Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Colette vom Berg"'
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
The last decade has seen the adverse outcome pathways (AOP) framework become one of the most powerful tools in chemical risk assessment, but the development of new AOPs remains a slow and manually intensive process. Here, we present a faster approach
Externí odkaz:
https://doaj.org/article/237608b48d0e45fc867688b44906cf22
Autor:
Anne E. Thessen, Skylar Marvel, J. C. Achenbach, Stephan Fischer, Melissa A. Haendel, Kimberly Hayward, Nils Klüver, Sarah Könemann, Jessica Legradi, Pamela Lein, Connor Leong, J. Erik Mylroie, Stephanie Padilla, Dante Perone, Antonio Planchart, Rafael Miñana Prieto, Arantza Muriana, Celia Quevedo, David Reif, Kristen Ryan, Evelyn Stinckens, Lisa Truong, Lucia Vergauwen, Colette Vom Berg, Mitch Wilbanks, Bianca Yaghoobi, Jon Hamm
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Toxicological evaluation of chemicals using early-life stage zebrafish (Danio rerio) involves the observation and recording of altered phenotypes. Substantial variability has been observed among researchers in phenotypes reported from similar studies
Externí odkaz:
https://doaj.org/article/aa31689544a84557af841ca42ae42ad4
Autor:
Roman A. Li, Marja Talikka, Sylvain Gubian, Colette vom Berg, Florian Martin, Manuel C. Peitsch, Julia Hoeng, Anze Zupanic
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Adverse outcomes that result from chemical toxicity are rarely caused by dysregulation of individual proteins; rather, they are often caused by system-level perturbations in networks of molecular events. To fully understand the mechanisms of toxicity
Externí odkaz:
https://doaj.org/article/2dfc80e36e00424f99ea24accbf45c1d
Publikováno v:
Environmental Science & Technology. 55:11835-11847
In agricultural areas, insecticides inevitably reach water bodies via leaching or run-off. While designed to be neurotoxic to insects, insecticides have adverse effects on a multitude of organisms due to the high conservation of the nervous system am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b79f9eaafde7811b49299b81a35f49
https://doi.org/10.1021/acs.est.1c01792
https://doi.org/10.1021/acs.est.1c01792
Publikováno v:
Environmental Toxicology and Chemistry. 40:989-1006
The occurrence of neuroactive chemicals in the aquatic environment is on the rise and poses a potential threat to aquatic biota of currently unpredictable outcome. In particular, subtle changes caused by these chemicals to an organism's sensation or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::269bd1505bea0227c29ebe83da9e5744
https://doi.org/10.1002/etc.4951
https://doi.org/10.1002/etc.4951
Publikováno v:
Environmental sciencetechnology. 56(12)
Owing to the importance of acetylcholine as a neurotransmitter, many insecticides target the cholinergic system. Across phyla, cholinergic signaling is essential for many neuro-developmental processes including axonal pathfinding and synaptogenesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36bef216cd932f5fc0a20a46129e82f0
https://pubmed.ncbi.nlm.nih.gov/35575681
https://pubmed.ncbi.nlm.nih.gov/35575681
Autor:
Vincenzo Belcastro, Anze Zupanic, Sumit Madan, Julia Hoeng, Marja Talikka, Justyna Szostak, Colette vom Berg, Roman Li, Jens Dörpinghaus, Florian Martin, Manuel C. Peitsch
Publikováno v:
Chemical Research in Toxicology. 33:2550-2564
Transcriptomic approaches can give insight into molecular mechanisms underlying chemical toxicity and are increasingly being used as part of toxicological assessments. To aid the interpretation of transcriptomic data, we have developed a systems toxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e946ee3633fd16d67186f68ca64ff90
https://doi.org/10.1021/acs.chemrestox.0c00095
https://doi.org/10.1021/acs.chemrestox.0c00095
Publikováno v:
Environmental sciencetechnology. 56(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5747760943077948b0d5536f07753de4
https://pubmed.ncbi.nlm.nih.gov/34974706
https://pubmed.ncbi.nlm.nih.gov/34974706
Publikováno v:
Chemosphere. 317:137874
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0c39c5eecac84528e931d9c46ce59af
https://doi.org/10.1016/j.chemosphere.2023.137874
https://doi.org/10.1016/j.chemosphere.2023.137874
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports, 9 (1)
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports, 9 (1)
The analysis of larval zebrafish locomotor behavior has emerged as a powerful indicator of perturbations in the nervous system and is used in many fields of research, including neuroscience, toxicology and drug discovery. The behavior of larval zebra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b868cdfecd9545d74cf7c2d9be7fefd
http://europepmc.org/articles/PMC6754443
http://europepmc.org/articles/PMC6754443