Feasibility and application of polygenic score analysis to the morphology of human induced pluripotent stem cells

Autor: Coleman Jri

Genome-wide association studies have identified thousands of significant associations between genetic variants and complex traits. Inferring biological insights from these associations has been challenging. One approach attempted has been to examine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5da3a949c81b9d876e789e519d6a823f
https://doi.org/10.1101/2020.12.11.411314

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

Autor: Watson HJ, Yilmaz Z, Thornton LM, Hübel C, Coleman JRI, Gaspar HA, Bryois J, Hinney A, Leppä VM, Mattheisen M, Medland SE, Ripke S, Yao S, Giusti-Rodríguez P, Anorexia Nervosa Genetics Initiative, Hanscombe KB, Purves KL, Eating Disorders Working Group of the Psychiatric Genomics Consortium, Adan RAH, Alfredsson L, Ando T, Andreassen OA, Baker JH, Berrettini WH, Boehm I, Boni C, Perica VB, Buehren K, Burghardt R, Cassina M, Cichon S, Clementi M, Cone RD, Courtet P, Crow S, Crowley JJ, Danner UN, Davis OSP, de Zwaan M, Dedoussis G, Degortes D, DeSocio JE, Dick DM, Dikeos D, Dina C, Dmitrzak-Weglarz M, Docampo E, Duncan LE, Egberts K, Ehrlich S, Escaramís G, Esko T, Estivill X, Farmer A, Favaro A, Fernández-Aranda F, Fichter MM, Fischer K, Föcker M, Foretova L, Forstner AJ, Forzan M, Franklin CS, Gallinger S, Giegling I, Giuranna J, Gonidakis F, Gorwood P, Mayora MG, Guillaume S, Guo Y, Hakonarson H, Hatzikotoulas K, Hauser J, Hebebrand J, Helder SG, Herms S, Herpertz-Dahlmann B, Herzog W, Huckins LM, Hudson JI, Imgart H, Inoko H, Janout V, Jiménez-Murcia S, Julià A, Kalsi G, Kaminská D, Kaprio J, Karhunen L, Karwautz A, Kas MJH, Kennedy JL, Keski-Rahkonen A, Kiezebrink K, Kim YR, Klareskog L, Klump KL, Knudsen GPS, La Via MC, Le Hellard S, Levitan RD, Li D, Lilenfeld L, Lin BD, Lissowska J, Luykx J, Magistretti PJ, Maj M, Mannik K, Marsal S, Marshall CR, Mattingsdal M, McDevitt S, McGuffin P, Metspalu A, Meulenbelt I, Micali N, Mitchell K, Monteleone AM, Monteleone P, Munn-Chernoff MA, Nacmias B, Navratilova M, Ntalla I, O'Toole JK, Ophoff RA, Padyukov L, Palotie A, Pantel J, Papezova H, Pinto D, Raquel Rabionet Janssen, Raevuori A, Ramoz N, Reichborn-Kjennerud T, Ricca V, Ripatti S, Ritschel F, Roberts M, Rotondo A, Rujescu D, Rybakowski F, Santonastaso P, Scherag A, Scherer SW, Schmidt U, Schork NJ, Schosser A, Seitz J, Slachtova L, Slagboom PE, Slof-Op 't Landt MCT, Slopien A, Sorbi S, Swiatkowska B, Szatkiewicz JP, Tachmazidou I, Tenconi E, Tortorella A, Tozzi F, Treasure J, Tsitsika A, Tyszkiewicz-Nwafor M, Tziouvas K, van Elburg AA, van Furth EF, Wagner G, Walton E, Widen E, Zeggini E, Zerwas S, Zipfel S, Bergen AW, Boden JM, Brandt H, Crawford S, Halmi KA, Horwood LJ, Johnson C, Kaplan AS, Kaye WH, Mitchell JE, Olsen CM, Pearson JF, Pedersen NL, Strober M, Werge T, Whiteman DC, Woodside DB, Stuber GD, Gordon S, Grove J, Henders AK, Juréus A, Kirk KM, Larsen JT, Parker R, Petersen L, Jordan J, Kennedy M, Montgomery GW, Wade TD, Birgegård A, Lichtenstein P, Norring C, Landén M, Martin NG, Mortensen PB, Sullivan PF, Breen G, Bulik CM

Publikováno v: NATURE GENETICS
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu

Characterized primarily by a low body-mass index, anorexia nervosa is a complex and serious illness 1 , affecting 0.9-4% of women and 0.3% of men 2-4 , with twin-based heritability estimates of 50-60% 5 . Mortality rates are higher than those in othe

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http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=16446

