Zobrazeno 1 - 10
of 636
pro vyhledávání: '"Col1a2"'
Autor:
Yulia S. Koshevaya, Mariia E. Turkunova, Anastasia O. Vechkasova, Elena A. Serebryakova, Maxim Yu. Donnikov, Svyatoslav I. Papanov, Alexander N. Chernov, Lev N. Kolbasin, Lyudmila V. Kovalenko, Andrey S. Glotov, Oleg S. Glotov
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 5, Pp 4106-4118 (2024)
Osteogenesis imperfecta (OI) is a group of inherited disorders of connective tissue that cause significant deformities and fragility in bones. Most cases of OI are associated with pathogenic variants in collagen type I genes and are characterized by
Externí odkaz:
https://doaj.org/article/c9c348e41fe94a8ca1e5079e95152198
Autor:
Jun Xu, Kaifeng Zhou, Huijie Gu, Yiming Zhang, Liang Wu, Chong Bian, Zhongyue Huang, Guangnan Chen, Xiangyang Cheng, Xiaofan Yin
Publikováno v:
Biomolecules & Biomedicine (2023)
This study aimed to elucidate the roles of microRNA (miR)-4738-3p and the collagen type I alpha 2 chain (COL1A2) gene in the pathogenesis of osteoarthritis (OA) through bioinformatics analysis and cellular assays. The GSE55235 dataset was analyzed us
Externí odkaz:
https://doaj.org/article/87ec81c157284939990cc69a9bddd9dc
Autor:
Kinga Sałacińska, Iwona Pinkier, Lena Rutkowska, Danuta Chlebna-Sokół, Elżbieta Jakubowska-Pietkiewicz, Izabela Michałus, Łukasz Kępczyński, Dominik Salachna, Nina Wieczorek-Cichecka, Małgorzata Piotrowicz, Tatiana Chilarska, Aleksander Jamsheer, Paweł Matusik, Małgorzata Wilk, Elżbieta Petriczko, Maria Giżewska, Iwona Stecewicz, Mieczysław Walczak, Magda Rybak-Krzyszkowska, Andrzej Lewiński, Agnieszka Gach
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Osteogenesis imperfecta (OI) is a rare genetic disorder of the connective tissue. It presents with a wide spectrum of skeletal and extraskeletal features, and ranges in severity from mild to perinatal lethal. The disease is characterized by a heterog
Externí odkaz:
https://doaj.org/article/f46f73cf625d46ddb2885a7702d86c5c
Publikováno v:
International Journal of Medical Biochemistry, Vol 5, Iss 3, Pp 137-151 (2022)
INTRODUCTION: The scope of this study was to identify potential genes as a promising biomarker in diagnosing cholangiocarcinoma (CCA) or differentiating the subtypes of CCA. In this study, we used Gene Expression Omnibus (GEO)-NCBI data sets as promi
Externí odkaz:
https://doaj.org/article/53a91c4ff9cb487b8e35f416112de0ee
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-8 (2022)
Abstract Background Osteogenesis imperfecta (OI) is the most common monogenic disease of the skeletal system and is usually caused by mutations in the COL1A1 or COL1A2 genes. Congenital contractural arachnodactyly syndrome (CCA) is an autosomal domin
Externí odkaz:
https://doaj.org/article/204eeba8a5984a32b287603584d62ae8
Publikováno v:
Neuropsychiatric Disease and Treatment, Vol Volume 17, Pp 3301-3314 (2021)
Lina Feng,1 Mingquan Li,2 Jixiang Ren,3 Yujuan Li,4 Qi Wang,5 Pengqi Zhang,1 Xinyue Zhang,1 Tianye Wang,5 Yunqiang Li1 1College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, Jilin Province, People’s Republic
Externí odkaz:
https://doaj.org/article/7b7f1ca2aa2442a3828f34d8cce4ccc1
Autor:
Carmen del Río, Francisco Ruiz-Pino, María E. Prados, Bernd L. Fiebich, Manuel Tena-Sempere, Eduardo Muñoz
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cannabidiol (CBD) has been suggested as a potential therapy for inflammatory and fibrotic diseases. Cannabidiol was demonstrated to reduce alcohol-induced liver inflammation and steatosis but its specific activity on the fibrotic process was not inve
Externí odkaz:
https://doaj.org/article/d9f6b50fa7d8420bb1c26291765cf6ba
Akademický článek
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Autor:
Katie J. Lee, Lisa Rambault, George Bou-Gharios, Peter D. Clegg, Riaz Akhtar, Gabriela Czanner, Rob van ‘t Hof, Elizabeth G. Canty-Laird
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 9 (2022)
Externí odkaz:
https://doaj.org/article/85128b1290fb417e9c2ede93c46f1d2d
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
Congenital talipes equinovarus (CTEV) is one of the most common congenital limb defects in children, which is a multifactorial and complex disease that associates with many unknown genetic, social-demographic, and environmental risk factors. Emerging
Externí odkaz:
https://doaj.org/article/ff53c458e49c422ebbd90bd2e3a97038