Experiences in the design and implementation of phase II trials in CLL

Autor: Cohen Dena R, Hillmen Peter, Brown Julia M, Gregory Walter M

Publikováno v: Trials, Vol 12, Iss Suppl 1, p A92 (2011)

Externí odkaz: https://doaj.org/article/5c62b9bd4e594f568a8509fb8a0252f3

Long-term treatment with eculizumab in paroxysmal nocturnal hemoglobinuria: sustained efficacy and improved survival

Autor: Kelly, Richard J., Hill, Anita, Arnold, Louise M., Brooksbank, Gemma L., Richards, Stephen J., Cullen, Matthew, Mitchell, Lindsay D., Cohen, Dena R., Gregory, Walter M., Hillmen, Peter

Publikováno v: In Blood 23 June 2011 117(25):6786-6792

A randomized phase II trial of fludarabine, cyclophosphamide and mitoxantrone (FCM) with or without rituximab in previously treated chronic lymphocytic leukaemia

Autor: Hillmen, Peter, Cohen, Dena R., Cocks, Kim, Pettitt, Andrew, Sayala, Hazem A., Rawstron, Andy C., Kennedy, Daniel B., Fegan, Christopher, Milligan, Don W., Radford, John, Mercieca, Jane, Dearden, Claire, Ezekwisili, Raphael, Smith, Alexandra F., Brown, Julia, Booth, Gillian A., Varghese, Abraham M., Pocock, Christopher

Publikováno v: Hillmen, P, Cohen, D R, Cocks, K, Pettitt, A, Sayala, H A, Rawstron, A C, Kennedy, D B, Fegan, C, Milligan, D W, Radford, J, Mercieca, J, Dearden, C, Ezekwisili, R, Smith, A F, Brown, J, Booth, G A, Varghese, A M & Pocock, C 2011, ' A randomized phase II trial of fludarabine, cyclophosphamide and mitoxantrone (FCM) with or without rituximab in previously treated chronic lymphocytic leukaemia ', British Journal of Haematology, vol. 152, no. 5, pp. 570-578 . https://doi.org/10.1111/j.1365-2141.2010.08317.x

Combination fludarabine (F), cyclophosphamide (C) and rituximab (R) is the standard front-line therapy in chronic lymphocytic leukaemia (CLL), but appropriate treatment of relapsed/refractory CLL is less clear. Combined FC and mitoxantrone (M) has be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3818::12fb955e3901642c18668251c51b0766
https://doi.org/10.1111/j.1365-2141.2010.08317.x

Long Term Treatment with Eculizumab In Paroxysmal Nocturnal Hemoglobinuria (PNH): Sustained Efficacy and Improved Survival

Autor: Kelly, Richard J ^*, Hill, Anita ^*, Mitchell, Lindsay D ^*, Richards, Stephen John, Arnold, Louise M ^*, Valters, Gemma L ^*, Cullen, Matthew ^*, Cohen, Dena R ^*, Gregory, Walter M ^*, Hillmen, Peter

Publikováno v: In Blood 19 November 2010 116(21):639-639