Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Cole Emanuelson"'
Autor:
Taylor D. Canady, April S. Berlyoung, Joe A. Martinez, Cole Emanuelson, Cheryl A. Telmer, Marcel P. Bruchez, Bruce A. Armitage
Publikováno v:
Molecules, Vol 25, Iss 4, p 970 (2020)
High affinity nucleic acid analogues such as gammaPNA (γPNA) are capable of invading stable secondary and tertiary structures in DNA and RNA targets but are susceptible to off-target binding to mismatch-containing sequences. We introduced a hairpin
Externí odkaz:
https://doaj.org/article/f4b0b4c3a2014c818ac09ecf3f3f9cec
Autor:
Cole Emanuelson, Nicholas Ankenbruck, Rohan Kumbhare, Meryl Thomas, Colleen Connelly, Yasmine Baktash, Glenn Randall, Alexander Deiters
Publikováno v:
Journal of Medicinal Chemistry. 65:16338-16352
MicroRNAs (miRNAs) are noncoding RNA molecules of 22-24 nucleotides that are estimated to regulate thousands of genes in humans, and their dysregulation has been implicated in many diseases. MicroRNA-122 (miR-122) is the most abundant miRNA in the li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8976dbcc6abe30b3b9eb3f8afc1f46f8
https://doi.org/10.1021/acs.jmedchem.2c01141
https://doi.org/10.1021/acs.jmedchem.2c01141
Publikováno v:
ACS synthetic biology. 10(7)
DNA-based Boolean logic gates (for example, AND, OR, and NOT) can be assembled into complex computational circuits that generate an output signal in response to specific patterns of oligonucleotide inputs. However, the fundamental nature of NOT gates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c866196c448432646e0eff78688ae4a
https://pubmed.ncbi.nlm.nih.gov/34142811
https://pubmed.ncbi.nlm.nih.gov/34142811
Publikováno v:
SLAS Discov
High-throughput matrix-assisted laser desorption/ionization mass spectrometry (HT-MALDI-MS) has garnered considerable attention within the drug discovery industry as an information-rich alternative to assays using light-based detection methods. To da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09f3d911c3cba06cda26c8d98b2326c6
https://pubmed.ncbi.nlm.nih.gov/32988284
https://pubmed.ncbi.nlm.nih.gov/32988284
DNA-based Boolean logic gates (AND, OR and NOT) can be assembled into complex computational circuits that generate an output signal in response to specific patterns of oligonucleotide inputs. However, the fundamental nature of NOT gates, which conver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5928a45c2f9aa99b3becbcd9a452ef41
https://doi.org/10.1101/2020.07.13.201293
https://doi.org/10.1101/2020.07.13.201293
Autor:
Meryl Thomas, Cole Emanuelson, Laura Gardner, Yuta Naro, Rohan Kumbhare, Nicholas Ankenbruck, Alexander Deiters
Publikováno v:
Bioorganicmedicinal chemistry. 27(16)
MicroRNAs (miRNAs) are short, non-coding RNA molecules estimated to regulate expression of a large number of protein-coding genes and are implicated in a variety of biological processes such as development, differentiation, proliferation, and cell su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38d155bb00b782003900bb32d315047
https://pubmed.ncbi.nlm.nih.gov/31262664
https://pubmed.ncbi.nlm.nih.gov/31262664