Zobrazeno 1 - 10
of 172
pro vyhledávání: '"Coleen A McNamara"'
Autor:
Nicole M Gilbertson, Julian M Gaitán, Victoria Osinski, Elizabeth A Rexrode, James C Garmey, J Hunter Mehaffey, Taryn E Hassinger, Sibylle Kranz, Coleen A McNamara, Arthur Weltman, Peter T Hallowell, Steven K Malin
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0239130 (2020)
ObjectiveExamine if adding aerobic exercise to standard medical care (EX+SC) prior to bariatric surgery improves metabolic health in relation to surgical outcomes.MethodsFourteen bariatric patients (age: 42.3±2.5y, BMI: 45.1±2.5 kg/m2) met inclusio
Externí odkaz:
https://doaj.org/article/21b53c46a88f40aa81765d4933088b2b
Autor:
Dustin K Bauknight, Victoria Osinski, Siva Sai Krishna Dasa, Anh T Nguyen, Melissa A Marshall, Julia Hartman, Matthew Harms, Gavin O'Mahony, Jeremie Boucher, Alexander L Klibanov, Coleen A McNamara, Kimberly A Kelly
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224917 (2019)
Targeted nanoparticle delivery is a promising strategy for increasing efficacy and limiting side effects of therapeutics. When designing a targeted liposomal formulation, the in vivo biodistribution of the particles must be characterized to determine
Externí odkaz:
https://doaj.org/article/2da99baf72954ed7b9b321d93ecc7b32
Autor:
Melissa D. Lempicki, Jake A. Gray, Gabriel Abuna, Ramiro M. Murata, Senad Divanovic, Coleen A. McNamara, Akshaya K. Meher
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
B cell-activating factor (BAFF) is a critical TNF-family cytokine that regulates homeostasis and peripheral tolerance of B2 cells. BAFF overproduction promotes autoantibody generation and autoimmune diseases. During obesity, BAFF is predominantly pro
Externí odkaz:
https://doaj.org/article/35503957c9b04965b4f3a57a5a6b6011
Autor:
Ani Manichaikul, Stephen S Rich, Heather Perry, Joseph Yeboah, Michelle Law, Molly Davis, Matthew Parker, Michael Ragosta, Jessica J Connelly, Coleen A McNamara, Angela M Taylor
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90222 (2014)
AIMS:We previously identified association between the ID3 SNP rs11574 and carotid intima-media thickness in the Diabetes Heart Study, a predominantly White diabetic population. The nonsynonymous SNP rs11574 results in an amino acid substitution in th
Externí odkaz:
https://doaj.org/article/3bae6df22156477eb4d7bf8f07e8f80b
Autor:
Soo-Ho Choi, Huiyong Yin, Amir Ravandi, Aaron Armando, Darren Dumlao, Jungsu Kim, Felicidad Almazan, Angela M Taylor, Coleen A McNamara, Sotirios Tsimikas, Edward A Dennis, Joseph L Witztum, Yury I Miller
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83145 (2013)
Oxidation of low-density lipoprotein (LDL) is one of the major causative mechanisms in the development of atherosclerosis. In previous studies, we showed that minimally oxidized LDL (mmLDL) induced inflammatory responses in macrophages, macropinocyto
Externí odkaz:
https://doaj.org/article/87ed55eeade74fe9a898dce0658d1287
Autor:
Emily Dennis, Maria Murach, Cassidy M.R. Blackburn, Melissa Marshall, Katherine Root, Tanyaporn Pattarabanjird, Justine Deroissart, Loren D. Erickson, Christoph J. Binder, Stefan Bekiranov, Coleen A. McNamara
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Recent studies have demonstrated a role for Ten-Eleven Translocation-2 (TET2), an epigenetic modulator, in regulating germinal center formation and plasma cell differentiation in B-2 cells, yet the role of TET2 in regulating B-1 cells is largely unkn
Externí odkaz:
https://doaj.org/article/e381fe19acd54eb697d2fdd0ef3acea1
Autor:
Tanyaporn Pattarabanjird, Prasad Srikakulapu, Brett Ransegnola, Melissa A. Marshall, Yanal Ghosheh, Rishab Gulati, Chistopher Durant, Fabrizio Drago, Angela M. Taylor, Klaus Ley, Coleen A. McNamara
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Circulating CD11c+ B cells, a novel subset of activated B cells, have been linked to autoimmunity and shown to expand with age. Atherosclerosis is an age-associated disease that involves innate and adaptive immune responses to modified self-antigens.
Externí odkaz:
https://doaj.org/article/23739574c08e4bf5bfb98dbb49e99b34
Autor:
Nandini Chatterjee, Ravi K. Komaravolu, Christopher P. Durant, Runpei Wu, Chantel McSkimming, Fabrizio Drago, Sunil Kumar, Gabriel Valentin-Guillama, Yury I. Miller, Coleen A. McNamara, Klaus Ley, Angela Taylor, Ahmad Alimadadi, Catherine C. Hedrick
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2894 (2024)
Monocytes are associated with human cardiovascular disease progression. Monocytes are segregated into three major subsets: classical (cMo), intermediate (iMo), and nonclassical (nMo). Recent studies have identified heterogeneity within each of these
Externí odkaz:
https://doaj.org/article/d65c30b4e2994c06bcbc7392a8e0b48f
Autor:
Payel Roy, John Sidney, Cecilia S. Lindestam Arlehamn, Elizabeth Phillips, Simon Mallal, Sujit Silas Armstrong Suthahar, Monica Billitti, Paul Rubiro, Daniel Marrama, Fabrizio Drago, Jenifer Vallejo, Vasantika Suryawanshi, Marco Orecchioni, Jeffrey Makings, Paul J. Kim, Coleen A. McNamara, Bjoern Peters, Alessandro Sette, Klaus Ley
Publikováno v:
Circulation research, vol 131, iss 3
Background: CD (cluster of differentiation) 4 + T-cell responses to APOB (apolipoprotein B) are well characterized in atherosclerotic mice and detectable in humans. CD4 + T cells recognize antigenic peptides displayed on highly polymorphic HLA (human
Autor:
Tanyaporn Pattarabanjird, Melissa Marshall, Aditi Upadhye, Prasad Srikakulapu, James C. Garmey, Antony Haider, Angela M. Taylor, Esther Lutgens, Coleen A. McNamara
Publikováno v:
Circ Res
Circulation research, 130(7), 981-993. Lippincott Williams and Wilkins
Circulation research, 130(7), 981-993. Lippincott Williams and Wilkins
Background: B1a and B1b lymphocytes produce IgM that inactivates oxidation-specific epitopes (IgM OSE ) on LDL (low-density lipoprotein) and protects against atherosclerosis. Loss of ID3 (inhibitor of differentiation 3) in B cells selectively promote