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

Autor: Glanville, Kylie P, Coleman, Jonathan R I, Binder, Elisabeth B, Hall, Lynsey S, Hansen, Christine Søholm, Hansen, Thomas F, Herms, Stefan, Hickie, Ian B, Hoffmann, Per, Homuth, Georg, Horn, Carsten, Hottenga, Jouke-Jan, Hougaard, David M, Blackwood, Douglas H R, Howard, David M, Ising, Marcus, Jansen, Rick, Jones, Ian, Jones, Lisa A, Jorgenson, Eric, Knowles, James A, Kohane, Isaac S, Kraft, Julia, Kretzschmar, Warren W, Boomsma, Dorret I, Kutalik, Zoltán, Li, Yihan, Lind, Penelope A, MacIntyre, Donald J, MacKinnon, Dean F, Maier, Robert M, Maier, Wolfgang, Marchini, Jonathan, Mbarek, Hamdi, McGrath, Patrick, Buttenschøn, Henriette N, McGuffin, Peter, Medland, Sarah E, Mehta, Divya, Middeldorp, Christel M, Mihailov, Evelin, Milaneschi, Yuri, Milani, Lili, Mondimore, Francis M, Montgomery, Grant W, Mostafavi, Sara, Colodro-Conde, Lucía, Mullins, Niamh, Nauck, Matthias, Ng, Bernard, Nivard, Michel G, Nyholt, Dale R, O'Reilly, Paul F, Oskarsson, Hogni, Owen, Michael J, Painter, Jodie N, Pedersen, Carsten Bøcker, Dannlowski, Udo, Pedersen, Marianne Giørtz, Peterson, Roseann E, Pettersson, Erik, Peyrot, Wouter J, Pistis, Giorgio, Posthuma, Danielle, Quiroz, Jorge A, Qvist, Per, Rice, John P, Riley, Brien P, Direk, Nese, Rivera, Margarita, Mirza, Saira Saeed, Schoevers, Robert, Schulte, Eva C, Shen, Ling, Shi, Jianxin, Shyn, Stanley I, Sigurdsson, Engilbert, Sinnamon, Grant C B, Smit, Johannes H, Dunn, Erin C, Smith, Daniel J, Stefansson, Hreinn, Steinberg, Stacy, Streit, Fabian, Strohmaier, Jana, Tansey, Katherine E, Teismann, Henning, Teumer, Alexander, Thompson, Wesley, Thomson, Pippa A, Forstner, Andreas J, Thorgeirsson, Thorgeir E, Traylor, Matthew, Treutlein, Jens, Trubetskoy, Vassily, Uitterlinden, Andrés G, Umbricht, Daniel, Van der Auwera, Sandra, van Hemert, Albert M, Viktorin, Alexander, Visscher, Peter M, de Geus, Eco J C, Wang, Yunpeng, Webb, Bradley T, Weinsheimer, Shantel Marie, Wellmann, Jürgen, Willemsen, Gonneke, Witt, Stephanie H, Wu, Yang, Xi, Hualin S, Yang, Jian, Zhang, Futao, Hanscombe, Ken B, Grabe, Hans J, Arolt, Volker, Baune, Bernhard T, Berger, Klaus, Cichon, Sven, de Geus, E. J. C., DePaulo, J Raymond, Domenici, Enrico, Domschke, Katharina, Hamilton, Steven P, Esko, Tõnu, Hayward, Caroline, Heath, Andrew C, Kendler, Kenneth S, Kloiber, Stefan, Lewis, Glyn, Li, Qingqin S, Lucae, Susanne, Madden, Pamela Af, Magnusson, Patrik K, Martin, Nicholas G, McIntosh, Andrew M, Metspalu, Andres, Mors, Ole, Mortensen, Preben Bo, Müller-Myhsok, Bertram, Nordentoft, Merete, Nöthen, Markus M, O'Donovan, Michael C, Paciga, Sara A, Pedersen, Nancy L, Penninx, Brenda W J H, Perlis, Roy H, Porteous, David J, Potash, James B, Preisig, Martin, Rietschel, Marcella, Schaefer, Catherine, Schulze, Thomas G, Smoller, Jordan W, Stefansson, Kari, Tiemeier, Henning, Uher, Rudolf, Völzke, Henry, Weissman, Myrna M, Werge, Thomas, Lewis, Cathryn M, Levinson, Douglas F, Breen, Gerome, Børglum, Anders D, Sullivan, Patrick F, Euesden, Jack, Choi, Shing Wan, Ripke, Stephan, Purves, Kirstin L, Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics, Wray, Naomi R, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M, Abdellaoui, Abdel, Adams, Mark J, Agerbo, Esben, Air, Tracy M, Andlauer, Till F M, Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T F, Bigdeli, Tim B, Bryois, Julien, Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane Hvarregaard, Clarke, Toni-Kim, Couvy-Duchesne, Baptiste, Craddock, Nick, Crawford, Gregory E, Davies, Gail, Deary, Ian J, Degenhardt, Franziska, Derks, Eske M, Dolan, Conor V, Eley, Thalia C, Escott-Price, Valentina, Hassan Kiadeh, Farnush Farhadi, Finucane, Hilary K, Foo, Jerome C, Frank, Josef, Gaspar, Héléna A, Gill, Michael, Goes, Fernando S, Gordon, Scott D, Grove, Jakob

