Výsledky vyhledávání - "Colin Butter"

Akademický článek

Functional Alleles of Chicken BG Genes, Members of the Butyrophilin Gene Family, in Peripheral T Cells

Autor: Lei Chen, Michaela Fakiola, Karen Staines, Colin Butter, Jim Kaufman

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

γδ T cells recognize a wide variety of ligands in mammals, among them members of the butyrophilin (BTN) family. Nothing is known about γδ T cell ligands in chickens, despite there being many such cells in blood and lymphoid tissues, as well as in

Externí odkaz: https://doaj.org/article/dae69b751f5c4c7fac172c9044d6162e

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Akademický článek

A Versatile Panel of Reference Gene Assays for the Measurement of Chicken mRNA by Quantitative PCR.

Autor: Karen Staines, Ambalika Batra, William Mwangi, Helena J Maier, Steven Van Borm, John R Young, Mark Fife, Colin Butter

Publikováno v: PLoS ONE, Vol 11, Iss 8, p e0160173 (2016)

Quantitative real-time PCR assays are widely used for the quantification of mRNA within avian experimental samples. Multiple stably-expressed reference genes, selected for the lowest variation in representative samples, can be used to control random

Externí odkaz: https://doaj.org/article/c8461a3f2702493b9dbeea87f6d08f06

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Akademický článek

Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding

Publikováno v: eLife, Vol 4 (2015)

Highly polymorphic major histocompatibility complex (MHC) molecules are at the heart of adaptive immune responses, playing crucial roles in many kinds of disease and in vaccination. We report that breadth of peptide presentation and level of cell sur

Externí odkaz: https://doaj.org/article/401c28ae24f148d385a2c6b49fd379e2

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Akademický článek

Sequence of a complete chicken BG haplotype shows dynamic expansion and contraction of two gene lineages with particular expression patterns.

Publikováno v: PLoS Genetics, Vol 10, Iss 6, p e1004417 (2014)

Many genes important in immunity are found as multigene families. The butyrophilin genes are members of the B7 family, playing diverse roles in co-regulation and perhaps in antigen presentation. In humans, a fixed number of butyrophilin genes are fou

Externí odkaz: https://doaj.org/article/3bfc5bb7c6274a4188c491bf17d47bc0

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Akademický článek

Evolution of an expanded mannose receptor gene family.

Autor: Karen Staines, Lawrence G Hunt, John R Young, Colin Butter

Publikováno v: PLoS ONE, Vol 9, Iss 11, p e110330 (2014)

Sequences of peptides from a protein specifically immunoprecipitated by an antibody, KUL01, that recognises chicken macrophages, identified a homologue of the mammalian mannose receptor, MRC1, which we called MRC1L-B. Inspection of the genomic enviro

Externí odkaz: https://doaj.org/article/db74b82d3e604f10b1e646c7331e1a18

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Akademický článek

Expression of chicken DEC205 reflects the unique structure and function of the avian immune system.

Autor: Karen Staines, John R Young, Colin Butter

Publikováno v: PLoS ONE, Vol 8, Iss 1, p e51799 (2013)

The generation of appropriate adaptive immune responses relies critically on dendritic cells, about which relatively little is known in chickens, a vital livestock species, in comparison with man and mouse. We cloned and sequenced chicken DEC205 cDNA

Externí odkaz: https://doaj.org/article/a72cfff46bd144879b34308a8b4f40ce

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