Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Colchifoline"'
Autor:
Irina P. Beletskaya, Iuliia A. Gracheva, V. I. Faerman, Elena V. Svirshchevskaya, Alexey Yu. Fedorov
Publikováno v:
Synthesis. 50:2753-2760
Based on the natural antimitotic agent colchifoline as a lead structure, a series of novel bifunctional allocolchicine congeners were synthesized from commercial colchicine. The new derivatives maintain good cytotoxicity against T3M4, MiaPaCa-2, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c1244a05103121beea04668de758584
https://doi.org/10.1055/s-0037-1610146
https://doi.org/10.1055/s-0037-1610146
Publikováno v:
Chemistry of Natural Compounds. 51:512-514
A new colchicinoid from the seeds of Colchicum umbrosum (Colchicaceae) has been isolated and identified as 4-hydroxycolchicine (6) together with seven known colchicinoids as colchicine (1), N-deacetyl-N-formylcolchicine (2), colchifoline (3), colchic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b2341c1e1c821e48d2deb53c510c112
https://doi.org/10.1007/s10600-015-1326-4
https://doi.org/10.1007/s10600-015-1326-4
Publikováno v:
Biochemical Systematics and Ecology. 31:715-722
Androcymbium gramineum plants were phytochemically investigated for alkaloids. Two major alkaloids, colchicine and demecolcine, were isolated from the whole plant, and 2-demethylcolchicine, 3-demethylcolchicine, N-formyl-N-deacetylcolchicine and colc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4340fe12b1bcd3eb4abdb70ae532eff7
https://doi.org/10.1016/s0305-1978(02)00248-x
https://doi.org/10.1016/s0305-1978(02)00248-x
Autor:
Paam N. Sharma, Arnold Brossi
Publikováno v:
Helvetica Chimica Acta. 67:301-304
Reaction of decetylcolchicine (2) and colchifoline (3) with diacetyldihydrofluorescein (1, DADF) afforded the corresponding amide and ester derivatives, converted on TLC-plates after exposure to ammonia and iodine vapors into red colored pigments. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46bfeb04749d0fbedea32ff77f831ddf
https://doi.org/10.1002/hlca.19840670136
https://doi.org/10.1002/hlca.19840670136
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Publikováno v:
Chemischer Informationsdienst. 16
Spin probes of deacetylcholchicine (1), 4-(hydroxymethyl)colchicine (2), and colchifoline (3) have been synthesized to study the binding site for colchicine on tubulin. Acylation of 1-3 with (+/-)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy-3-carboxylic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9572c773be478bc853f51e213428c211
https://doi.org/10.1002/chin.198523177
https://doi.org/10.1002/chin.198523177
Autor:
Arnold Brossi, Paam N. Sharma
Publikováno v:
Chemischer Informationsdienst. 15
Reaction of decetylcolchicine (2) and colchifoline (3) with diacetyldihydrofluorescein (1, DADF) afforded the corresponding amide and ester derivatives, converted on TLC-plates after exposure to ammonia and iodine vapors into red colored pigments. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2af08940f8dda074aac75b8dab36024
https://doi.org/10.1002/chin.198416223
https://doi.org/10.1002/chin.198416223
Publikováno v:
Chemischer Informationsdienst. 12
Treatment of a mixture of deacetylcolchicine and deacetylisocolchicine, obtained by diazomethane methylation of deacetylcolchiceine, with trifluoroacetylglycolyl chloride in pyridine, afforded directly colchifoline and isocolchifoline. The two ether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6866e8c940723514248eb00926377c03
https://doi.org/10.1002/chin.198125328
https://doi.org/10.1002/chin.198125328
Publikováno v:
Canadian Journal of Chemistry. 59:283-284
Treatment of a mixture of deacetylcolchicine and deacetylisocolchicine, obtained by diazomethane methylation of deacetylcolchiceine, with trifluoroacetylglycolyl chloride in pyridine, afforded directly colchifoline and isocolchifoline. The two ether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97be0adc4da218733a665f14866892ec
https://doi.org/10.1139/v81-045
https://doi.org/10.1139/v81-045
Autor:
Arnold Brossi
Publikováno v:
Trends in Pharmacological Sciences. 4:327-328
Partial synthesis of a variety of minor Colchicum alkaloids, including demecolcine, cornigerine, colchifoline, and phenolic congeners has been accomplished. An X-ray analysis of biologically ‘active' and ‘inactive' representatives showed that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41bce3d015e3dfcdac4c6291df82ccde
https://doi.org/10.1016/0165-6147(83)90425-x
https://doi.org/10.1016/0165-6147(83)90425-x