Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Colin C. Duke"'
Autor:
Daniela Traini, Warwick J. Britton, John Gar Yan Chan, Hak-Kim Chan, Colin C. Duke, Angel Pang, Andrew J. McLachlan, Paul M. Young, Joseph C. Y. Chan, Vidya Perera, Anneliese S. Tyne
Publikováno v:
International Journal of Antimicrobial Agents. 45:319-323
A novel inhalable rifapentine dry powder formulation could improve pulmonary rifapentine concentrations resulting in a significantly shorter time to treat tuberculosis infection. The pharmacokinetics of rifapentine (20mg/kg) in healthy mice was compa
Autor:
Paul M. Young, Daniela Traini, John Gar Yan Chan, Warwick J. Britton, Joseph C. Y. Chan, Anneliese S. Tyne, Hak-Kim Chan, Colin C. Duke, Hui Xin Ong
Publikováno v:
Journal of Pharmaceutical Sciences. 103:1411-1421
Recent murine studies found that rifapentine, dosed daily, at least halved tuberculosis treatment times compared with standard rifampicin and isoniazid-containing regimens. However, in humans, an inhalable form of rifapentine may be necessary to cons
Publikováno v:
European Journal of Medicinal Chemistry. 63:415-422
Synthesis of the naturally occurred C- and O-prenylated tetrahydroxystilbenes and O-prenylated cinnamates was carried out by decarbonylative Heck reaction and selenium dioxide catalysed oxidation, respectively. In the decarbonylative Heck synthetic r
Publikováno v:
Phytochemistry. 81:126-132
Honey bees, Apis mellifera var ligustica, on Kangaroo Island, Australia, were found to collect propolis from the sticky exudate on the stem shoots and seed pods of an Australian endemic plant, Acacia paradoxa. Extracts of the plant stem shoots and se
Publikováno v:
Phytochemistry. 77:251-259
A prenylated cinnamic acid derivative as well as six prenylated tetrahydroxystilbenes were isolated from the ethyl acetate extract of propolis that originated from Kangaroo Island, Australia. Furthermore, six known stilbenes and two known flavanones
Publikováno v:
Green and Sustainable Chemistry. :123-127
An efficient method of isolating an anti-cancer sesquiterpene lactone, eremophila-1(10)-11(13)-dien-12,8?- olide, was developed from fresh Calomeria amaranthoides plant material on the basis of its non-polar vola-tile property. Steam distillation of
Publikováno v:
Chemistry and Physics of Lipids. 158:39-45
Allylic hydroxylated derivatives of the C18 unsaturated fatty acids were prepared from linoleic acid (LA) and conjugated linoleic acids (CLAs). The reaction of LA methyl ester with selenium dioxide (SeO(2)) gave mono-hydroxylated derivatives, 13-hydr
Publikováno v:
Chemistry and Physics of Lipids. 152:122-130
Methyl esters of gamma-linolenic acid, alpha-linolenic acid and stearidonic acid were epoxidised using m-chloroperbenzoic acid to achieve nine cis-monoepoxy-C18 fatty acid methyl esters (FAMEs), including novel methyl cis-monoepoxy derivatives of ste
Publikováno v:
Phytochemistry. 67:2550-2560
Literature indicates that herb-drug interaction of St. John's wort is largely due to increased metabolism of the co-administered drugs that are the substrates of cytochrome P450 (CYP) 3A4 enzyme, alteration of the activity and/or expression of the en
Publikováno v:
European Journal of Organic Chemistry. 2006:2970-2976
A new versatile synthetic route is described for the preparation of capsaicin-like molecules which contain an α-hydroxy ketone functional group mimicking the amide functional group in the capsaicin structure. The key reaction in this synthesis was t