Towards the design of ligands of the internal pocket TEADs C-terminal domain.

Autor: Toulotte F; Univ Lille, INSERM, CHU Lille, UMR-S 1172, Lille Neuroscience and Cognition Research Center, F-59000, Lille, France., Coevoet M; Univ Lille, INSERM, CHU Lille, UMR-S 1172, Lille Neuroscience and Cognition Research Center, F-59000, Lille, France., Liberelle M; Univ Lille, INSERM, CHU Lille, UMR-S 1172, Lille Neuroscience and Cognition Research Center, F-59000, Lille, France., Bailly F; Univ Lille, INSERM, CHU Lille, UMR-S 1172, Lille Neuroscience and Cognition Research Center, F-59000, Lille, France., Zagiel B; Univ Lille, INSERM, CHU Lille, UMR-S 1172, Lille Neuroscience and Cognition Research Center, F-59000, Lille, France., Gelin M; Centre de Biologie Structurale (CBS), CNRS, INSERM, Univ Montpellier, F-34090, Montpellier, France., Allemand F; Centre de Biologie Structurale (CBS), CNRS, INSERM, Univ Montpellier, F-34090, Montpellier, France., Fourquet P; Centre de Recherche en Cancérologie de Marseille (CRCM), CNRS, INSERM, Marseille Protéomique, Institut Paoli-Calmettes, Aix Marseille University, 27 Bvd Leï Roure, CS 30059, 13273 Marseille, France., Melnyk P; Univ Lille, INSERM, CHU Lille, UMR-S 1172, Lille Neuroscience and Cognition Research Center, F-59000, Lille, France. Electronic address: patricia.melnyk@univ-lille.fr., Guichou JF; Centre de Biologie Structurale (CBS), CNRS, INSERM, Univ Montpellier, F-34090, Montpellier, France. Electronic address: guichou@cbs.cnrs.fr., Cotelle P; Univ Lille, INSERM, CHU Lille, UMR-S 1172, Lille Neuroscience and Cognition Research Center, F-59000, Lille, France; ENSCL-Centrale Lille, CS 90108, F-59652, Villeneuve d'Ascq, France.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2025 Jan 15; Vol. 282, pp. 117026. Date of Electronic Publication: 2024 Nov 12.

High ligand efficiency quinazoline compounds as novel A 2A adenosine receptor antagonists.

Autor: Bolteau R; Univ. Lille, Inserm, CHU Lille, U1172, LilNCog - Lille Neuroscience & Cognition, F-59000, Lille, France., Duroux R; Univ. Lille, Inserm, CHU Lille, U1172, LilNCog - Lille Neuroscience & Cognition, F-59000, Lille, France., Laversin A; Univ. Lille, Inserm, CHU Lille, U1172, LilNCog - Lille Neuroscience & Cognition, F-59000, Lille, France., Vreulz B; Univ. Lille, Inserm, CHU Lille, U1172, LilNCog - Lille Neuroscience & Cognition, F-59000, Lille, France., Shiriaeva A; Department of Chemistry, University of Southern California, Los Angeles, CA, USA., Stauch B; Bridge Institute, USC Michelson Center for Convergent Biosciences, University of Southern Califorinia, Los Angeles, CA, USA; Department of Chemistry, University of Southern California, Los Angeles, CA, USA., Han GW; Bridge Institute, USC Michelson Center for Convergent Biosciences, University of Southern Califorinia, Los Angeles, CA, USA; Department of Chemistry, University of Southern California, Los Angeles, CA, USA., Cherezov V; Bridge Institute, USC Michelson Center for Convergent Biosciences, University of Southern Califorinia, Los Angeles, CA, USA; Department of Chemistry, University of Southern California, Los Angeles, CA, USA., Renault N; Univ. Lille, Inserm, U995 - LIRIC - Lille Inflammation Research International Center, ICPAL, 3 rue du Professeur Laguesse, BP-83, F-59006, Lille, France., Barczyk A; Univ. Lille, Inserm, U995 - LIRIC - Lille Inflammation Research International Center, ICPAL, 3 rue du Professeur Laguesse, BP-83, F-59006, Lille, France., Ravez S; Univ. Lille, Inserm, CHU Lille, U1172, LilNCog - Lille Neuroscience & Cognition, F-59000, Lille, France., Coevoet M; Univ. Lille, Inserm, CHU Lille, U1172, LilNCog - Lille Neuroscience & Cognition, F-59000, Lille, France., Melnyk P; Univ. Lille, Inserm, CHU Lille, U1172, LilNCog - Lille Neuroscience & Cognition, F-59000, Lille, France., Liberelle M; Univ. Lille, Inserm, CHU Lille, U1172, LilNCog - Lille Neuroscience & Cognition, F-59000, Lille, France. Electronic address: maxime.liberelle@univ-lille.fr., Yous S; Univ. Lille, Inserm, CHU Lille, U1172, LilNCog - Lille Neuroscience & Cognition, F-59000, Lille, France.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2022 Nov 05; Vol. 241, pp. 114620. Date of Electronic Publication: 2022 Jul 22.