Publikováno v: Biological psychiatry, 87(5), 419-430. Elsevier USA
2019, ' Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression ', Biological Psychiatry . https://doi.org/10.1016/j.biopsych.2019.06.031
Biological psychiatry, vol. 87, no. 5, pp. 419-430
Glanville, K P, Lewis, C M, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A, Dolan, C V, Hottenga, J J, Jansen, R, Mbarek, H, Middeldorp, C M, Milaneschi, Y, Nivard, M G, Peyrot, W J, Posthuma, D & Willemsen, G 2020, ' Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression ', Biological Psychiatry, vol. 87, no. 5, pp. 419-430 . https://doi.org/10.1016/j.biopsych.2019.06.031
Biological Psychiatry, 87(5), 419-430. Elsevier USA
Biological Psychiatry
Online: 0006-3223
Biological Psychiatry, 87(5), 419-430. Elsevier Inc.
Glanville, K P, Coleman, J R I, Hanscombe, K B, Euesden, J, Choi, S W, Purves, K L, Breen, G, Air, T M, Andlauer, T F M, Baune, B T, Binder, E B, Blackwood, D H R, Boomsma, D I, Buttenschøn, H N, Colodro-Conde, L, Dannlowski, U, Direk, N, Dunn, E C, Forstner, A J, de Geus, E J C, Grabe, H J, Hamilton, S P, Jones, I, Jones, L A, Knowles, J A, Kutalik, Z, Levinson, D F, Lewis, G, Lind, P A, Lucae, S, Magnusson, P K, McGuffin, P, McIntosh, A M, Milaneschi, Y, Mors, O, Mostafavi, S, Müller-Myhsok, B, Pedersen, N L, Penninx, B W J H, Potash, J B, Preisig, M, Ripke, S, Shi, J, Shyn, S I, Smoller, J W, Streit, F, Sullivan, P F, Tiemeier, H, Uher, R, Van der Auwera, S & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2020, ' Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression ', Biological Psychiatry, vol. 87, no. 5, pp. 419-430 . https://doi.org/10.1016/j.biopsych.2019.06.031
Biological Psychiatry, 87(5), 419-430. ELSEVIER SCIENCE INC
Glanville, K P, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Coleman, J R I, Hanscombe, K B, Euesden, J, Choi, S W, Purves, K L, Breen, G, Air, T M, Andlauer, T F M, Baune, B T, Binder, E B, Blackwood, D H R, Boomsma, D I, Buttenschøn, H N, Colodro-Conde, L, Dannlowski, U, Direk, N, Dunn, E C, Forstner, A J, de Geus, E J C, Grabe, H J, Hamilton, S P, Jones, I, Jones, L A, Knowles, J A, Kutalik, Z, Levinson, D F, Lewis, G, Lind, P A, Lucae, S, Magnusson, P K, McGuffin, P, McIntosh, A M, Milaneschi, Y, Mors, O, Mostafavi, S, Müller-Myhsok, B, Pedersen, N L, Penninx, B W J H, Potash, J B, Preisig, M, Ripke, S, Beekman, A T F, Jansen, R, Middeldorp, C M, Peyrot, W J, Posthuma, D, Schoevers, R, Smit, J H, de Geus, E J C, Weissman, M M & O'Reilly, P F 2020, ' Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression ', Biological Psychiatry, vol. 87, no. 5, pp. 419-430 . https://doi.org/10.1016/j.biopsych.2019.06.031
Biological psychiatry 87(5), 419-430 (2020). doi:10.1016/j.biopsych.2019.06.031
Glanville, K P, Coleman, J R I, Hanscombe, K B, Euesden, J, Choi, S W, Purves, K L, Breen, G, Air, T M, Andlauer, T F M, Baune, B T, Binder, E B, Blackwood, D H R, Boomsma, D I, Buttenschøn, H N, Colodro-Conde, L, Dannlowski, U, Direk, N, Dunn, E C, Forstner, A J, de Geus, E J C, Grabe, H J, Hamilton, S P, Jones, I, Jones, L A, Knowles, J A, Kutalik, Z, Levinson, D F, Lewis, G, Lind, P A, Lucae, S, Magnusson, P K, McGuffin, P, McIntosh, A M, Milaneschi, Y, Mors, O, Mostafavi, S, Müller-Myhsok, B, Pedersen, N L, Penninx, B W J H, Potash, J B, Preisig, M, Ripke, S, Shi, J, Bækvad-Hansen, M, Hansen, C S, Hansen, T F, Pedersen, C B, Pedersen, M G, Nordentoft, M, Werge, T & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2020, ' Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression ', Biological Psychiatry, vol. 87, no. 5, pp. 419-430 . https://doi.org/10.1016/j.biopsych.2019.06.031
Glanville, K P, Coleman, J R I, Hanscombe, K B, Euesden, J, Choi, S W, Purves, K, Breen, G, Air, T M, Andlauer, T M F, Baune, B T, Binder, E B, Blackwood, D H R, Boomsma, D I, Buttenschøn, H N, Colodro-Conde, L, Dannlowski, U, Direk, N, Dunn, E C, Forstner, A J, de Geus, E J C, Grabe, H J, Hamilton, S P, Jones, I, Jones, L A, Knowles, J A, Kutalik, Z, Levinson, D F, Lewis, G, Lind, P A, Lucae, S, Lucae, S, Magnusson., P K E, McGuffin, P, McIntosh, A, Milaneschi, Y, Lewis, C M, Mostafavi, S, Muller-Myhsok, B, Pedersen, N L, Penninx, B W, Potash, J B, Preisig, M, Ripke, S, Shi, J, Shyn, S I, Smoller, J W, Streit, F, Sullivan, P F, Tiemeier, H, Uher, R, der Auwera, S V, Weissman, M M, O'Reilly, P F & Lewis, C M 2020, ' Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression ', Biological psychiatry, vol. 87, no. 5, pp. 419-430 . https://doi.org/10.1016/j.biopsych.2019.06.031

Background\ud \ud The prevalence of depression is higher in individuals with autoimmune diseases, but the mechanisms underlying the observed comorbidities are unknown. Shared genetic etiology is a plausible explanation for the overlap, and in this st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9782d526132cb79104890e64504600e7
https://pure.amc.nl/en/publications/classical-human-leukocyte-antigen-alleles-and-c4-haplotypes-are-not-significantly-associated-with-depression(84178d87-a771-42e3-acf1-26f4c561ab32).html

