Analysis and Prediction of Structural Motifs in the Glycolytic Enzymes [and Discussion]

Autor: Sternberg, M. J. E., Cohen, F. E., Taylor, W. R., Feldmann, R. J., Smit, J. D. G.

Publikováno v: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 1981 Jun . 293(1063), 177-189.

Externí odkaz: https://www.jstor.org/stable/2395668

1. Interferon: A Tertiary Structure Predicted from Amino Acid Sequences

Autor: Sternberg, M. J. E., Cohen, F. E.

Publikováno v: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 1982 Sep . 299(1094), 125-127.

Externí odkaz: https://www.jstor.org/stable/2395892

Erratum: Strain-specified characteristics of mouse synthetic prions (Proceedings of the National Academy of Sciences of the United States of America (February 8, 2005) 102, 6 (2168-2173) DOI: 10.1073/pnas.0409079102)

Autor: Legname, G., Nguyen, H. -O. B., Baskakov, I. V., Cohen, F. E., Dearmond, S. J., Prusiner, S. B.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______288::52bc15723eff95cc278b5ca45bcf7bda
http://hdl.handle.net/20.500.11767/15603

Apolipoprotein (apo) E4 enhances amyloid beta peptide production in cultured neuronal cells: ApoE structure as a potential therapeutic target

Autor: Ye, S M, Huang, Y D, Mullendorff, K, Dong, L M, Giedt, G, Meng, E C, Cohen, F E, Kuntz, I D, Weisgraber, Karl H, Mahley, R W

Publikováno v: Ye, S M; Huang, Y D; Mullendorff, K; Dong, L M; Giedt, G; Meng, E C; et al.(2005). Apolipoprotein (apo) E4 enhances amyloid beta peptide production in cultured neuronal cells: ApoE structure as a potential therapeutic target. Proceedings of the National Academy of Sciences of the United States of America, 102(51), 18700-18705. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/2tq6k7v4

Apolipoprotein (apo) E4 is a major risk factor for Alzheimer's disease, and many studies have suggested that apoE has isoform-specific effects on the deposition or clearance of amyloid beta (A beta) peptides. We examined the effects of apoE isoforms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::331d595a6a0334f411e08b5d6f40559b
http://www.escholarship.org/uc/item/2tq6k7v4

Evidence for assembly of prions with left-handed beta-helices into trimers

Autor: Govaerts, C, Wille, H, Prusiner, S B, Cohen, F E

Publikováno v: Govaerts, C; Wille, H; Prusiner, S B; & Cohen, F E. (2004). Evidence for assembly of prions with left-handed beta-helices into trimers. Proceedings of the National Academy of Sciences of the United States of America, 101(22), 8342-8347. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/56h2p2xf

Studies using low-resolution fiber diffraction, electron microscopy, and atomic force microscopy on various amyloid fibrils indicate that the misfolded conformers must be modular, compact, and adopt a cross-beta structure. In an earlier study, we use

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::0d032faa4defcecd43195c632f6b4903
http://www.escholarship.org/uc/item/56h2p2xf