Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Cole S. Nelson"'
Autor:
Julia M. Mulvaney, Cole S. Nelson, George D. Olsen, Michael Wallisch, Sue Ann Smith, Heather S. Hernandez
Publikováno v:
Biochemical Pharmacology. 73:1818-1828
Chronic opioid treatment leads to agonist-specific effects at the mu opioid receptor. The molecular mechanisms resulting from chronic opioid exposure include desensitization, internalization and down-regulation of membrane-bound mu opioid receptors (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3724bf5a68cc5fade9be55c127c9c011
https://doi.org/10.1016/j.bcp.2007.02.001
https://doi.org/10.1016/j.bcp.2007.02.001
Publikováno v:
Pediatric Pulmonology. 42:1134-1143
Respiratory depression, the most serious side-effect of opioid treatment, is well documented for morphine, the most commonly used opioid in neonatal care. Less is known about methadone, a clinically relevant opioid analgesic, especially during neonat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9832f5764e0a26323377c5ed329ad734
https://doi.org/10.1002/ppul.20707
https://doi.org/10.1002/ppul.20707
Autor:
Kim A. Neve, Charles N. Allen, Cole S. Nelson, Heinrich S. Gompf, Mindi L. Robinson, Masayuki Ikeda, Tohru Yoshioka, Nadine K. Fuchs
Publikováno v:
Molecular Endocrinology. 15:1306-1317
Melatonin is a pineal hormone that regulates seasonal reproduction and has been used to treat circadian rhythm disorders. The melatonin 1a receptor is a seven- transmembrane domain receptor that signals predominately via pertussis toxin-sensitive G-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6416761cdd68b2906aec88e271bc7b9
https://doi.org/10.1210/mend.15.8.0681
https://doi.org/10.1210/mend.15.8.0681
Autor:
David K. Grandy, Tristan Darland, Charles N. Allen, Michael A. Rea, Cole S. Nelson, Denise I. Quigley, Tohru Yoshioka, Richard G. Allen, Zhi Gen Jiang, Masayuki Ikeda, Koji Teshima
Publikováno v:
The Journal of Neuroscience. 19:2152-2160
Neurons in the suprachiasmatic nucleus (SCN) constitute the principal circadian pacemaker of mammals.In situhybridization studies revealed expression of orphanin-FQ/nociceptin (OFQ/N) receptor (NOR) mRNA in the SCN, whereas no expression of mRNA for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e241ce697c9191e896ac174b6a6c9948
https://doi.org/10.1523/jneurosci.19-06-02152.1999
https://doi.org/10.1523/jneurosci.19-06-02152.1999
Publikováno v:
Journal of Pineal Research. 26:113-121
We have used the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel as a model system to study the cAMP signal transduction pathways coupled to the Xenopus melatonin receptor. During forskolin (Fsk) stimulation, melatonin reduced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f3f5c522a1557ac9bc258a891a9ab1c
https://doi.org/10.1111/j.1600-079x.1999.tb00571.x
https://doi.org/10.1111/j.1600-079x.1999.tb00571.x
Publikováno v:
Brain Research. 687:125-132
Whole-cell voltage-clamp recordings were made from suprachiasmatic nucleus (SCN) neurons maintained in horizontal brain slices. The majority of neurons exhibited spontaneous and evoked excitatory and inhibitory synaptic currents (EPSC and IPSC), medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea5867a7d11dcb2891de515c9a0b668
https://doi.org/10.1016/0006-8993(95)00478-9
https://doi.org/10.1016/0006-8993(95)00478-9
Publikováno v:
Pediatric Pulmonology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54697390f309aecdd37eaf29c08b8f67
https://doi.org/10.1002/ppul.21250
https://doi.org/10.1002/ppul.21250
Publikováno v:
The Journal of allergy and clinical immunology. 119(6)
Background Eosinophils cluster along airway nerves in patients with asthma and release eosinophil major basic protein, an antagonist of inhibitory M2 muscarinic receptors on nerves. Blocking M2 function increases bronchoconstriction, leading to airwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fcb626760c490c0df2cbd8502a1d480
https://pubmed.ncbi.nlm.nih.gov/17418379
https://pubmed.ncbi.nlm.nih.gov/17418379
Autor:
Charles N. Allen, Tohru Yoshioka, Takashi Sugiyama, T. Shinoe, David K. Grandy, Cole S. Nelson, Masayuki Ikeda, H. Shinagawa
Publikováno v:
Cell calcium. 29(1)
We analyzed intracellular Ca(2+)and cAMP levels in Chinese hamster ovary cells expressing a cloned rat kappa opioid receptor (CHO-kappa cells). Although expression of kappa(kappa)-opioid receptors was confirmed with a fluorescent dynorphin analog in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12afdbc8e5862b96f7b8d1ff4d43744e
https://pubmed.ncbi.nlm.nih.gov/11133354
https://pubmed.ncbi.nlm.nih.gov/11133354
Autor:
Koji Teshima, Masayuki Ikeda, Zhi Gen Jiang, Cole S. Nelson, Charles N. Allen, Tohru Yoshioka
Publikováno v:
Slow Synaptic Responses and Modulation ISBN: 9784431669753
Circadian rhythms are daily patterns of physiological processes which persist in the absence of environmental time cues, indicating the existence of an endogenous biological clock. In humans, the circadian clock plays a important role in sleep-wake c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18d6dfeb6473e63bab3e3214923b9b15
https://doi.org/10.1007/978-4-431-66973-9_52
https://doi.org/10.1007/978-4-431-66973-9_52
