Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Colette Broquet"'
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NEW ANTINEOPLASTIC AZA-PHOSPHOLIPIDS - SYNTHESIS, IN-VITRO CYTOTOXICITY AND DIFFERENTIAL CELLULAR-SENSITIVITY AGAINST 70 HUMAN TUMOR-CELL LINES
Autor: P. Braquet, Colette Broquet, Mencia-Huerta Jm, K Paull, H. Coulomb, Grever, M. Huchet, Principe P
Publikováno v: International Journal of Oncology. 4:29-36
The in vitro cytotoxicity and differential cellular sensitivity of three new synthetic anti-neoplastic aza-phospholipids has been determined in the National Cancer Institute's (NCI) primary antitumor drug screen. Based on a disease-oriented strategy,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::20d55f608d684db8b8cafe34ebc1c195
https://doi.org/10.3892/ijo.4.1.29
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3
Effect of paf antagonists on the cytotoxic activity of antineoplastic ether phospholipids
Autor: M. Salmona, M.T. Domingo, P. E. Chabrier, P Braquet, Colette Broquet, P. Principe, L. Diomede
Publikováno v: International journal of oncology. 2(5)
The capability of the methoxy-substituted 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (ET-18-OCH3 or Edelfosine) and the two aza-alkylphospholipids BN 52205 and BN 52211 to bind to the PAF receptor was analysed in rabbit platelet membranes.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1fa037acb3b232c37a37b32e7b5b6d5
https://pubmed.ncbi.nlm.nih.gov/21573625
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4
Sensitivity of drug-resistant B-cell lines from AIDS-related non-hodgkins-lymphoma to newly synthesized podophyllotoxin derivatives and aza-alkyllysophospholipids - enhanced sensitization by pretreatment with interferon-gamma
Autor: P. Braquet, Am Levine, A Demidem, Mencia-Huerta Jm, T Lam, Rs Khan, Benjamin Bonavida, Colette Broquet, Sz Salahuddin
Publikováno v: International journal of oncology. 4(6)
Non-Hodgkin's lymphoma B cells (NHL-B) often become refractory to conventional chemotherapeutic drugs. The present study investigated the sensitivity of three AIDS-derived NHL-B cell lines to newly synthesized azaalkyllysophospholipids (AALP) and pod
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794f604c12208a53e95c8e9a1bdfd15c
https://pubmed.ncbi.nlm.nih.gov/21567038
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5
CYTOTOXIC ACTIVITY AGAINST RESISTANT HUMAN TUMOR-CELL LINES BY 2 SYNTHETIC DEMETHYLPODOPHYLLOTOXIN DERIVATIVES - A SINGLE STEREOISOMERIC CHANGE PREVENTS CELL-DEATH BY APOPTOSIS
Autor: Morimoto H, Colette Broquet, Benjamin Bonavida, Jp Robin, Mencia-Huerta Jm, P. Braquet
Publikováno v: International Journal of Oncology. 3:1061-1066
The podophyllotoxin derivative, etoposide, is currently being used in patients with variant malignant diseases. However, studies show resistance to etoposide develops, and thus new agents to overcome resistance are needed. The present study investiga
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439dc9bc484ab3268b5ed3e1c5f0392f
https://doi.org/10.3892/ijo.3.6.1061
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7
Intravitreally injected platelet activating factor induces retinitis in experimental animals
Autor: Pierre Braquet, James T. Rosenbaum, Colette Broquet, David J. Wilson, Richard S. Boney, Ethan Angell
Publikováno v: Current eye research. 18(5)
Platelet activating factor is a lipid which has been strongly implicated in anterior uveitis. In order to investigate further the role of platelet activating factor in intraocular inflammation, we have characterized the histological changes associate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0d99c395d0401529d3c5b65605ec25
https://pubmed.ncbi.nlm.nih.gov/10372995
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8
Evaluation of combinations of antineoplastic ether phospholipids and chemotherapeutic drugs
Autor: Colette Broquet, Pierre Braquet, Paola Principe, H. Coulomb
Publikováno v: Anti-cancer drugs. 3(6)
Combinations of drugs are used clinically for the therapeutic advantages they may provide over single agents. We have studied the cytotoxic interaction between four either phospholipids ET-18-OCH3, BM 41.440, BN 52205 and BN 52211, and several chemot
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::187d0e0abaad37dddef86da8b08bc7c2
https://pubmed.ncbi.nlm.nih.gov/1288728
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9
Immunomodulatory activity of two new aza alkyl phospholipid antineoplastic drugs
Autor: Colette Broquet, H. Coulomb, B. Pignol, Chaumeron S, T. Maisonnet, B Vandamme, J. M. Mencia-Huerta, Pierre Braquet
Publikováno v: Anti-cancer drugs. 3(6)
The present work reports the modulation of immunocompetent cell functions by two aza alkyl phospholipids (AAP), BN 52205 and BN 52211. Each compound was compared with 1-O-octadecyl-2-O-rac-glycero-3-phosphocholine (ET-18-OCH3) and/or three drugs used
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14d1cc8ee7b734acc4aa94ff118ac37
https://pubmed.ncbi.nlm.nih.gov/1288731
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10
Cytostatic activity of new synthetic anti-tumor aza-alkyllysophospholipids
Autor: Paola Principe, Vandamme Benedicte, Pierre Braquet, Colette Broquet, Carole Sidoti
Publikováno v: International journal of cancer. 51(5)
Alkyllysophospholipids are analogues of the naturally occurring 2-lysophosphatidylcholine which have been reported to have selective in vitro/in vivo anti-tumor activity. Their anti-proliferative effect has been found against a variety of animal and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73941c2e373190ba50338f35142e7565
https://pubmed.ncbi.nlm.nih.gov/1612779
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