Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Colette M Johnston"'
Autor:
Colette M Johnston, Frances L Lovell, Daniel A Leongamornlert, Barbara E Stranger, Emmanouil T Dermitzakis, Mark T Ross
Publikováno v:
PLoS Genetics, Vol 4, Iss 1, p e9 (2008)
X chromosome inactivation in female mammals results in dosage compensation of X-linked gene products between the sexes. In humans there is evidence that a substantial proportion of genes escape from silencing. We have carried out a large-scale analys
Externí odkaz:
https://doaj.org/article/04ba7b2a52744328a2f8e8e84e3c168d
Autor:
Sohaila Rastan, Sarah M. Duthie, Neil Brockdorff, Gian-Carlo Alghisi, Emma J. Formstone, Alistair E. T. Newall, Colette M. Johnston, Steven A. Sheardown, Tatyana B. Nesterova, Ruth M. Arkell
Publikováno v:
Genetical Research. 72:59-72
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2611a7168eec19d7ca0ba0897fab0ded
https://doi.org/10.1017/s0016672398543303
https://doi.org/10.1017/s0016672398543303
Autor:
Colette M. Johnston, Sohaila Rastan, Steven A. Sheardown, Neil Brockdorff, D. P. Norris, Alistair E. T. Newall
Publikováno v:
Genetical Research. 70:79-89
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aafc682c6100c726865c233b568cf77c
https://doi.org/10.1017/s0016672397212863
https://doi.org/10.1017/s0016672397212863
Autor:
Daniel Leongamornlert, Mark T. Ross, Frances L Lovell, Colette M Johnston, Barbara E. Stranger, Emmanouil T. Dermitzakis
Publikováno v:
PLoS Genetics, Vol 4, Iss 1, p e9 (2008)
PLOS Genetics, Vol. 4, No 1 (2008) P. e9
PLoS Genetics
PLOS Genetics, Vol. 4, No 1 (2008) P. e9
PLoS Genetics
X chromosome inactivation in female mammals results in dosage compensation of X-linked gene products between the sexes. In humans there is evidence that a substantial proportion of genes escape from silencing. We have carried out a large-scale analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc375c30f78921b0390f601f9a20a3c1
http://europepmc.org/articles/PMC2213701?pdf=render
http://europepmc.org/articles/PMC2213701?pdf=render
Autor:
Maria Alexiou, Ruth Appanah, Alistair E. T. Newall, Colette M. Johnston, Neil Brockdorff, Jonathan Godwin, Tatyana B. Nesterova
The X-inactive-specific transcript (Xist) locus is acis-acting switch that regulates X chromosome inactivation in mammals. Over recent years an important goal has been to understand howXistis regulated at the initiation of X inactivation. Here we rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e9e40af5b6d77eda2fa8b7b857e768
https://europepmc.org/articles/PMC196458/
https://europepmc.org/articles/PMC196458/
Autor:
Sergey Ya. Slobodyanyuk, Alexander I. Shevchenko, Nikolay N. Kolesnikov, Tatyana B. Nesterova, Marina E. Pavlova, Suren M. Zakian, Eugene A. Elisaphenko, Neil Brockdorff, Colette M. Johnston, Igor B. Rogozin
The Xist locus plays a central role in the regulation of X chromosome inactivation in mammals, although its exact mode of action remains to be elucidated. Evolutionary studies are important in identifying conserved genomic regions and defining their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07fda4310fe0f7f4d1908b722cd7d3ab
https://europepmc.org/articles/PMC311126/
https://europepmc.org/articles/PMC311126/
Autor:
Emma J. Formstone, Tatyana B. Nesterova, Colette M. Johnston, Maria Alexiou, Alistair E. T. Newall, Sarah M. Duthie, Marie-Laure Caparros, Neil Brockdorff
Publikováno v:
Human molecular genetics. 10(6)
In this report we demonstrate primary non-random X chromosome inactivation following targeted mutagenesis of a region immediately upstream of XIST promoter P(1). In heterozygous animals there is a preferential inactivation of the targeted X chromosom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f027af33ed97873df056ac3c52335fe8
https://pubmed.ncbi.nlm.nih.gov/11230177
https://pubmed.ncbi.nlm.nih.gov/11230177
Autor:
Neil Brockdorff, Steven A. Sheardown, Emma J. Formstone, Sarah M. Duthie, Colette M. Johnston, Tatyana B. Nesterova, Alistair E. T. Newall
Publikováno v:
Cell. 94(6)
Developmental regulation of the mouse Xist gene at the onset of X chromosome inactivation is mediated by RNA stabilization. Here, we show that alternate promoter usage gives rise to distinct stable and unstable RNA isoforms. Unstable Xist transcript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e507e804028928c05be5f5826183b7b8
https://pubmed.ncbi.nlm.nih.gov/9753327
https://pubmed.ncbi.nlm.nih.gov/9753327
Autor:
Gian-Carlo Alghisi, Sohaila Rastan, Neil Brockdorff, Sarah M. Duthie, Tatyana B. Nesterova, Emma J. Formstone, Alistair E. T. Newall, Steven A. Sheardown, Ruth M Arkell, Colette M. Johnston
Publikováno v:
Cell. 91(1)
The onset of X inactivation is preceded by a marked increase in the level of Xist RNA. Here we demonstrate that increased stability of Xist RNA is the primary determinant of developmental up-regulation. Unstable transcript is produced by both alleles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0e1128505894c59c2fd34d4d11337af
https://pubmed.ncbi.nlm.nih.gov/9335329
https://pubmed.ncbi.nlm.nih.gov/9335329