Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Cole Urnes"'
2
Intracranial solitary fibrous tumor with delayed symptomatic metastasis to the lumbar spine: illustrative case
Autor: Simon A. Menaker, Vladimir A. Ljubimov, Viktoria O. Krutikova, Cole Urnes, Serguei I. Bannykh, Lindsey B. Ross, Paula Eboli
Publikováno v: Journal of Neurosurgery: Case Lessons. 5
BACKGROUND Intracranial solitary fibrous tumors (SFTs), formerly known as hemangiopericytomas, are rare, aggressive mesenchymal extra-axial tumors typically treated via resection, often with preoperative embolization and postoperative radiation and/o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99c7693ee71523a8d87e1ea32f349267
https://doi.org/10.3171/case22495
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3
Site-Specific Bioconjugation through Enzyme-Catalyzed Tyrosine–Cysteine Bond Formation
Autor: Matthew B. Francis, Alan M. Marmelstein, Brett T. Staahl, Johnathan C. Maza, Stephanie A. Robinson, Elijah N Kissman, Marco J. Lobba, Casey S. Mogilevsky, Rachel J. Lew, Jennifer A. Doudna, Christof Fellmann, Cole Urnes
Publikováno v: ACS Central Science, Vol 6, Iss 9, Pp 1564-1571 (2020)
ACS Central Science
The synthesis of protein–protein and protein–peptide conjugates is an important capability for producing vaccines, immunotherapeutics, and targeted delivery agents. Herein we show that the enzyme tyrosinase is capable of oxidizing exposed tyrosin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4600a77b0411205dee1e9f3902acd10d
https://doaj.org/article/717bb74132f54986ad0e5c0d11e24c37
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6
Site-Specific Generation of Protein-Protein Conjugates Using Native Amino Acids
Autor: Marco J. Lobba, Stephanie A. Robinson, Elijah N Kissman, Casey S. Mogilevsky, Brett T. Staahl, Johnathan C. Maza, Christof Fellmann, Cole Urnes, Rachel J. Lew, Matthew B. Francis, Jennifer A. Doudna, Alan M. Marmelstein
Chimeric protein-protein conjugates provide platforms for immunotherapy, targeted drug delivery, and vaccine development. However, many desirable constructs cannot be produced through direct expression, and the targeted coupling of two proteins is ch
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b179ca12313dbe33d5439dde5220813
https://doi.org/10.26434/chemrxiv.9941948.v2
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7
Site-Specific Generation of Protein-Protein Conjugates Using Native Amino Acids
Autor: Marco Lobba, Christof Fellmann, Alan Marmelstein, Johnathan Maza, Elijah Kissman, Stephanie A. Robinson, Brett T. Staahl, Cole Urnes, Rachel J. Lew, Jennifer A. Doudna, Matthew Francis
Chimeric protein-protein conjugates provide platforms for immunotherapy, targeted drug delivery, and vaccine development. However, many desirable constructs cannot be produced through direct expression, and the targeted coupling of two proteins is ch
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc4a744ea185f3fd9fa7d8754ad2dcde
https://doi.org/10.26434/chemrxiv.9941948.v1
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8
Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes
Autor: Stephen N. Floor, Anirvan Ghosh, Claire Coulon-Bainier, Ashwin A Banfal, Brett T. Staahl, Jennifer K Sabo, Gabriela Acevedo Munares, Madhurima Benekareddy, Cole Urnes, Jennifer A. Doudna
Publikováno v: Nature biotechnology, vol 35, iss 5
We demonstrate editing of post-mitotic neurons in the adult mouse brain following injection of Cas9 ribonucleoprotein (RNP) complexes in the hippocampus, striatum and cortex. Engineered variants of Cas9 with multiple SV40 nuclear localization sequenc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73798444fe303353512c41f0ca325c45
https://escholarship.org/uc/item/4ws3879m
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