Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Colin A, Hammond"'
Autor:
Juan Carlos Rivera-Mulia, Takayo Sasaki, Claudia Trevilla-Garcia, Naoto Nakamichi, David J. H.F. Knapp, Colin A. Hammond, Bill H. Chang, Jeffrey W. Tyner, Meenakshi Devidas, Jared Zimmerman, Kyle N. Klein, Vivek Somasundaram, Brian J. Druker, Tanja A. Gruber, Amnon Koren, Connie J. Eaves, David M. Gilbert
Publikováno v:
Blood Advances, Vol 3, Iss 21, Pp 3201-3213 (2019)
Abstract: Human B-cell precursor acute lymphoid leukemias (BCP-ALLs) comprise a group of genetically and clinically distinct disease entities with features of differentiation arrest at known stages of normal B-lineage differentiation. We previously s
Externí odkaz:
https://doaj.org/article/813e5445336443a09e50cbf90d7c35a2
Autor:
Tony Hui, Qi Cao, Joanna Wegrzyn-Woltosz, Kieran O'Neill, Colin A. Hammond, David J.H.F. Knapp, Emma Laks, Michelle Moksa, Samuel Aparicio, Connie J. Eaves, Aly Karsan, Martin Hirst
Publikováno v:
Stem Cell Reports, Vol 11, Iss 2, Pp 578-592 (2018)
Summary: Increasing evidence of functional and transcriptional heterogeneity in phenotypically similar cells examined individually has prompted interest in obtaining parallel methylome data. We describe the development and application of such a proto
Externí odkaz:
https://doaj.org/article/2e0fa26ae7804df3820af3c233fd2998
Autor:
Poul H. Sorensen, Dimiter S. Dimitrov, Olivier Delattre, Gregg B. Morin, Li-Yan Xu, Rimas J. Orentas, Ramon I. Klein Geltink, Seth J. Parker, Mads Daugaard, Anne Steino, Amy Li, Sonia H.Y. Kung, Jonathan K.M. Lim, Sofya Langman, Anne-Chloe Dhez, Colin A. Hammond, Renata Scopim-Ribeiro, Taras Shyp, Shane Colborne, Htoo Zarni Oo, Michael M. Lizardo, Maj Sofie Ørum-Madsen, Xiaojun Li, Gian Luca Negri, Alberto Delaidelli, Anna Prudova, Hongwei Cheng, Amal M. El-Naggar, Didier Surdez, Jian-Zhong He, Wei Li, Christopher S. Hughes, Hai-Feng Zhang
Supplementary Data from Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e6166f1c594b2194af8072175d86fe
https://doi.org/10.1158/2159-8290.22540877
https://doi.org/10.1158/2159-8290.22540877
Autor:
Poul H. Sorensen, Dimiter S. Dimitrov, Olivier Delattre, Gregg B. Morin, Li-Yan Xu, Rimas J. Orentas, Ramon I. Klein Geltink, Seth J. Parker, Mads Daugaard, Anne Steino, Amy Li, Sonia H.Y. Kung, Jonathan K.M. Lim, Sofya Langman, Anne-Chloe Dhez, Colin A. Hammond, Renata Scopim-Ribeiro, Taras Shyp, Shane Colborne, Htoo Zarni Oo, Michael M. Lizardo, Maj Sofie Ørum-Madsen, Xiaojun Li, Gian Luca Negri, Alberto Delaidelli, Anna Prudova, Hongwei Cheng, Amal M. El-Naggar, Didier Surdez, Jian-Zhong He, Wei Li, Christopher S. Hughes, Hai-Feng Zhang
Cancer cells must overcome anoikis (detachment-induced death) to successfully metastasize. Using proteomic screens, we found that distinct oncoproteins upregulate IL1 receptor accessory protein (IL1RAP) to suppress anoikis. IL1RAP is directly induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8bdb1c5f12ead9674106bc25ce091c7
https://doi.org/10.1158/2159-8290.c.6549488.v1
https://doi.org/10.1158/2159-8290.c.6549488.v1
Autor:
Colin A. Hammond, Connie J. Eaves
Publikováno v:
Experimental Hematology. 109:18-26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b73925229a9e0bef61f3b9dbe165b64
https://doi.org/10.1016/j.exphem.2022.03.004
https://doi.org/10.1016/j.exphem.2022.03.004
Publikováno v:
Blood.