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Autor: Czamara, Darina, Eraslan, Gökçen, Page, Christian M., Lahti, Jari, Lahti-Pulkkinen, Marius, Hämäläinen, Esa, Kajantie, Eero, Laivuori, Hannele, Villa, Pia M., Reynolds, Rebecca M., Nystad, Wenche, Håberg, Siri E., London, Stephanie J., O’Donnell, Kieran J., Garg, Elika, Meaney, Michael J., Entringer, Sonja, Wadhwa, Pathik D., Buss, Claudia, Jones, Meaghan J., Lin, David T. S., MacIsaac, Julie L., Kobor, Michael S., Koen, Nastassja, Zar, Heather J., Koenen, Karestan C., Dalvie, Shareefa, Stein, Dan J., Kondofersky, Ivan, Müller, Nikola S., Theis, Fabian J., Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F. M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B., Blackwood, Douglas H. R., Bryois, Julien, Buttenschøn, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane Hvarregaard, Clarke, Toni-Kim, Coleman, Jonathan R. I., Colodro-Conde, Lucía, Couvy-Duchesne, Baptiste, Craddock, Nick, Crawford, Gregory E., Davies, Gail, Deary, Ian J., Degenhardt, Franziska, Derks, Eske M., Direk, Nese, Dolan, Conor V., Dunn, Erin C., Eley, Thalia C., Escott-Price, Valentina, Kiadeh, Farnush Farhadi Hassan, Finucane, Hilary K., Forstner, Andreas J., Frank, Josef, Gaspar, Héléna A., Gill, Michael, Goes, Fernando S., Gordon, Scott D., Grove, Jakob, Hall, Lynsey S., Hansen, Christine Søholm, Hansen, Thomas F., Herms, Stefan, Hickie, Ian B., Hoffmann, Per, Homuth, Georg, Horn, Carsten, Hottenga, Jouke-Jan, Hougaard, David M., Ising, Marcus, Jansen, Rick, Jorgenson, Eric, Knowles, James A., Kohane, Isaac S., Kraft, Julia, Kretzschmar, Warren W., Krogh, Jesper, Kutalik, Zoltán, Li, Yihan, Lind, Penelope A., MacIntyre, Donald J., MacKinnon, Dean F., Maier, Robert M., Maier, Wolfgang, Marchini, Jonathan, Mbarek, Hamdi, McGrath, Patrick, McGuffin, Peter, Medland, Sarah E., Mehta, Divya, Middeldorp, Christel M., Mihailov, Evelin, Milaneschi, Yuri, Milani, Lili, Mondimore, Francis M., Montgomery, Grant W., Mostafavi, Sara, Mullins, Niamh, Nauck, Matthias, Ng, Bernard, Nivard, Michel G., Nyholt, Dale R., O’Reilly, Paul F., Oskarsson, Hogni, Owen, Michael J., Painter, Jodie N., Pedersen, Carsten Bøcker, Pedersen, Marianne Giørtz, Peterson, Roseann E., Pettersson, Erik, Peyrot, Wouter J., Pistis, Giorgio, Posthuma, Danielle, Quiroz, Jorge A., Qvist, Per, Rice, John P., Riley, Brien P., Rivera, Margarita, Mirza, Saira Saeed, Schoevers, Robert, Schulte, Eva C., Shen, Ling, Shi, Jianxin, Shyn, Stanley I., Sigurdsson, Engilbert, Sinnamon, Grant C. B., Smit, Johannes H., Smith, Daniel J., Stefansson, Hreinn, Steinberg, Stacy, Streit, Fabian, Strohmaier, Jana, Tansey, Katherine E., Teismann, Henning, Teumer, Alexander, Thompson, Wesley, Thomson, Pippa A., Thorgeirsson, Thorgeir E., Traylor, Matthew, Treutlein, Jens, Trubetskoy, Vassily, Uitterlinden, André G., Umbricht, Daniel, Van der Auwera, Sandra, van Hemert, Albert M., Viktorin, Alexander, Visscher, Peter M., Wang, Yunpeng, Webb, Bradley T., Weinsheimer, Shantel Marie, Wellmann, Jürgen, Willemsen, Gonneke, Witt, Stephanie H., Wu, Yang, Xi, Hualin S., Yang, Jian, Zhang, Futao, Arolt, Volker, Baune, Bernhard T., Berger, Klaus, Boomsma, Dorret I., Cichon, Sven, Dannlowski, Udo, de Geus, E. J. C., DePaulo, J. Raymond, Domenici, Enrico, Domschke, Katharina, Esko, Tõnu, Grabe, Hans J., Hamilton, Steven P., Hayward, Caroline, Heath, Andrew C., Kendler, Kenneth S., Kloiber, Stefan, Lewis, Glyn, Li, Qingqin S., Lucae, Susanne, Madden, Pamela A. F., Magnusson, Patrik K., Martin, Nicholas G., McIntosh, Andrew M., Metspalu, Andres, Mors, Ole, Mortensen, Preben Bo, Müller-Myhsok, Bertram, Nordentoft, Merete, Nöthen, Markus M., O’Donovan, Michael C., Paciga, Sara A., Pedersen, Nancy L., Penninx, Brenda W. J. H., Perlis, Roy H., Porteous, David J., Potash, James B., Preisig, Martin, Rietschel, Marcella, Schaefer, Catherine, Schulze, Thomas G., Smoller, Jordan W., Stefansson, Kari, Tiemeier, Henning, Uher, Rudolf, Völzke, Henry, Weissman, Myrna M., Werge, Thomas, Lewis, Cathryn M., Levinson, Douglas F., Breen, Gerome, Børglum, Anders D., Sullivan, Patrick F., Räikkönen, Katri, Binder, Elisabeth B., Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics

Publikováno v: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2019, ' Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns ', Nature Communications, vol. 10, no. 1, 2548 . https://doi.org/10.1038/s41467-019-10461-0
University of Queensland 2019, ' Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns ', Nature Communications, vol. 10, no. 1, 2548, pp. 1-18 . https://doi.org/10.1038/s41467-019-10461-0
Nature Communications, 10:2548. Nature Publishing Group
Nature Communications
Czamara, D, Eraslan, G K, Page, C M, Lahti, J, Lahti-Pulkkinen, M, Hämäläinen, E, Kajantie, E, Laivuori, H, Villa, P M, Reynolds, R M, Nystad, W, Håberg, S E, London, S J, O’Donnell, K J, Garg, E, Meaney, M J, Entringer, S, Wadhwa, P D, Buss, C, Jones, M J, Lin, D T S, MacIsaac, J L, Kobor, M S, Koen, N, Zar, H J, Koenen, K C, Dalvie, S, Stein, D J, Kondofersky, I, Müller, N S, Beekman, A T F, Jansen, R, Middeldorp, C M, Milaneschi, Y, Peyrot, W J, Schoevers, R, Smit, J H, de Geus, E J C, Penninx, B W J H, Posthuma, D, Smit, J H, Theis, F J, Räikkönen, K, Binder, E B & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2019, ' Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns ', Nature Communications, vol. 10, no. 1, 2548 . https://doi.org/10.1038/s41467-019-10461-0
Nature Communications, 10(1):2548. Nature Publishing Group
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Nature Communications, 10(1):2548, 1-18. Nature Publishing Group
NATURE COMMUNICATIONS
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Nature communications, 10(1):2548. Nature Publishing Group
Czamara, D, Eraslan, G, Page, C M, Lahti, J, Lahti-Pulkkinen, M, Hämäläinen, E, Kajantie, E, Laivuori, H, Villa, P M, Reynolds, R M, Nystad, W, Håberg, S E, London, S J, O'Donnell, K J, Garg, E, Meaney, M J, Entringer, S, Wadhwa, P D, Buss, C, Jones, M J, Lin, D T S, MacIsaac, J L, Kobor, M S, Koen, N, Zar, H J, Koenen, K C, Dalvie, S, Stein, D J, Kondofersky, I, Müller, N S, Theis, F J, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Räikkönen, K & Binder, E B 2019, ' Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns ', Nature Communications, vol. 10, 2548 . https://doi.org/10.1038/s41467-019-10461-0
Nature Communications 10(1), 2548 (2019). doi:10.1038/s41467-019-10461-0
Czamara, D, Abdellaoui, A, Beekman, A T F, Derks, E M, Dolan, C V, Hottenga, J J, Jansen, R, Mbarek, H, Middeldorp, C M, Milaneschi, Y, Nivard, M G, Posthuma, D, Boomsma, D I, Penninx, B W J H, Binder, E B & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2019, ' Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns ', Nature Communications, vol. 10, no. 1, 2548, pp. 1-18 . https://doi.org/10.1038/s41467-019-10461-0
Czamara, D, Eraslan, G, Page, C M, Lahti, J, Lahti-Pulkkinen, M, Hämäläinen, E, Kajantie, E, Laivuori, H, Villa, P M, Reynolds, R M, Nystad, W, Håberg, S E, London, S J, O’Donnell, K J, Garg, E, Meaney, M J, Entringer, S, Wadhwa, P D, Buss, C, Jones, M J, Lin, D T S, MacIsaac, J L, Kobor, M S, Koen, N, Zar, H J, Koenen, K C, Dalvie, S, Stein, D J, Kondofersky, I, Müller, N S, Theis, F J, Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T F M, Bacanu, S-A, Bækvad-Hansen, M, Beekman, A T F, Bigdeli, T B, Blackwood, D H R, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J H, Clarke, T-K, Coleman, J R I, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, Direk, N, Dolan, C V, Dunn, E C, Eley, T C, Escott-Price, V, Kiadeh, F F H, Finucane, H K, Forstner, A J, Frank, J, Gaspar, H A, Gill, M, Goes, F S, Gordon, S D, Grove, J, Hall, L S, Hansen, C S, Hansen, T F, Herms, S, Hickie, I B, Hoffmann, P, Homuth, G, Horn, C, Hottenga, J-J, Hougaard, D M, Ising, M, Jansen, R, Jorgenson, E, Knowles, J A, Kohane, I S, Kraft, J, Kretzschmar, W W, Krogh, J, Kutalik, Z, Li, Y, Lind, P A, MacIntyre, D J, MacKinnon, D F, Maier, R M, Maier, W, Marchini, J, Mbarek, H, McGrath, P, McGuffin, P, Medland, S E, Mehta, D, Middeldorp, C M, Mihailov, E, Milaneschi, Y, Milani, L, Mondimore, F M, Montgomery, G W, Mostafavi, S, Mullins, N, Nauck, M, Ng, B, Nivard, M G, Nyholt, D R, O’Reilly, P F, Oskarsson, H, Owen, M J, Painter, J N, Pedersen, C B, Pedersen, M G, Peterson, R E, Pettersson, E, Peyrot, W J, Pistis, G, Posthuma, D, Quiroz, J A, Qvist, P, Rice, J P, Riley, B P, Rivera, M, Mirza, S S, Schoevers, R, Schulte, E C, Shen, L, Shi, J, Shyn, S I, Sigurdsson, E, Sinnamon, G C B, Smit, J H, Smith, D J, Stefansson, H, Steinberg, S, Streit, F, Strohmaier, J, Tansey, K E, Teismann, H, Teumer, A, Thompson, W, Thomson, P A, Thorgeirsson, T E, Traylor, M, Treutlein, J, Trubetskoy, V, Uitterlinden, A G, Umbricht, D, Van der Auwera, S, van Hemert, A M, Viktorin, A, Visscher, P M, Wang, Y, Webb, B T, Weinsheimer, S M, Wellmann, J, Willemsen, G, Witt, S H, Wu, Y, Xi, H S, Yang, J, Zhang, F, Arolt, V, Baune, B T, Berger, K, Boomsma, D I, Cichon, S, Dannlowski, U, de Geus, E J C, DePaulo, J R, Domenici, E, Domschke, K, Esko, T, Grabe, H J, Hamilton, S P, Hayward, C, Heath, A C, Kendler, K S, Kloiber, S, Lewis, G, Li, Q S, Lucae, S, Madden, P A F, Magnusson, P K, Martin, N G, McIntosh, A M, Metspalu, A, Mors, O, Mortensen, P B, Müller-Myhsok, B, Nordentoft, M, Nöthen, M M, O’Donovan, M C, Paciga, S A, Pedersen, N L, Penninx, B W J H, Perlis, R H, Porteous, D J, Potash, J B, Preisig, M, Rietschel, M, Schaefer, C, Schulze, T G, Smoller, J W, Stefansson, K, Tiemeier, H, Uher, R, Völzke, H, Weissman, M M, Werge, T, Lewis, C M, Levinson, D F, Breen, G, Børglum, A D, Sullivan, P F, Räikkönen, K, Binder, E B & Consortium, M D D W G O T P G 2019, ' Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns ', Nature Communications, vol. 10, no. 1, 2548 . https://doi.org/10.1038/s41467-019-10461-0
Nature communications, vol 10, iss 1
Nature communications, vol. 10, no. 1, pp. 2548

