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Autor:
Burcu Ayhan-Sahin, Zeynep-Elif Apaydın, Pınar Obakan-Yerlikaya, Elif-Damla Arisan, Ajda Coker-Gurkan
Publikováno v:
PLoS ONE, Vol 17, Iss 1 (2022)
Background Growth Hormone Releasing Hormone (GHRH), 44 amino acids containing hypothalamic hormone, retains the biological activity by its first 29 amino acids. GHRH (NH2 1–29) peptide antagonists inhibit the growth of prostate, breast, ovarian, re
Externí odkaz:
https://doaj.org/article/6865848e6053426baa676874ec0c347b
Autor:
Arisan, Elif D., Akar, Remzi O., Rencuzogullari, Ozge, Obakan Yerlikaya, Pinar, Coker Gurkan, Ajda, Akın, Beyza, Dener, Elif, Kayhan, Ecem, Palavan Unsal, Narcin
Publikováno v:
In Prostate International December 2019 7(4):156-165
Autor:
Elif D. Arisan, Remzi O. Akar, Ozge Rencuzogullari, Pinar Obakan Yerlikaya, Ajda Coker Gurkan, Beyza Akın, Elif Dener, Ecem Kayhan, Narcin Palavan Unsal
Publikováno v:
Prostate International, Vol 7, Iss 4, Pp 156-165 (2019)
Background: Prostate cancer is the most common type of cancer among men. Studies showed that the regular use of nonsteroidal antiinflammatory drugs might reduce disease progression risk for prostate cancer patients with prostate cancer. We evaluated
Externí odkaz:
https://doaj.org/article/69b11a73a236464684958cf4882dac89
Autor:
Pelin Ozfiliz Kilbas, Ozlem Sonmez, Pinar Uysal-Onganer, Ajda Coker Gurkan, Pinar Obakan Yerlikaya, Elif Damla Arisan
Publikováno v:
Biology, Vol 9, Iss 10, p 320 (2020)
Paclitaxel (PTX) is a widely used chemotherapeutic agent in the treatment of breast cancer, and resistance to PTX is a common failure of breast cancer therapy. Therefore, understanding the effective molecular targets in PTX-resistance gains importanc
Externí odkaz:
https://doaj.org/article/f3225cddd9c344dba62d81f5a3acc80a
Autor:
Sina Kashani, Pelin Ozfiliz Kilbas, Pinar Obakan Yerlikaya, Ajda Coker Gurkan, Elif Damla Arisan
Publikováno v:
Proceedings, Vol 40, Iss 1, p 42 (2020)
Prostate cancer is the second common cause of death among men worldwide. In the treatment of prostate cancer, conventional chemotherapeutics are commonly used. The plant alkaloid Paclitaxel and platinum-based cisplatin are the most common chemotherap
Externí odkaz:
https://doaj.org/article/87f271a934194af797af9f077e0eec40
Publikováno v:
Amino Acids. 54:71-84
Autocrine growth hormone (GH) expression triggers cell proliferation, invasion-metastasis in vitro and in vivo models, but GH gene mutations inhibit postnatal growth. Natural polyamines (PA); putrescine, spermidine, spermine trigger cell growth and d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e1a3808879e3f05a6fdf8642b43fccd
https://doi.org/10.1007/s00726-021-03101-9
https://doi.org/10.1007/s00726-021-03101-9
Autor:
Ajda Coker-Gurkan, Burcu Ayhan-Sahin
Publikováno v:
International Journal of Cancer Science and Therapy. :1-10
Background: Cycline-dependent kinase inhibitors (CDKi); roscovitine and purvalanol, are promising anti-cancer drugs due to their strong anti-proliferative effectiveness due to activation of PA catabolism. Besides transforming acetylated spermine and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db06941cec9662c9a3a1292fea9bf668
https://doi.org/10.31487/j.ijcst.2021.01.03
https://doi.org/10.31487/j.ijcst.2021.01.03
Publikováno v:
Proceedings, Vol 40, Iss 1, p 9 (2019)
Breast cancer is the most common cancer in women worldwide and the second most common cancer overall. Autocrine growth hormone (GH) expression induced cell proliferation, growth, invasion-metastasis in vitro and in vivo breast cancer models. Moreover
Externí odkaz:
https://doaj.org/article/cd562e893fd347869b713fbbaa81eda2