Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Coleen, McNamara"'
Autor:
Tobias Kroon, Matthew Harms, Stefanie Maurer, Laurianne Bonnet, Ida Alexandersson, Anna Lindblom, Andrea Ahnmark, Daniel Nilsson, Peter Gennemark, Gavin O'Mahony, Victoria Osinski, Coleen McNamara, Jeremie Boucher
Publikováno v:
Molecular Metabolism, Vol 36, Iss , Pp - (2020)
Objective: Peroxisome proliferator-activated receptors (PPARs) are key transcription factors that regulate adipose development and function, and the conversion of white into brown-like adipocytes. Here we investigated whether PPARα and PPARγ activa
Externí odkaz:
https://doaj.org/article/c8f7d5b18d4a454e9d17350c34792a8f
Autor:
Sula Mazimba, Hunter Mwansa, Khadijah Breathett, Jarred E. Strickling, Kajal Shah, Coleen McNamara, Nishaki Mehta, Younghoon Kwon, Josephine Lamp, Lu Feng, Jose Tallaj, Salpy Pamboukian, Mwenya Mubanga, Jashanjeet Matharoo, Scott Lim, Michael Salerno, Victor Mwansa, Kenneth C. Bilchick
Publikováno v:
Heart and Vessels. 37:1719-1727
Ventriculo-arterial (VA) coupling has been shown to have physiologic importance in heart failure (HF). We hypothesized that the systemic arterial pulsatility index (SAPi), a measure that integrates pulse pressure and a proxy for left ventricular end-
Marginal Zone B cells produce 'natural' atheroprotective IgM antibodies in a T-cell-dependent manner
Autor:
James Harrison, Stephen Newland, Wei Jiang, Xiaohui Zhao, Marc Clement, Leanne Masters, Andrej Corovic, Xian Zhang, Fabrizio Drago, Marcella Ma, Maria Ozsvar Kozma, Froher Yasin, Yuta Saady, Hema Kothari, Tian Zhao, Guo-Ping Shi, Coleen McNamara, Christoph Binder, Andrew Sage, Jason Tarkin, Ziad Mallat, Meritxell Nus
The adaptive immune response plays an important role in atherosclerosis. In response to a high fat/high cholesterol diet, marginal zone B (MZB) cells activate an atheroprotective programme by regulating the differentiation and accumulation of T folli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4de193590e1eacce9a539c347f5b996
https://doi.org/10.21203/rs.3.rs-1753743/v1
https://doi.org/10.21203/rs.3.rs-1753743/v1
Autor:
Melissa D. Lempicki, Vlad Serbulea, Saikat Paul, Clint M. Upchurch, Srabani Sahu, Jake A. Gray, Gorav Ailawadi, Brandon L. Garcia, Coleen McNamara, Norbert Leitinger, Akshaya K. Meher
Publikováno v:
The FASEB Journal. 36
Autor:
Hema Kothari, Chantel McSkimming, Fabrizio Drago, Corey Williams, Eli Zunder, Coleen McNamara
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41
Objective: Murine data, prospective epidemiological studies, and genetic association data support a potential causal role of IL-6 signaling in atherosclerosis development. IL-6 inhibitors have emerged as potential therapeutics for reducing events in
Publikováno v:
Nature Cardiovascular Research. 1:189-190
Autor:
Prasad Srikakulapu, Tanyaporn Pattarabanjird, Sai Vineela Bontha, Aditi Upadhye, Fabrizio Drago, Melissa Marshall, Coleen McNamara
Publikováno v:
The Journal of Immunology. 208:48.09-48.09
Age-Associated B cells (ABCs: CD19+CD11c+) have recently been reported as a new subset of B cells with unique cell surface and transcriptional signatures. ABCs are mostly comprised of antigen experienced memory B cells that arise in response to micro
Publikováno v:
JACC: Basic to Translational Science
Highlights • B cells regulate atherosclerotic plaque formation through production of antibodies and cytokines, and effects are subset specific (B1 and B2). • Putative human atheroprotective B1 cells function similarly to murine B1 in their sponta
Autor:
Jeffrey Wilson, Fabrizio Drago, Lisa Workman, Angela Taylor, Thomas Platts-Mills, Coleen McNamara
Publikováno v:
Journal of Allergy and Clinical Immunology. 149:AB207
Autor:
Stefanie Kohlgrüber, Nadine Dyballa-Rukes, Sabine Metzger, Anh Nguyen, Jim Garmey, Coleen McNamara, Judith Haendeler, Joachim Altschmied
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
The transcription factor Grainyhead-like 3 (GRHL3) regulates apoptosis, migration and NO-bioavailability and thus, critical functions of endothelial cell, which are impaired in many cardiovascular diseases. However, due to the lack of a good antibody