Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Colette Fong-Yee"'
Autor:
Sarah Kim, Holger Henneicke, Lauryn L. Cavanagh, Eugenie Macfarlane, Lee Joanne Thai, Daphne Foong, Sylvia J. Gasparini, Colette Fong-Yee, Michael M. Swarbrick, Markus J. Seibel, Hong Zhou
Publikováno v:
Bone Research, Vol 9, Iss 1, Pp 1-12 (2021)
Abstract Chronic high-fat diet (HFD) consumption not only promotes obesity and insulin resistance, but also causes bone loss through mechanisms that are not well understood. Here, we fed wild-type CD-1 mice either chow or a HFD (43% of energy from fa
Externí odkaz:
https://doaj.org/article/eb3abc04abc6414cb7fcf5ff0243655d
Autor:
Holger Henneicke, Sarah Kim, Michael M. Swarbrick, Jingbao Li, Sylvia J. Gasparini, Joanne Thai, Daphne Foong, Lauryn L. Cavanagh, Colette Fong-Yee, Elisabeth Karsten, Ruby C.Y. Lin, Mark S. Cooper, Hong Zhou, Markus J. Seibel
Publikováno v:
Molecular Metabolism, Vol 42, Iss , Pp 101098- (2020)
Objective: Aging and chronic glucocorticoid excess share a number of critical features, including the development of central obesity, insulin resistance and osteoporosis. Previous studies have shown that skeletal glucocorticoid signalling increases w
Externí odkaz:
https://doaj.org/article/476d489ea49a45f7a0699ebe4bb2d015
Autor:
Eugenie Macfarlane, Lauryn Cavanagh, Colette Fong-Yee, Jan Tuckermann, Di Chen, Christopher B. Little, Markus J. Seibel, Hong Zhou
Publikováno v:
Osteoarthritis and Cartilage.
Autor:
Hong Zhou, Sarah Kim, Colette Fong-Yee, Sylvia J. Gasparini, Lauryn L. Cavanagh, Lee Joanne Thai, Michael M. Swarbrick, Eugenie Macfarlane, Holger Henneicke, Markus J. Seibel, Daphne Foong
Publikováno v:
Bone Research
Bone Research, Vol 9, Iss 1, Pp 1-12 (2021)
Bone Research, Vol 9, Iss 1, Pp 1-12 (2021)
Chronic high-fat diet (HFD) consumption not only promotes obesity and insulin resistance, but also causes bone loss through mechanisms that are not well understood. Here, we fed wild-type CD-1 mice either chow or a HFD (43% of energy from fat) for 18
Autor:
Konstantin Horas, Colette Fong-Yee, Hong Zhou, Nancy Haydar, Markus J. Seibel, Peter I. Croucher, Eugenie Macfarlane, Jeline Manibo, Jeremy Qiao, Mingxuan Gao, Yu Zheng, Michelle M. McDonald, Yunzhao Chen
Publikováno v:
Journal of Bone and Mineral Research. 34:1721-1732
Expression of the vitamin D receptor (VDR) is thought to be associated with neoplastic progression. However, the role of the VDR in breast cancer metastasis to bone and the molecular mechanisms underlying this process are unknown. Employing a rodent
Autor:
Michael M. Swarbrick, Sylvia J. Gasparini, Mark S. Cooper, Holger Henneicke, Jingbao Li, Lauryn L. Cavanagh, Hong Zhou, Colette Fong-Yee, Markus J. Seibel, Elisabeth Karsten, Sarah Kim, Daphne Foong, Ruby C.Y. Lin, Joanne Thai
Publikováno v:
Molecular Metabolism, Vol 42, Iss, Pp 101098-(2020)
Molecular Metabolism
Molecular Metabolism
Objective Aging and chronic glucocorticoid excess share a number of critical features, including the development of central obesity, insulin resistance and osteoporosis. Previous studies have shown that skeletal glucocorticoid signalling increases wi
Autor:
Hong Zhou, Yu Zheng, Konstantin Horas, Musharraf Hossain, Ruby C.Y. Lin, Colette Fong-Yee, Colin R. Dunstan, Jeline Manibo, Rick Nolte, Yunzhao Chen, Markus J. Seibel, Trupti Trivedi
Publikováno v:
Bone Research
Vitamin D co-regulates cell proliferation, differentiation and apoptosis in numerous tissues, including cancers. The known anti-proliferative and pro-apoptotic actions of the active metabolite of vitamin D, 1,25-dihydroxy-vitamin D [1,25(OH)2D] are m
Autor:
Hong Zhou, Katja Boernert, Colin R. Dunstan, Yu Zheng, Colette Fong-Yee, Trupti Trivedi, Frank Buttgereit, Sarah Kim, Markus J. Seibel, Shu Oi Chow, Robert L. Sutherland, Dennis Basel, Anastasia Mikuscheva
Publikováno v:
Journal of Bone and Mineral Research. 29:1938-1949
The bone microenvironment and its modification by cancer and host cell interactions is a key driver of skeletal metastatic growth. Interleukin-6 (IL-6) stimulates receptor activator of NF-κB ligand (RANKL) expression in bone cells, and serum IL-6 le
Autor:
Hong Zhou, Colette Fong-Yee, Colin R. Dunstan, Markus J. Seibel, Robert Kalak, Wendy Mak, Janine Street, Yu Zheng
Publikováno v:
Development. 136:427-436
Glucocorticoids are important regulators of bone cell differentiation and mesenchymal lineage commitment. Using a cell-specific approach of osteoblast-targeted transgenic disruption of intracellular glucocorticoid signaling, we discovered a novel mol
Autor:
Hong Zhou, Colin R. Dunstan, Markus J. Seibel, Colette Fong-Yee, Sarah Kim, Shu-Oi Chow, Frank Buttgereit, Yu Zheng, Dennis Basel
Publikováno v:
Clinicalexperimental metastasis. 31(8)
In prostate cancer metastases to bone, cancer cell-derived cytokines stimulate RANKL expression by cells of the osteoblast lineage, which in turn activates osteoclastic bone resorption. However, it is unclear whether cells of the osteoblast lineage s