Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Colin Zhang"'
Autor:
Colin Zhang, Kelum Chamara Manoj Lakmal Elvitigala, Wildan Mubarok, Yasunori Okano, Shinji Sakai
Publikováno v:
Virtual and Physical Prototyping, Vol 19, Iss 1 (2024)
Extrusion-based 3D bioprinting has revolutionised tissue engineering, enabling complex biostructure manufacturing. However, extrusion imposes substantial shear stress on cells, compromising cell viability. Predicting and optimising cell viability rem
Externí odkaz:
https://doaj.org/article/0acb8dc28dd74d6599c50b56fb41752c
Autor:
Colin, Zhang, Meizhong, Xu, Chunhong, He, Jincong, Zhuo, David M, Burns, Ding-Quan, Qian, Qiyan, Lin, Yun-Long, Li, Lihua, Chen, Eric, Shi, Costas, Agrios, Linkai, Weng, Vaqar, Sharief, Ravi, Jalluri, Yanlong, Li, Peggy, Scherle, Sharon, Diamond, Deborah, Hunter, Maryanne, Covington, Cindy, Marando, Richard, Wynn, Kamna, Katiyar, Nancy, Contel, Kris, Vaddi, Swamy, Yeleswaram, Gregory, Hollis, Reid, Huber, Steve, Friedman, Brian, Metcalf, Wenqing, Yao
Publikováno v:
SSRN Electronic Journal.
11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) has been identified as the primary enzyme responsible for the activation of hepatic cortisone to cortisol in specific peripheral tissues resulting in the concomitant antagonism of insulin action within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3692552a04b6f880ed62ecd30b202590
https://doi.org/10.2139/ssrn.4056120
https://doi.org/10.2139/ssrn.4056120
Autor:
Santiago Jimenez-Serrano, Jose M. Benlloch, Jingyi Cheng, Constant Morera, Guangyu Liu, Javier Cuallado, Victor Ilisie, Laura Moliner, Colin Zhang, María José Rodríguez-Álvarez, Jorge Alamo
Publikováno v:
15th International Workshop on Breast Imaging (IWBI2020).
In this work we present the BiPlanar Breast PET (BBPET) system. It is composed of two movable paddles than can be placed in several configurations in order to allow the imaging of the breast and the pectoral wall. Each paddle is formed by several det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bda6270b9d7deaeb16c7bb6234b7232a
https://doi.org/10.1117/12.2564346
https://doi.org/10.1117/12.2564346
Autor:
Costas Agrios, Brian Metcalf, Lingkai Weng, Ding-Quan Qian, David M. Burns, Yun-Long Li, Jincong Zhuo, Colin Zhang, Meizhong Xu, Qiyan Lin, Chunhong He, Eric Shi, Wenqing Yao
Publikováno v:
Synlett. 2007:0460-0464
An efficient asymmetric synthesis of conformationally constrained (2S,3S)-piperidinedicarboxylic acid derivatives starting from L-aspartic acid β-tert-butyl ester and 3-chloro-2-(chloromethyl)-1-propene is described. The key steps involve N-alkylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ecff296c2c3f79070f2e572b0dd7cac
https://doi.org/10.1055/s-2007-968029
https://doi.org/10.1055/s-2007-968029
Autor:
Lingkai Weng, Qiyan Lin, Ravi Kumar Jalluri, Eric Shi, Maryanne Covington, Ding-Quan Qian, Peggy Scherle, Timothy Burn, Jordan S. Fridman, Kamna Katiyar, Costas Agrios, Max Pan, Kris Vaddi, Changnian Liu, Zelda Wasserman, Nancy Taylor, Eian Caulder, Wenqing Yao, Robert C. Newton, Gregory Hollis, Steven Friedman, Yanlong Li, Bing-Bing Zhou, Yun-Long Li, Michael J. Bower, Chunhong He, Xiangdong Liu, Colin Zhang, Jincong Zhuo, Meizhong Xu, Swamy Yeleswaram, David M. Burns, Cindy A. Marando, Richard Wynn, Brian Metcalf
Publikováno v:
Journal of Medicinal Chemistry. 50:603-606
The design, synthesis, evaluation, and identification of a novel class of (6S,7S)-N-hydroxy-6-carboxamide-5-azaspiro[2.5]octane-7-carboxamides as the first potent and selective inhibitors of human epidermal growth factor receptor-2 (HER-2) sheddase i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baef3a8ed08b12286d84bda86fa256d1
