Zobrazeno 1 - 10
of 544
pro vyhledávání: '"Colin Cooper"'
Autor:
Kostas A. Papageorgiou, Tayler E. Truhan, Colin Cooper, Radoslaw Rogoza, Julie Aitken Schermer
Publikováno v:
Acta Psychologica, Vol 237, Iss , Pp 103954- (2023)
Externí odkaz:
https://doaj.org/article/834dcb4458ca45a68106896bf199941b
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background The APOBEC3 (apolipoprotein B mRNA editing enzyme catalytic polypeptide 3) family of cytidine deaminases is responsible for two mutational signatures (SBS2 and SBS13) found in cancer genomes. APOBEC3 enzymes are activated in respo
Externí odkaz:
https://doaj.org/article/726228cf9f9642149bcbd187a12eda3a
Autor:
Fang Zhao, Ekaterina Olkhov-Mitsel, Shivani Kamdar, Renu Jeyapala, Julia Garcia, Rachel Hurst, Marcelino Yazbek Hanna, Robert Mills, Alexandra V. Tuzova, Eve O’Reilly, Sarah Kelly, Colin Cooper, The Movember Urine Biomarker Consortium, Daniel Brewer, Antoinette S. Perry, Jeremy Clark, Neil Fleshner, Bharati Bapat
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-12 (2018)
Abstract Background Prevention of unnecessary biopsies and overtreatment of indolent disease remains a challenge in the management of prostate cancer. Novel non-invasive tests that can identify clinically significant (intermediate-risk and high-risk)
Externí odkaz:
https://doaj.org/article/0ba5aac33c664dcd9ecbe8bd9de7e992
Autor:
Qi Wang, Heba Alshaker, Torsten Böhler, Shyam Srivats, Yimin Chao, Colin Cooper, Dmitri Pchejetski
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Many prostate cancers relapse after initial chemotherapy treatment. Combining molecular and chemotherapy together with encapsulation of drugs in nanocarriers provides effective drug delivery and toxicity reduction. We developed core shell li
Externí odkaz:
https://doaj.org/article/beda79c1f26c4da98ebe53b6842a492f
Autor:
Gkikas Magiorkinis, Philippa C. Matthews, Susan E. Wallace, Katie Jeffery, Kevin Dunbar, Richard Tedder, Jean L. Mbisa, Bernadette Hannigan, Effy Vayena, Peter Simmonds, Daniel S. Brewer, Abraham Gihawi, Ghanasyam Rallapalli, Lea Lahnstein, Tom Fowler, Christine Patch, Fiona Maleady-Crowe, Anneke Lucassen, Colin Cooper
Publikováno v:
Wellcome Open Research, Vol 4 (2019)
The identification of microbiological infection is usually a diagnostic investigation, a complex process that is firstly initiated by clinical suspicion. With the emergence of high-throughput sequencing (HTS) technologies, metagenomic analysis has un
Externí odkaz:
https://doaj.org/article/a6b174a5b6cb43b4a573153910c95f9c
Autor:
Jeremy Clark, Andreas Doll, Jaume Reventós, Colin Cooper, Juan Morote, Inés de Torres, Marta Llauradó, Jacques Planas, Eva Colás, Melania Montes, Tamara Sequeiros, Marta Garcia, Mireia Olivan, Marina Rigau
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 6, Pp 12620-12649 (2013)
In order to successfully cure patients with prostate cancer (PCa), it is important to detect the disease at an early stage. The existing clinical biomarkers for PCa are not ideal, since they cannot specifically differentiate between those patients wh
Externí odkaz:
https://doaj.org/article/553ffcd72d214caa9ed0b77620dca50c
Autor:
Colin Cooper
Publikováno v:
The Lancet Global Health, Vol 3, Iss 9, p e519 (2015)
Externí odkaz:
https://doaj.org/article/2c5c3eac86f64b39bbf534cbde0d4a18
Autor:
Young Seok Ju, Ludmil B Alexandrov, Moritz Gerstung, Inigo Martincorena, Serena Nik-Zainal, Manasa Ramakrishna, Helen R Davies, Elli Papaemmanuil, Gunes Gundem, Adam Shlien, Niccolo Bolli, Sam Behjati, Patrick S Tarpey, Jyoti Nangalia, Charles E Massie, Adam P Butler, Jon W Teague, George S Vassiliou, Anthony R Green, Ming-Qing Du, Ashwin Unnikrishnan, John E Pimanda, Bin Tean Teh, Nikhil Munshi, Mel Greaves, Paresh Vyas, Adel K El-Naggar, Tom Santarius, V Peter Collins, Richard Grundy, Jack A Taylor, D Neil Hayes, David Malkin, ICGC Breast Cancer Group, ICGC Chronic Myeloid Disorders Group, ICGC Prostate Cancer Group, Christopher S Foster, Anne Y Warren, Hayley C Whitaker, Daniel Brewer, Rosalind Eeles, Colin Cooper, David Neal, Tapio Visakorpi, William B Isaacs, G Steven Bova, Adrienne M Flanagan, P Andrew Futreal, Andy G Lynch, Patrick F Chinnery, Ultan McDermott, Michael R Stratton, Peter J Campbell
Publikováno v:
eLife, Vol 3 (2014)
Recent sequencing studies have extensively explored the somatic alterations present in the nuclear genomes of cancers. Although mitochondria control energy metabolism and apoptosis, the origins and impact of cancer-associated mutations in mtDNA are u
Externí odkaz:
https://doaj.org/article/a97bb2e0fa0f4eb19b17cd3f405b0385
Autor:
Damian Smedley, Asuman Demiroglu, Munah Abdul-Rauf, Carol Heatht, Colin Cooper, Janet Shipley, Nicholas C.P. Cross
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 1, Iss 4, Pp 349-355 (1999)
The ZNF198-FGFR1 fusion gene arises as a result of the t(8;13)(p11;g12) in the 8p11 myeloproliferative syndrome. To determine the transforming properties of this chimeric protein we transfected ZNF198-FGFR1 into the interleukin (IL)-3 dependent cell
Externí odkaz:
https://doaj.org/article/8b2aa741b0584f9aa3b351e45cd8875e
Autor:
Helen Patterson, Diana Barnes, Sandra Gill, James Spicer, Cyril Fisher, Merion Thomas, Robert Grimer, Chris Fletcher, Barry Gusterson, Colin Cooper
Publikováno v:
Sarcoma, Vol 1, Iss 1, Pp 17-22 (1997)
Purpose. Amplification of genetic sequences on chromosome 12q13 is frequently found in soft tissue tumours. However, for the MDM2 gene, over-expression of the MDM2 protein has not always been shown to accompany gene amplification, raising the possibi
Externí odkaz:
https://doaj.org/article/2e9bce4097ac44cf9a6dd5cb45e30931