Identification of a cancer stem cell-specific function for the histone deacetylases, HDAC1 and HDAC7, in breast and ovarian cancer.

Autor: Witt AE; Department of Pathology, Interdisciplinary Stem Cell Institute, Braman Family Breast Cancer Institute, Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, USA., Lee CW; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Lee TI; The Whitehead Institute for Biomedical Research, Cambridge, MA, USA., Azzam DJ; Department of Psychiatry and Behavioral Sciences, Center for Therapeutic Innovation, University of Miami Miller School of Medicine, Miami, FL, USA., Wang B; Department of Pathology, Interdisciplinary Stem Cell Institute, Braman Family Breast Cancer Institute, Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, USA., Caslini C; Department of Pathology, Interdisciplinary Stem Cell Institute, Braman Family Breast Cancer Institute, Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, USA., Petrocca F; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Grosso J; Department of Pathology, Interdisciplinary Stem Cell Institute, Braman Family Breast Cancer Institute, Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, USA., Jones M; Department of Pathology, Interdisciplinary Stem Cell Institute, Braman Family Breast Cancer Institute, Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, USA., Cohick EB; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; The Whitehead Institute for Biomedical Research, Cambridge, MA, USA., Gropper AB; The Whitehead Institute for Biomedical Research, Cambridge, MA, USA., Wahlestedt C; Department of Psychiatry and Behavioral Sciences, Center for Therapeutic Innovation, University of Miami Miller School of Medicine, Miami, FL, USA., Richardson AL; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Shiekhattar R; Department of Human Genetics, University of Miami Miller School of Medicine, Sylvester Comprehensive Cancer Center, Biomedical Research Building, Miami, Florida, USA., Young RA; The Whitehead Institute for Biomedical Research, Cambridge, MA, USA., Ince TA; Department of Pathology, Interdisciplinary Stem Cell Institute, Braman Family Breast Cancer Institute, Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, USA.

Publikováno v: Oncogene [Oncogene] 2017 Mar 23; Vol. 36 (12), pp. 1707-1720. Date of Electronic Publication: 2016 Oct 03.