Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Colette A. Cote"'
Autor:
Ke Weng, S. Gary Mansfield, Marcelo Amar, Colette A. Cote, Gerard J McGarrity, Alan T. Remaley, Jun Wang, Mariano A. Garcia-Blanco, Madaiah Puttaraju, Ping Du Jiang, Bryan H. Brewer
Publikováno v:
Molecular Therapy. 17:343-351
Spliceosome-mediated RNA trans-splicing has emerged as an exciting mode of RNA therapy. Here we describe a novel trans-splicing strategy, which targets highly abundant pre-mRNAs, to produce therapeutic proteins in vivo. First, we used a pre-trans-spl
Autor:
Tracy L. Kress, Raymond A. Lewis, Denise Gautreau, Megan E. Rokop, Colette A. Cote, Kimberly L. Mowry
Publikováno v:
Mechanisms of Development. 121(1):101-109
Although it is widely regarded that the targeting of RNA molecules to subcellular destinations depends upon the recognition of ciselements found within their 3 0 untranslated regions (UTR), relatively little is known about the specific features of th
Autor:
Kimberly L. Mowry, Tracy L. Kress, James M. Denegre, Natalie A Terry, Colette A. Cote, Denise Gautreau
Publikováno v:
Molecular Cell. 4:431-437
Cytoplasmic localization of mRNA molecules is a powerful mechanism for generating cell polarity. In vertebrates, one paradigm is localization of Vg1 RNA within the Xenopus oocyte, a process directed by recognition of a localization element within the
Autor:
Colette A. Cote, Kimberly L. Mowry
Publikováno v:
The FASEB Journal. 13:435-445
Cytoplasmic localization of mRNA molecules has emerged as a powerful mechanism for generating spatially restricted gene expression. This process is an important contributor to cell polarity in both somatic cells and oocytes, and can provide the basis
Autor:
Jun Wang, Yanping Yang, Colette A. Cote, Edward Otto, Lloyd G. Mitchell, Weng Ke, S. Gary Mansfield, Garry P. Nolan, Jonathan E. Spindler, Madaiah Puttaraju
Publikováno v:
Molecular Therapy. 9:S271-S272
Spliceosome Mediated RNA Trans-splicing (SMaRT™) is a platform technology to reprogram genes at the pre-mRNA level. Applications include RNA therapy and real-time molecular imaging, with each application dependent upon the nature of the sequences e