Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Colette Chaney"'
Autor:
Ted Gooley, Raphael Gottardo, Shivani Srivastava, Erin Mullane, Christoph Rader, Stanley R. Riddell, Carolina Berger, Robert H. Pierce, Sylvia Lee, David G. Maloney, V Viollet, Jennifer M. Specht, Cameron J. Turtle, Josh Veatch, Colette Chaney, A Balakrishnan
Publikováno v:
Cancer Research. 79:P2-09
BACKGROUND: ROR1 is a type 1 transmembrane tyrosine kinase receptor that plays a critical role in embryonic and fetal development. ROR1 has been described as a possible oncogene and is expressed in numerous malignancies including TNBC and non-small c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af523779784a1389637005f35e4b9833
https://doi.org/10.1158/1538-7445.sabcs18-p2-09-13
https://doi.org/10.1158/1538-7445.sabcs18-p2-09-13
Autor:
Marie Bleakley, Robson G. Dossa, Megan Hickner, Merav Bar, Tsadik Habtetsion, Melinda Ann Biernacki, Ann Dahlberg, Colette Chaney, Michelle Brault, Kyle B. Woodward, Nicole Vartanian, Tanya Cunningham, Corinne Summers, Elizabeth F. Krakow
Publikováno v:
Blood. 136:45-46
Background: Donor T cells specific for minor histocompatibility (H) antigens can deliver potent, selective anti-leukemic effects after allogeneic HCT when the antigen is negligibly or not expressed by non-hematopoietic tissues, not present in the don
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff0d542dde88d3fb0b34e7f4999abe70
https://doi.org/10.1182/blood-2020-137726
https://doi.org/10.1182/blood-2020-137726
Autor:
Barbara S. Pender, Shelly Heimfeld, Ted Gooley, Sindhu Cherian, Brent L. Wood, Xueyan Chen, Michael Hudecek, Emily Robinson, Colette Chaney, Cecilia Yeung, Katherine Melville, David G. Maloney, Stanley R. Riddell, Jianhong Cao, Lorinda Soma, Natalia N Steevens, Carolina Berger, Cameron J. Turtle, Daniel Sommermeyer, Tanya M Budiarto, Laïla Aïcha Hanafi, Michael C. Jensen, Daniel Li
Publikováno v:
Journal of Clinical Investigation. 126:2123-2138
BACKGROUND. T cells that have been modified to express a CD19-specific chimeric antigen receptor (CAR) have antitumor activity in B cell malignancies; however, identification of the factors that determine toxicity and efficacy of these T cells has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8449d6f7050567467136afa4c2f41e09
https://doi.org/10.1172/jci85309
https://doi.org/10.1172/jci85309
Autor:
Cameron J. Turtle, Susan Lemmon, Jeffrey Reitan, Grace Jones, Colette Chaney, Toni-Ann Lupinacci, David G. Maloney, Marion S. Dorer
Publikováno v:
Biology of Blood and Marrow Transplantation. 26:S385
Topic Significance & Study Purpose/Background/Rationale Immune effector cell (IEC) therapy is a rapidly changing scientific frontier. IEC therapies represent a significant novel opportunity to reduce morbidity and mortality of cancer. The complexity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2ba4d0227d109c5ef9ac4cc444cc4ba
https://doi.org/10.1016/j.bbmt.2019.12.142
https://doi.org/10.1016/j.bbmt.2019.12.142
Autor:
Xueyan Chen, Lorinda Soma, Carolina Berger, Reed M. Hawkins, Colette Chaney, Sindhu Cherian, Cameron J. Turtle, Laila-Aicha Hanafi, Brent L. Wood, David G. Maloney, Barbara S. Pender, Stanley R. Riddell, Michael Hudecek, Daniel Li, Shelly Heimfeld, Emily Robinson
CD19-specific chimeric antigen receptor (CAR)-modified T cells have antitumor activity in B cell malignancies, but factors that impact toxicity and efficacy have been difficult to define because of differences in lymphodepletion regimens and heteroge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a4c9b9e867c9e9d8f30880d2230323