Design, Synthesis and Evaluation of a Series of 1,5-Diaryl-1,2,3-triazole-4-carbohydrazones as Inhibitors of the YAP-TAZ/TEAD Complex.

Autor: Gibault F; INSERM, UMR-S 1172, Lille Neuroscience & Cognition, University of Lille, 59000, Lille, France., Sturbaut M; INSERM, UMR-S 1172, Lille Neuroscience & Cognition, University of Lille, 59000, Lille, France., Coevoet M; INSERM, UMR-S 1172, Lille Neuroscience & Cognition, University of Lille, 59000, Lille, France., Pugnière M; Institut de Recherche en Cancérologie de Montpellier (IRCM), Institut Régional du Cancer de Montpellier (ICM), University of Montpellier, 208 rue des Apothicaires, 34298, Montpellier Cedex 5, France., Burtscher A; Robert J. Tomsich Pathology and Laboratory Medicine Institute and Department of Cancer Biology, Cleveland Clinic, Lerner Research Institute and Taussig Cancer Center, Cleveland, OH 44195, USA., Allemand F; University of Montpellier CNRS UMR5048, INSERM U1054 Centre de Biologie Structurale, 29 rue de Navacelles, 34090, Montpellier, France., Melnyk P; INSERM, UMR-S 1172, Lille Neuroscience & Cognition, University of Lille, 59000, Lille, France., Hong W; Institute of Molecular and Cell Biology, A(✶)STAR, 61 Biopolis Drive, Singapore 138673, Singapore., Rubin BP; Robert J. Tomsich Pathology and Laboratory Medicine Institute and Department of Cancer Biology, Cleveland Clinic, Lerner Research Institute and Taussig Cancer Center, Cleveland, OH 44195, USA., Pobbati AV; Robert J. Tomsich Pathology and Laboratory Medicine Institute and Department of Cancer Biology, Cleveland Clinic, Lerner Research Institute and Taussig Cancer Center, Cleveland, OH 44195, USA., Guichou JF; University of Montpellier CNRS UMR5048, INSERM U1054 Centre de Biologie Structurale, 29 rue de Navacelles, 34090, Montpellier, France., Cotelle P; INSERM, UMR-S 1172, Lille Neuroscience & Cognition, University of Lille, 59000, Lille, France.; Ecole Centrale Lille, 59000, Lille, France., Bailly F; INSERM, UMR-S 1172, Lille Neuroscience & Cognition, University of Lille, 59000, Lille, France.

Publikováno v: ChemMedChem [ChemMedChem] 2021 Sep 16; Vol. 16 (18), pp. 2823-2844. Date of Electronic Publication: 2021 Jul 01.

Prospects for application of high temperature superconductors to electric power networks

Autor: Manuel, P, Camescasse, F.X, Coevoet, M, Leitloff, V, Lesur, F, Serres, E, Suau, P, Muraz, J.A

Publikováno v: In Physica C: Superconductivity and its applications 2002 372 Part 3:1591-1597

Advancements of anticancer agents by targeting the Hippo signalling pathway: biological activity, selectivity, docking analysis, and structure-activity relationship.

Autor: Haripriya E; Integrated Drug Discovery Centre, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, 560107, Karnataka, India., Hemalatha K; Integrated Drug Discovery Centre, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, 560107, Karnataka, India. kamurthy18@gmail.com., Matada GSP; Integrated Drug Discovery Centre, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, 560107, Karnataka, India., Pal R; Integrated Drug Discovery Centre, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, 560107, Karnataka, India. rohitpal.rp096@gmail.com., Das PK; Integrated Drug Discovery Centre, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, 560107, Karnataka, India., Ashadul Sk MD; Integrated Drug Discovery Centre, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, 560107, Karnataka, India., Mounika S; Integrated Drug Discovery Centre, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, 560107, Karnataka, India., Viji MP; Integrated Drug Discovery Centre, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, 560107, Karnataka, India., Aayishamma I; Integrated Drug Discovery Centre, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, 560107, Karnataka, India., Jayashree KR; Integrated Drug Discovery Centre, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, 560107, Karnataka, India.

Publikováno v: Molecular diversity [Mol Divers] 2024 Oct 22. Date of Electronic Publication: 2024 Oct 22.