Human hematopoietic stem cells (HSCs), like their counterparts in mice, comprise a functionally and molecularly heterogeneous population of cells throughout life that, collectively, maintain required outputs of mature blood cellsunder homeostatic con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51546175f94a1963fb79a10969079196
https://doi.org/10.1182/blood.2022017174
https://doi.org/10.1182/blood.2022017174
Autor:
Massimo Carraro, Ivo A. Hendriks, Colin M. Hammond, Victor Solis, Moritz Völker-Albert, Jonas D. Elsborg, Melanie B. Weisser, Christos Spanos, Guillermo Montoya, Juri Rappsilber, Axel Imhof, Michael L. Nielsen, Anja Groth
Publikováno v:
Carraro, M, Hendriks, I A, Hammond, C M, Solis-Mezarino, V, Völker-Albert, M, Elsborg, J D, Weisser, M B, Spanos, C, Montoya, G, Rappsilber, J, Imhof, A, Nielsen, M L & Groth, A 2023, ' DAXX adds a de novo H3.3K9me3 deposition pathway to the histone chaperone network ', Molecular Cell, vol. 83, no. 7, pp. 1075-1092.e9 . https://doi.org/10.1016/j.molcel.2023.02.009
SUMMARYA multitude of histone chaperones are required to protect histones after their biosynthesis until DNA deposition. They cooperate through the formation of co-chaperone complexes, but the crosstalk between nucleosome assembly pathways remains en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec4ad9764888507b5e2b5ecb4ef9c06
https://doi.org/10.1016/j.molcel.2023.02.009
https://doi.org/10.1016/j.molcel.2023.02.009
Autor:
Garry P. Nolan, Sean C. Bendall, Carl L. Hansen, Connie J. Eaves, Fangwu Wang, Michael VanInsberghe, Colin A. Hammond, Paul H. Miller, Davide Pellacani, Nima Aghaeepour, Philip A. Beer, David J.H.F. Knapp
Publikováno v:
Blood. 133:927-939
Recent advances in single-cell molecular analytical methods and clonal growth assays are enabling more refined models of human hematopoietic lineage restriction processes to be conceptualized. Here, we report the results of integrating single-cell pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15fcce0c1303eea8c8f18302eaa1affd
https://doi.org/10.1182/blood-2018-10-878025
https://doi.org/10.1182/blood-2018-10-878025
Autor:
Amy Li, Anna Prudova, Amal El-Naggar, Hongwei Cheng, Dimiter S. Dimitrov, Jian-Zhong He, Colin A. Hammond, Seth J. Parker, Rimas J. Orentas, Taras Shyp, Renata Scopim-Ribeiro, Xiaojun Li, Olivier Delattre, Christopher S. Hughes, Alberto Delaidelli, Mads Daugaard, Sonia H.Y. Kung, Htoo Zarni Oo, Jonathan K M Lim, Wei Li, Poul H. Sorensen, Hai-Feng Zhang, Anne-Chloe Dhez, Michael M. Lizardo, Shane Colborne, Anne Steino, Didier Surdez, Sofya Langman, Ramon I. Klein Geltink, Gregg B. Morin, Maj Sofie Ørum-Madsen, Li-Yan Xu, Gian Luca Negri
Publikováno v:
Cancer discovery. 11(11)
Cancer cells must overcome anoikis (detachment-induced death) to successfully metastasize. Using proteomic screens, we found that distinct oncoproteins upregulate IL1 receptor accessory protein (IL1RAP) to suppress anoikis. IL1RAP is directly induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f58372c7bc044957b61cb01088bac3
https://pubmed.ncbi.nlm.nih.gov/34725089
https://pubmed.ncbi.nlm.nih.gov/34725089
Autor:
Martin Hirst, Connie J. Eaves, Jeremy Yeyan Shu, Davide Pellacani, Andrew P. Weng, Annaick Carles, Sylvain Lefort, Brian T. Wilhelm, Naoto Nakamichi, Philip A. Beer, Elizabeth Bulaeva, Colin A. Hammond, Alireza Lorzadeh, Michelle Moksa, Mikhail Bilenky
Publikováno v:
Blood. 136(24)
Hematopoietic clones with leukemogenic mutations arise in healthy people as they age, but progression to acute myeloid leukemia (AML) is rare. Recent evidence suggests that the microenvironment may play an important role in modulating human AML popul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d11fccf54bf6872e792c3f4f38b67f94
https://pubmed.ncbi.nlm.nih.gov/33301029
https://pubmed.ncbi.nlm.nih.gov/33301029