https://europepmc.org/articles/PMC5045301/
https://europepmc.org/articles/PMC5045301/
Autor:
Ted Gooley, David G. Maloney, Sylvia Lee, Erin Mullane, Valentin Voillet, Ashwini Baladrishnan, Carolina Berger, Christoph Rader, Robert H. Pierce, Shivani Srivastava, Josh Veatch, Colette Chaney, Raphael Gottardo, Jennifer M. Specht, Stanley R. Riddell, Cameron J. Turtle
Publikováno v:
Cancer Research. 78:CT131-CT131
INTRODUCTION: ROR1 is a type 1 transmembrane tyrosine kinase receptor that plays a critical role in embryonic and fetal development. ROR1 has been described as a possible oncogene and is expressed in numerous malignancies, including a subset of non-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ae16970824e5b8248335cdc893406af
https://doi.org/10.1158/1538-7445.am2018-ct131
https://doi.org/10.1158/1538-7445.am2018-ct131
Autor:
Stanley R. Riddell, Marie Bleakley, Michael Hudecek, Julia L. Richardt, Audrey D. Mollerup, Mark Leppert, Edus H. Warren, Colette Chaney, Brith Otterud, Tetsuya Nishida
Publikováno v:
Blood. 115:4923-4933
T-cell immunotherapy that targets minor histocompatibility (H) antigens presented selectively by recipient hematopoietic cells, including leukemia, could prevent and treat leukemic relapse after hematopoietic cell transplantation without causing graf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c94d60868782273cff8be22d0792a48
https://doi.org/10.1182/blood-2009-12-260539
https://doi.org/10.1182/blood-2009-12-260539
Autor:
Erin Mullane, Stanley R. Riddell, Carolina Berger, Sylvia Lee, Jennifer M. Specht, Cameron J. Turtle, Josh Veatch, Colette Chaney, Ted Gooley, David G. Maloney
Publikováno v:
Journal of Clinical Oncology. 36:TPS79-TPS79
TPS79 Background: CAR-T cells have demonstrated marked tumor regression in patients (pts) with hematologic malignancies. ROR1, a tyrosine kinase orphan receptor, is expressed in triple negative breast cancers (TNBC) and non-small cell lung cancers (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f2fd872a965817f0744f86a52a9b8c2
https://doi.org/10.1200/jco.2018.36.5_suppl.tps79
https://doi.org/10.1200/jco.2018.36.5_suppl.tps79
Autor:
Shelly Heimfeld, Ted Gooley, Franziska Sommermeyer, Warren D. Shlomchik, Lori Jones, Stuart Seropian, Stanley R. Riddell, Marie Bleakley, Keith R. Loeb, Colette Chaney
Publikováno v:
The Journal of clinical investigation. 125(7)
BACKGROUND. Graft-versus-host disease (GVHD) is a major cause of morbidity and mortality following allogeneic hematopoietic stem cell transplantation (HCT). In mice, naive T cells (TN) cause more severe GVHD than memory T cells (TM). We hypothesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5028d0813e45b9e80b0aff2a66b8d8
https://pubmed.ncbi.nlm.nih.gov/26053664
https://pubmed.ncbi.nlm.nih.gov/26053664
Autor:
Cameron J. Turtle, Daniel Li, David G. Maloney, Laila-Aicha Hanafi, Shelly Heimfeld, Colette Chaney, Stanley R. Riddell
Publikováno v:
Blood. 128:56-56
BACKGROUND: Ibrutinib, a Bruton Tyrosine Kinase (BTK) inhibitor causes partial responses (PR) in a majority of patients (pts) with chronic lymphocytic leukemia (CLL). However, complete responses (CR) are rare and high-risk pts who progress on ibrutin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d9ce5ea550c57fd959997e4ec6b2cd7
https://doi.org/10.1182/blood.v128.22.56.56
https://doi.org/10.1182/blood.v128.22.56.56