Pharmacological activation of the Sonic hedgehog pathway with a Smoothened small molecule agonist ameliorates the severity of alcohol-induced morphological and behavioral birth defects in a zebrafish model of fetal alcohol spectrum disorder.

Autor: Burton DF; Biomanufacturing Research Institute and Technology Enterprise, North Carolina Central University, Durham, North Carolina, USA., Boa-Amponsem OM; Integrated Biosciences PhD Program, North Carolina Central University, Durham, North Carolina, USA.; Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University, Durham, North Carolina, USA., Dixon MS; Biomanufacturing Research Institute and Technology Enterprise, North Carolina Central University, Durham, North Carolina, USA., Hopkins MJ; Department of Pharmaceutical Sciences, North Carolina Central University, Durham, North Carolina, USA., Herbin TA; Department of Pharmaceutical Sciences, North Carolina Central University, Durham, North Carolina, USA., Toney S; Department of Pharmaceutical Sciences, North Carolina Central University, Durham, North Carolina, USA., Tarpley M; Biomanufacturing Research Institute and Technology Enterprise, North Carolina Central University, Durham, North Carolina, USA., Rodriguez BV; Department of Biochemistry, Duke University, Durham, North Carolina, USA., Fish EW; Bowles Center for Alcohol Studies, University of North Carolina, Chapel Hill, North Carolina, USA., Parnell SE; Bowles Center for Alcohol Studies, University of North Carolina, Chapel Hill, North Carolina, USA.; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, North Carolina, USA., Cole GJ; Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University, Durham, North Carolina, USA.; Department of Biological and Biomedical Sciences, North Carolina Central University, Durham, North Carolina, USA., Williams KP; Biomanufacturing Research Institute and Technology Enterprise, North Carolina Central University, Durham, North Carolina, USA.; Department of Pharmaceutical Sciences, North Carolina Central University, Durham, North Carolina, USA.

Publikováno v: Journal of neuroscience research [J Neurosci Res] 2022 Aug; Vol. 100 (8), pp. 1585-1601. Date of Electronic Publication: 2022 Jan 11.

Factors regulating the gripping force and stiffness of 25- and 27-gauge internal limiting membrane forceps.

Autor: Katakami, Kana¹ (AUTHOR), Imai, Hisanori^1,2 (AUTHOR) imaih@hirakata.kmu.ac.jp, Sotani, Yasuyuki¹ (AUTHOR), Yamada, Hiroko¹ (AUTHOR), Nakamura, Makoto¹ (AUTHOR)

Publikováno v: PLoS ONE. 11/5/2024, Vol. 19 Issue 11, p1-12. 12p.

Cannabinoids Exacerbate Alcohol Teratogenesis by a CB1-Hedgehog Interaction.

Autor: Fish EW; Bowles Center for Alcohol Studies, University of North Carolina, Chapel Hill, NC, USA., Murdaugh LB; Bowles Center for Alcohol Studies, University of North Carolina, Chapel Hill, NC, USA., Zhang C; Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University, Durham, NC, USA., Boschen KE; Bowles Center for Alcohol Studies, University of North Carolina, Chapel Hill, NC, USA., Boa-Amponsem O; Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University, Durham, NC, USA.; Integrated Biosciences Program, North Carolina Central University, Durham, NC, USA., Mendoza-Romero HN; Bowles Center for Alcohol Studies, University of North Carolina, Chapel Hill, NC, USA., Tarpley M; Biomanufacturing Research Institute and Technology Enterprise, North Carolina Central University, Durham, NC, USA., Chdid L; Biomanufacturing Research Institute and Technology Enterprise, North Carolina Central University, Durham, NC, USA., Mukhopadhyay S; Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University, Durham, NC, USA.; Department of Chemistry and Biochemistry, North Carolina Central University, Durham, NC, USA., Cole GJ; Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University, Durham, NC, USA.; Department of Biological and Biomedical Sciences, North Carolina Central University, Durham, NC, USA., Williams KP; Biomanufacturing Research Institute and Technology Enterprise, North Carolina Central University, Durham, NC, USA.; Department of Pharmaceutical Sciences, BRITE Institute, North Carolina Central University, Durham, NC, USA., Parnell SE; Bowles Center for Alcohol Studies, University of North Carolina, Chapel Hill, NC, USA. sparnell@med.unc.edu.; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC, USA. sparnell@med.unc.edu.; Carolina Institute for Developmental Disabilities, University of North Carolina, Chapel Hill, NC, USA. sparnell@med.unc.edu.

Publikováno v: Scientific reports [Sci Rep] 2019 Nov 05; Vol. 9 (1), pp. 16057. Date of Electronic Publication: 2019 Nov 05.

Current evidence of synaptic dysfunction after stroke: Cellular and molecular mechanisms.

Autor: Li, Chuan¹ (AUTHOR), Jiang, Min² (AUTHOR), Fang, Zhi‐Ting³ (AUTHOR), Chen, Zhiying⁴ (AUTHOR), Li, Li⁵ (AUTHOR), Liu, Ziying¹ (AUTHOR), Wang, Junmin⁶ (AUTHOR), Yin, Xiaoping⁴ (AUTHOR) xiaopingbuxiao@126.com, Wang, Jian⁶ (AUTHOR) jianwang2020@outlook.com, Wu, Moxin^1,2 (AUTHOR) mxwu1986@jju.edu.cn

Publikováno v: CNS Neuroscience & Therapeutics. May2024, Vol. 30 Issue 5, p1-14. 14p.

Reduced fetal cerebral blood flow predicts perinatal mortality in a mouse model of prenatal alcohol and cannabinoid exposure.

Autor: Rouzer, Siara Kate¹ (AUTHOR), Sreeram, Anirudh¹ (AUTHOR), Miranda, Rajesh C.¹ (AUTHOR) rmiranda@tamu.edu

Publikováno v: BMC Pregnancy & Childbirth. 4/11/2024, Vol. 24 Issue 1, p1-13. 13p.