Publisher's version (útgefin grein)
Epigenetic processes, including DNA methylation (DNAm), are among the mechanisms allowing integration of genetic and environmental factors to shape cellular function. While many studies have investigated eith

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Fine-mapping genomic loci refines bipolar disorder risk genes.

Autor: Koromina M; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Ravi A; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Estelle and Daniel Maggin Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Panagiotaropoulou G; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany., Schilder BM; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Estelle and Daniel Maggin Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Humphrey J; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Estelle and Daniel Maggin Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Braun A; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany., Bidgeli T; SUNY Downstate Health Sciences University., Chatzinakos C; SUNY Downstate Health Sciences University., Coombes B; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Kim J; Samsung Advanced Institute for Health Sciences and Technology (SAIHST), Sungkyunkwan University, Samsung Medical Center, Seoul, Republic of Korea.; Samsung Genome Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea., Liu X; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Clinical Research Center, Shizuoka General Hospital, Shizuoka, Japan., Terao C; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Clinical Research Center, Shizuoka General Hospital, Shizuoka, Japan.; The Department of Applied Genetics, The School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan., O 'Connell KS; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; NORMENT, University of Oslo, Oslo, Norway., Adams M; Division of Psychiatry, Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, UK., Rolf A; Department of Clinical Sciences, Psychiatry, Umeå, University Medical Faculty, Umeå, Sweden., Alda M; Department of Psychiatry, Dalhousie University, Halifax, NS, Canada.; National Institute of Mental Health, Klecany, Czech Republic., Alfredsson L; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Andlauer TFM; Department of Neurology, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany., Andreassen OA; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; NORMENT, University of Oslo, Oslo, Norway., Antoniou A; National Kapodistrian University of Athens, 2nd Department of Psychiatry, Attikon General Hospital, Athens, Greece., Baune BT; Department of Psychiatry, University of Münster, Münster, Germany.; Department of Psychiatry, Melbourne Medical School, The University of Melbourne, Melbourne, VIC, Australia.; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, Australia., Bengesser S; Medical University of Graz, Division of Psychiatry and Psychotherapeutic Medicine, Graz, Austria., Biernacka J; Department of Quantitative Health Sciences Research, Mayo Clinic, Rochester, MN, USA.; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA., Boehnke M; Center for Statistical Genetics and Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA., Bosch R; Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain.; Programa SJD MIND Escoles, Hospital Sant Joan de Déu, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Spain., Cairns MJ; University of Newcastle, Newcastle, NSW, Australia., Carr VJ; School of Clinical Medicine, Discipline of Psychiatry and Mental Health, University of New South Wales, Sydney, NSW, Australia., Casas M; Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain.; Programa SJD MIND Escoles, Hospital Sant Joan de Déu, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Spain., Catts S; University of Queensland, Brisbane, QLD, Australia., Cichon S; Department of Biomedicine, University of Basel, Basel, Switzerland.; Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.; Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany., Corvin A; Neuropsychiatric Genetics Research Group, Dept of Psychiatry and Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland., Craddock N; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Dafnas K; National Kapodistrian University of Athens, 2nd Department of Psychiatry, Attikon General Hospital, Athens, Greece., Dalkner N; Medical University of Graz, Division of Psychiatry and Psychotherapeutic Medicine, Graz, Austria., Dannlowski U; Institute for Translational Psychiatry, University of Münster, Münster, Germany., Degenhardt F; Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Duisburg, Germany., Florio AD; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.; Department of Psychiatry, University of North Caroli at Chapel Hill, Chapel Hill, NC, USA., Dikeos D; National Kapodistrian University of Athens, 2nd Department of Psychiatry, Attikon General Hospital, Athens, Greece., Fellendorf FT; Medical University of Graz, Division of Psychiatry and Psychotherapeutic Medicine, Graz, Austria., Ferentinos P; National Kapodistrian University of Athens, 2nd Department of Psychiatry, Attikon General Hospital, Athens, Greece.; Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK., Forstner AJ; Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.; Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.; Centre for Human Genetics, University of Marburg, Marburg, Germany., Forty L; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Frye M; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA., Fullerton JM; Neuroscience Research Australia, Sydney, NSW, Australia.; School of Biomedical Sciences, Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, Australia., Gawlik M; Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital Würzburg, Würzburg, Germany., Gizer IR; Department of Psychological Sciences, University of Missouri, Columbia, MO, USA., Gordon-Smith K; Psychological Medicine, University of Worcester, Worcester, UK., Green MJ; Neuroscience Research Australia, Sydney, NSW, Australia.; Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, Australia., Grigoroiu-Serbanescu M; Biometric Psychiatric Genetics Research Unit, Alexandru Obregia Clinical Psychiatric Hospital, Bucharest, Romania., Guzman-Parra J; Mental Health Department, University Regional Hospital, Biomedicine Institute (IBIMA), Málaga, Spain., Hahn T; Institute for Translational Psychiatry, University of Münster, Münster, Germany., Henskens F; University of Newcastle, Newcastle, NSW, Australia., Hillert J; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden., Jablensky AV; University of Western Australia, Nedlands, WA, Australia., Jones L; Psychological Medicine, University of Worcester, Worcester, UK., Jones I; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Jonsson L; Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden., Kelsoe JR; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA., Kircher T; Department of Psychiatry and Psychotherapy, University of Marburg, Germany., Kirov G; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Kittel-Schneider S; Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital Würzburg, Würzburg, Germany.; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany.; Department of Psychiatry and Neurobehavioural Science, University College Cork, Cork, Ireland., Kogevinas M; ISGlobal, Barcelona, Spain., Landén M; Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Leboyer M; University of Paris Est Créteil, INSERM, IMRB, Translatiol Neuropsychiatry, Créteil, France.; Department of Psychiatry and Addiction Medicine, Assistance Publique - Hôpitaux de Paris, Paris, France., Lenger M; Medical University of Graz, Division of Psychiatry and Psychotherapeutic Medicine, Graz, Austria., Lissowska J; Cancer Epidemiology and Prevention, M. Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland., Lochner C; SA MRC Unit on Risk and Resilience in Mental Disorders, Dept of Psychiatry, Stellenbosch University, Stellenbosch, South Africa., Loughland C; University of Newcastle, Newcastle, NSW, Australia., MacIntyre D; Division of Psychiatry, Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, UK., Martin NG; Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.; School of Psychology, The University of Queensland, Brisbane, QLD, Australia., Maratou E; National and Kapodistrian University of Athens, Medical School, Clinical Biochemistry Laboratory, Attikon General Hospital, Athens, Greece., Mathews CA; Department of Psychiatry and Genetics Institute, University of Florida, Gainesville, FL, USA., Mayoral F; Mental Health Department, University Regional Hospital, Biomedicine Institute (IBIMA), Málaga, Spain., McElroy SL; Research Institute, Lindner Center of HOPE, Mason, OH, USA., McGregor NW; Systems Genetics Working Group, Department of Genetics, Stellenbosch University, Stellenbosch, South Africa., McIntosh A; Division of Psychiatry, Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, UK., McQuillin A; Division of Psychiatry, University College London, London, UK., Michie P; University of Newcastle, Newcastle, NSW, Australia., Mitchell PB; Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, Australia., Moutsatsou P; National Kapodistrian University of Athens, Medical School, Clinical Biochemistry Laboratory, Attikon General Hospital, Athens, Greece., Mowry B; University of Queensland, Brisbane, QLD, Australia., Müller-Myhsok B; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Myers RM; Hudsolpha Institute for Biotechnology, Huntsville, AL, USA., Nenadić I; Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany.; Center for Mind, Brain and Behavior (CMBB), University of Marburg and Justus Liebig University Giessen, Giessen, Germany., Nievergelt C; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.; Research/Psychiatry, Veterans Affairs San, Diego Healthcare System, San Diego, CA, USA., Nöthen MM; Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany., Nurnberger J; Stark Neurosciences Research Institute, Indiana University School of Medicine.; Departments of Psychiatry and Medical and Molecular Genetics, Indiana University School of Medicine.; Indiana University School of Medicine., O 'Donovan M; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., O'Donovan C; Department of Psychiatry, Dalhousie University, Halifax, NS, Canada., Ophoff RA; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.; Department of Psychiatry and Biobehavioral Science, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Owen MJ; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Pantelis C; Department of Psychiatry, University of Melbourne, VIC, Australia., Pato C; Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, Brooklyn, NY, USA., Pato MT; Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, Brooklyn, NY, USA., Patrinos GP; University of Patras, School of Health Sciences, Department of Pharmacy, Laboratory of Pharmacogenomics and Individualized Therapy, Patras, Greece.; United Arab Emirates University, College of Medicine and Health Sciences, Department of Genetics and Genomics, Al-Ain, United Arab Emirates.; United Arab Emirates University, Zayed Center for Health Sciences, Al-Ain, United Arab Emirates.; Erasmus University Medical Center, Faculty of Medicina and Health Sciences, Department of Pathology, Clinical Bioinformatics Unit, Rotterdam, The Netherlands., Pawlak