https://doi.org/10.1021/jm061344o
https://doi.org/10.1021/jm061344o
Autor:
Yun-Long Li, Brian Metcalf, Richard Wynn, Mark Stow, Yanlong Li, Qiyan Lin, Kamna Katiyar, Eric Shi, Costas Agrios, Vaqar Sharief, Lingkai Weng, Reid Huber, Steven M. Friedman, Peggy A. Scherle, Timothy Burn, Xiangdong Liu, Meizhong Xu, Gregory F. Hollis, Colin Zhang, David M. Burns, Dawn Ellis, Robert Newton, Phillip Liu, Cindy Marando, Maryanne B. Covington, Chunhong He, M.C. Hillman, Gengjie Yang, Jincong Zhuo, Mark Rupar, Ding-Quan Qian, Wenqing Yao, Kenneth Abremski, Jodi D. Bradley
Publikováno v:
Cancer Biology & Therapy. 5:657-664
Overexpression and activating mutations of ErbB family members have been implicated in the development and progression of a variety of tumor types. Cleavage of the HER2 receptor by an as yet unidentified ectodomain sheddase has been shown to liberate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c435ae0c30ea356f73c04aba227fa78d
https://doi.org/10.4161/cbt.5.6.2708
https://doi.org/10.4161/cbt.5.6.2708
Autor:
Gregory Hollis, Reid Huber, Swamy Yeleswaram, Maryanne Covington, Peggy Scherle, Timothy Burn, Chunhong He, Colin Zhang, Kris Vaddi, Richard Wynn, Lynn Leffet, Holly Koblish, Darlise DiMatteo, Karen Gallagher, Phillip Liu, Kevin Bowman, Wenqing Yao, Michael Hansbury, Yue Zhang, Mark Rupar, Ronald M. Klabe, Liangxing Wu, Paul Collier
Publikováno v:
Cancer Research. 75:771-771
Aberrant signaling through Fibroblast Growth Factor Receptors (FGFR) has been reported in multiple types of human cancers. Genomic analyses of squamous cell lung, gastric and urothelial tumors have revealed recurrent genetic alterations in FGFR1, FGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e01ce12e7926838965bce34b6d7c5fa
https://doi.org/10.1158/1538-7445.am2015-771
https://doi.org/10.1158/1538-7445.am2015-771
Autor:
Yun-Long Li, Wenqing Yao, Eric Shi, Jordan S. Fridman, Maryanne Covington, Peggy Scherle, Ding-Quan Qian, Jincong Zhuo, Kamna Katiyar, Colin Zhang, Meizhong Xu, David M. Burns, Cindy A. Marando, Richard Wynn, Steve Friedman, Yanlong Li, Chunhong He, Brian Metcalf
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(13)
A serendipitous discovery that the metalloprotease binding profile of a novel class of 2-carboxamide-3-hydroxamic acid piperidines could be significantly attenuated by the modification of the unexplored P1 substituent enabled the design and synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed15c6394336e639e5722ae7c33a8f8
https://pubmed.ncbi.nlm.nih.gov/19457660
https://pubmed.ncbi.nlm.nih.gov/19457660
Autor:
Max Pan, Kris Vaddi, David M. Burns, Zelda Wasserman, Yanlong Li, Swamy Yeleswaram, Cindy A. Marando, Meizhong Xu, Eric Shi, Peggy Scherle, Ding-Quan Qian, Chunhong He, Wenqing Yao, Steve Friedman, Robert C. Newton, Jincong Zhuo, Jordan S. Fridman, Xiangdong Liu, Gengjie Yang, Colin Zhang, Maryanne Covington, Yun-Long Li, Gregory Hollis, Brian Metcalf
Publikováno v:
Bioorganicmedicinal chemistry letters. 18(1)
In an effort to obtain a MMP selective and potent inhibitor of HER-2 sheddase (ADAM-10), the P1' group of a novel class of (6S,7S)-7-[(hydroxyamino)carbonyl]-6-carboxamide-5-azaspiro[2.5]octane-5-carboxylates was attenuated and the structure-activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a30f6e3ce914b7b9f9127cef9b10709
https://pubmed.ncbi.nlm.nih.gov/18036818
https://pubmed.ncbi.nlm.nih.gov/18036818