin D. Glen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(8)
The genetic effects of human exposure to anticancer drugs remain poorly understood. To establish whether exposure to anticancer drugs can result not only in mutation induction in the germ line of treated animals, but also in altered mutation rates in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c18b7d66102a4202133c330cb5d8102
https://pubmed.ncbi.nlm.nih.gov/22308437
https://pubmed.ncbi.nlm.nih.gov/22308437
Publikováno v:
Cancer research. 68(10)
Understanding and estimating the genetic hazards of exposure to chemical mutagens and anticancer drugs in humans requires the development of efficient systems for monitoring germ line mutation. The suitability of a single-molecule PCR–based approac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd3302cb8167f0d93b436a3765a39851
https://pubmed.ncbi.nlm.nih.gov/18483245
https://pubmed.ncbi.nlm.nih.gov/18483245
Autor:
Colin D. Glen, Peter T. Hickenbotham, Ruth C. Barber, Hiu-Pak Wong, Karen Monger, Yuri E. Dubrova
Publikováno v:
Environmental and molecular mutagenesis. 49(4)
Recent data shows that the effects of ionizing radiation are not restricted to the directly exposed parental germ cells, but can also manifest in their nonexposed offspring, resulting in elevated mutation rates and cancer predisposition. The mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a248735fde75a0a1b315d3f3e55951
https://pubmed.ncbi.nlm.nih.gov/18366099
https://pubmed.ncbi.nlm.nih.gov/18366099
Publikováno v:
Toxicology. 278:377-378
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79d6df959e42fea2cbb657d7bc605f2f
https://doi.org/10.1016/j.tox.2010.08.144
https://doi.org/10.1016/j.tox.2010.08.144