JM; Department of Psychiatry, Departmet of Psychiatric Genetics, Poznan University of Medical Sciences, Poznan, Poland., Perlis RH; Psychiatry, Harvard Medical School, Boston, MA, USA.; Division of Clinical Research, Massachusetts General Hospital, Boston, MA, USA., Porichi E; tiol and Kapodistrian University of Athens, 2nd Department of Psychiatry, Attikon General Hospital, Athens, Greece., Posthuma D; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Department of Clinical Genetics, Amsterdam Neuroscience, Vrije Universiteit Medical Center, Amsterdam, The Netherlands., Ramos-Quiroga JA; Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain.; Department of Psychiatry, Hospital Universitari Vall d´Hebron, Barcelona, Spain.; Department of Psychiatry and Forensic Medicine, Universitat Autònoma de Barcelo, Barcelo, Spain.; Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall d´Hebron Research Institut (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain., Reif A; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany., Reininghaus EZ; Medical University of Graz, Division of Psychiatry and Psychotherapeutic Medicine, Graz, Austria., Ribasés M; Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain.; Department of Psychiatry, Hospital Universitari Vall d´Hebron, Barcelona, Spain.; Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall d´Hebron Research Institut (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.; Department of Genetics, Microbiology, and Statistics, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain. Department of Genetics, Microbiology and Statistics, Faculty of Biology, Universitat de Barcelona, Barcelona, Catalonia, Spain., Rietschel M; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Schall U; University of Newcastle, Newcastle, NSW, Australia., Schofield PR; Neuroscience Research Australia, Sydney, NSW, Australia.; School of Biomedical Sciences, Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, Australia., Schulze TG; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany.; Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, NY, USA., Scott L; Center for Statistical Genetics and Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA., Scott RJ; University of Newcastle, Newcastle, NSW, Australia., Serretti A; Department of Medicine and Surgery, Kore University of Enna, Italy.; Oasi Research Institute-IRCCS, Troina, Italy., Weickert CS; Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, Australia.; Department of Neuroscience, SUNY Upstate Medical University, Syracuse, NY, USA., Smoller JW; Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA.; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit (PNGU), Massachusetts General Hospital, Boston, MA, USA., Artigas MS; Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain.; Department of Psychiatry, Hospital Universitari Vall d´Hebron, Barcelo, Spain.; Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall d´Hebron Research Institut (VHIR), Universitat Autònoma de Barcelo, Barcelo, Spain.; Department of Genetics, Microbiology, and Statistics, Faculty of Biology, Universitat de Barcelo, Barcelo, Spain. Department of Genetics, Microbiology and Statistics, Faculty of Biology, Universitat de Barcelo, Barcelo, Catalonia, Spain., Stein DJ; SAMRC Unit on Risk and Resilience in Mental Disorders, Dept of Psychiatry and Neuroscience Institute, University of Cape Town, Cape Town, South Africa., Streit F; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Hector Institute for Artificial Intelligence in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; German Center for Mental Health (DZPG), partner site Mannheim/Heidelberg/Ulm, Germany., Toma C; Neuroscience Research Australia, Sydney, NSW, Australia.; Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, Australia.; Centro de Biología Molecular Severo Ochoa, Universidad Autónoma de Madrid and CSIC, Madrid, Spain., Tooney P; University of Newcastle, Newcastle, NSW, Australia., Vawter MP; Functional Genomics Laboratory, School of Medicine, University of California, Irvine Canada.; Department of Psychiatry and Human Behavior, School of Medicine, University of California, Irvine Canada., Vieta E; Clinical Institute of Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain., Vincent JB; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada., Waldman ID; Department of Psychology, Emory University, Atlanta, GA, USA., Weickert T; Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, Australia.; Department of Neuroscience, SUNY Upstate Medical University, Syracuse, NY, USA., Witt SH; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Hong KS; Department of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada., Ikeda M; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan., Iwata N; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan., Świątkowska B; Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Lodz, Poland., Won HH; Samsung Advanced Institute for Health Sciences and Technology (SAIHST), Sungkyunkwan University, Samsung Medical Center, Seoul, Republic of Korea., Edenberg HJ; Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Medical and Molecular Genetics, Indiana University, Indianapolis, IN, USA., Ripke S; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA., Raj T; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Estelle and Daniel Maggin Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Coleman JRI; Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK.; NIHR Maudsley Biomedical Research Centre, South London and Maudsley NHS Foundation Trust, London, UK., Mullins N; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Sep 17. Date of Electronic Publication: 2024 Sep 17.