Development of High-Loading Trastuzumab PLGA Nanoparticles: A Powerful Tool Against HER2 Positive Breast Cancer Cells

Autor: Caputo TM, Barisciano G, Mulè C, Cusano AM, Aliberti A, Muccillo L, Colantuoni V, Sabatino L, Cusano A

Publikováno v: International Journal of Nanomedicine, Vol Volume 18, Pp 6999-7020 (2023)

Tania Mariastella Caputo,1,* Giovannina Barisciano,2,* Chiara Mulè,1 Angela Maria Cusano,3 Anna Aliberti,1 Livio Muccillo,2 Vittorio Colantuoni,2 Lina Sabatino,2 Andrea Cusano1,3 1Optoelectronics Group, Department of Engineering, University

Externí odkaz: https://doaj.org/article/359af861718841e9b155c88092b68036

Limiting serine availability during tumor progression promotes muscle wasting in cancer cachexia.

Autor: Pranzini E; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy., Muccillo L; Department of Sciences and Technologies, University of Sannio, Benevento, Italy.; AREA Science Park, Padriciano, 99, Trieste, Italy., Nesi I; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy., Santi A; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy., Mancini C; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy., Lori G; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy., Genovese M; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy., Lottini T; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Comito G; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy., Caselli A; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy., Arcangeli A; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Sabatino L; Department of Sciences and Technologies, University of Sannio, Benevento, Italy., Colantuoni V; Department of Sciences and Technologies, University of Sannio, Benevento, Italy., Taddei ML; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Cirri P; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy., Paoli P; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy. paolo.paoli@unifi.it.

Publikováno v: Cell death discovery [Cell Death Discov] 2024 Dec 21; Vol. 10 (1), pp. 510. Date of Electronic Publication: 2024 Dec 21.

Loss of circadian gene Timeless induces EMT and tumor progression in colorectal cancer via Zeb1-dependent mechanism.

Autor: Colangelo T; Fondazione IRCCS Casa Sollievo della Sofferenza, Cancer Biomarkers Unit, Viale Padre Pio 7, 71013, San Giovanni Rotondo, (FG), Italy., Carbone A; Fondazione IRCCS Casa Sollievo della Sofferenza, Department of Medical Sciences, Division of Internal Medicine and Chronobiology Laboratory, Viale Cappuccini snc, 71013, San Giovanni Rotondo, (FG), Italy., Mazzarelli F; Fondazione IRCCS Casa Sollievo della Sofferenza, Cancer Biomarkers Unit, Viale Padre Pio 7, 71013, San Giovanni Rotondo, (FG), Italy., Cuttano R; Fondazione IRCCS Casa Sollievo della Sofferenza, Cancer Biomarkers Unit, Viale Padre Pio 7, 71013, San Giovanni Rotondo, (FG), Italy., Dama E; Fondazione IRCCS Casa Sollievo della Sofferenza, Cancer Biomarkers Unit, Viale Padre Pio 7, 71013, San Giovanni Rotondo, (FG), Italy., Nittoli T; Fondazione IRCCS Casa Sollievo della Sofferenza, Cancer Biomarkers Unit, Viale Padre Pio 7, 71013, San Giovanni Rotondo, (FG), Italy., Albanesi J; Department of Sciences, Roma Tre University, Viale G. Marconi, 446, 00154, Rome, (RM), Italy., Barisciano G; Department of Sciences and Technologies, University of Sannio, Via Traiano, 3, 82100, Benevento, (BN), Italy., Forte N; UOC- Patologia Clinica-Settore Anatomia Patologica, Ospedale Fatebenefratelli, Viale Principe di Napoli, 14/A, 82100, Benevento, (BN), Italy., Palumbo O; Fondazione IRCCS Casa Sollievo della Sofferenza, Division of Medical Genetics, Viale Padre Pio, 7d, 71013, San Giovanni Rotondo, (FG), Italy., Graziano P; Pathology Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini snc, 71013, San Giovanni Rotondo, (FG), Italy., di Masi A; Department of Sciences, Roma Tre University, Viale G. Marconi, 446, 00154, Rome, (RM), Italy., Colantuoni V; Department of Sciences and Technologies, University of Sannio, Via Traiano, 3, 82100, Benevento, (BN), Italy., Sabatino L; Department of Sciences and Technologies, University of Sannio, Via Traiano, 3, 82100, Benevento, (BN), Italy., Bianchi F; Fondazione IRCCS Casa Sollievo della Sofferenza, Cancer Biomarkers Unit, Viale Padre Pio 7, 71013, San Giovanni Rotondo, (FG), Italy. f.bianchi@operapadrepio.it., Mazzoccoli G; Fondazione IRCCS Casa Sollievo della Sofferenza, Department of Medical Sciences, Division of Internal Medicine and Chronobiology Laboratory, Viale Cappuccini snc, 71013, San Giovanni Rotondo, (FG), Italy. g.mazzoccoli@operapadrepio.it.

Publikováno v: Cell death and differentiation [Cell Death Differ] 2022 Aug; Vol. 29 (8), pp. 1552-1568. Date of Electronic Publication: 2022 Jan 15.

Correction: miR-27a is a master regulator of metabolic reprogramming and chemoresistance in colorectal cancer (British Journal of Cancer, (2020), 122, 9, (1354-1366), 10.1038/s41416-020-0773-2)

Autor: Barisciano G., Colangelo T., Rosato V., Muccillo L., Taddei M. L., Ippolito L., Chiarugi P., Galgani M., Bruzzaniti S., Matarese G., Fassan M., Agostini M., Bergamo F., Pucciarelli S., Carbone A., Mazzoccoli G., Colantuoni V., Bianchi F., Sabatino L.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3730::ce2b9f45230f00b3fe0cdc4f734b02a4
http://hdl.handle.net/11588/872105

SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis.

Autor: Pranzini E; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy. Electronic address: erica.pranzini@unifi.it., Pardella E; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy., Muccillo L; Department of Sciences and Technologies, University of Sannio, Via Francesco de Sanctis, 82100 Benevento, Italy., Leo A; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy., Nesi I; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy., Santi A; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy., Parri M; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy., Zhang T; Institute of Cancer Sciences, Wolfson Wohl Cancer Research Centre, University of Glasgow, Switchback Road, Glasgow G61 1QH, UK; Novartis Institutes for BioMedical Research, Shanghai, China., Uribe AH; Institute of Cancer Sciences, Wolfson Wohl Cancer Research Centre, University of Glasgow, Switchback Road, Glasgow G61 1QH, UK., Lottini T; Department of Experimental and Clinical Medicine, University of Florence, Viale Morgagni 50, 50134 Florence, Italy., Sabatino L; Department of Sciences and Technologies, University of Sannio, Via Francesco de Sanctis, 82100 Benevento, Italy., Caselli A; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy., Arcangeli A; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy., Raugei G; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy., Colantuoni V; Department of Sciences and Technologies, University of Sannio, Via Francesco de Sanctis, 82100 Benevento, Italy., Cirri P; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy., Chiarugi P; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy., Maddocks ODK; Institute of Cancer Sciences, Wolfson Wohl Cancer Research Centre, University of Glasgow, Switchback Road, Glasgow G61 1QH, UK., Paoli P; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy. Electronic address: paolo.paoli@unifi.it., Taddei ML; Department of Experimental and Clinical Medicine, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.

Publikováno v: Cell reports [Cell Rep] 2022 Aug 16; Vol. 40 (7), pp. 111233.