Complementary biobank of rodent tissue samples to study the effect of World Trade Center exposure on cancer development

Autor: Wil Lieberman-Cribbin, Stephanie Tuminello, Christina Gillezeau, Maaike van Gerwen, Rachel Brody, David J. Mulholland, Lori Horton, Maureen Sisco, Colette Prophete, Judith Zelikoff, Hyun-Wook Lee, Sung-Hyun Park, Lung-Chi Chen, Mitchell D. Cohen, Emanuela Taioli

Publikováno v: Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-8 (2019)

Abstract World Trade Center (WTC) responders were exposed to mixture of dust, smoke, chemicals and carcinogens. New York University (NYU) and Mount Sinai have recreated WTC exposure in rodents to observe the resulting systemic and local biological re

Externí odkaz: https://doaj.org/article/e242335de01247d4b50cabdb57c73a10

Comparison of WTC dust size on macrophage inflammatory cytokine release in vivo and in vitro.

Autor: Michael D Weiden, Bushra Naveed, Sophia Kwon, Leopoldo N Segal, Soo Jung Cho, Jun Tsukiji, Rohan Kulkarni, Ashley L Comfort, Kusali J Kasturiarachchi, Colette Prophete, Mitchell D Cohen, Lung-Chi Chen, William N Rom, David J Prezant, Anna Nolan

Publikováno v: PLoS ONE, Vol 7, Iss 7, p e40016 (2012)

The WTC collapse exposed over 300,000 people to high concentrations of WTC-PM; particulates up to ∼50 mm were recovered from rescue workers' lungs. Elevated MDC and GM-CSF independently predicted subsequent lung injury in WTC-PM-exposed workers. Ou

Externí odkaz: https://doaj.org/article/a40316e6b2204d9783a51268b16a3aec

Supplementary Data 3 from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade

Autor: William K. Oh, Emanuela Taioli, Jun Zhu, Matthew Galsky, Stuart A. Aaronson, Michael J. Donovan, Mayte Suarez-Farinas, Dana Hashim, Lung-Chi Chen, Judith Zelikoff, Hyun-Wook Lee, Sung-Hyun Park, Maureen Sisco, Lori Horton, Colette Prophete, Mitchell D. Cohen, Naomi Alpert, Haocheng Yu, Li Wang, Yixuan Gong

Differentially expressed genes in rat prostates exposed to WTC dusts

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1140e5a1566075c1e7e9f5cd26ae25eb
https://doi.org/10.1158/1541-7786.22513347

Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade

Autor: William Oh, Judith T. Zelikoff, Li Wang, Yixuan Gong, Jun Zhu, Mayte Suárez-Fariñas, Colette Prophete, Naomi Alpert, Michael J. Donovan, Hyun-Wook Lee, Lori Horton, Emanuela Taioli, Maureen Sisco, Dana Hashim, Matthew D. Galsky, Haocheng Yu, Mitchell D. Cohen, Lung Chi Chen, Stuart A. Aaronson, Sung-Hyun Park

Publikováno v: Molecular Cancer Research. 17:1605-1612

An excess incidence of prostate cancer has been identified among World Trade Center (WTC) responders. In this study, we hypothesized that WTC dust, which contained carcinogens and tumor-promoting agents, could facilitate prostate cancer development b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b34a557972d6e826b833c49fe0b347
https://doi.org/10.1158/1541-7786.mcr-19-0115

Longitudinal Impact of WTC Dust Inhalation on Rat Cardiac Tissue Transcriptomic Profiles

Autor: Sung-Hyun Park, Yuting Lu, Yongzhao Shao, Colette Prophete, Lori Horton, Maureen Sisco, Hyun-Wook Lee, Thomas Kluz, Hong Sun, Max Costa, Judith Zelikoff, Lung-Chi Chen, Matthew W. Gorr, Loren E. Wold, Mitchell D. Cohen

Publikováno v: International Journal of Environmental Research and Public Health, Vol 19, Iss 919, p 919 (2022)
International Journal of Environmental Research and Public Health; Volume 19; Issue 2; Pages: 919
International Journal of Environmental Research and Public Health

First responders (FR) exposed to the World Trade Center (WTC) Ground Zero air over the first week after the 9/11 disaster have an increased heart disease incidence compared to unexposed FR and the general population. To test if WTC dusts were causati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2214e4b9c8d5f51e0499ccc8a7186d11
https://doi.org/10.3390/ijerph19020919