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pro vyhledávání: '"Cole S. Purdy"'
Autor:
Cole S. Purdy, Amber L. Alhadeff, Denise M. DeFelice, Karthikeyani Chellappa, Yajing Peng, Sarmistha Mukherjee, Jay L. Tomasiewicz, Matthew H. Wakai, Emma Meyer, Dudley W. Lamming, Mohammed I. Alotaibi, Georgios K. Paschos, J. Nicholas Betley, Isaac J. Perron, Amy Lin, Rebecca Yao, Luigi Puglielli, Joseph A. Baur, Sebastian I. Arriola Apelo, Jacqueline A. Brinkman, Mark Morrison, Kathryn A. Carbajal
Publikováno v:
Aging Cell
The mechanistic target of rapamycin (mTOR) is an evolutionarily conserved protein kinase that regulates growth and metabolism. mTOR is found in two protein complexes, mTORC1 and mTORC2, that have distinct components and substrates and are both inhibi