Aging is associated with reduced inflammatory disease activity independent of disease duration in relapsing multiple sclerosis trial populations.

Autor: Coerver EM; MS Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Location VU Medical Centre, Amsterdam, The Netherlands., Kaçar S; MS Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Location VU Medical Centre, Amsterdam, The Netherlands., Ciccarelli O; Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK.; National Institute for Health and Care Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre, London, UK., Sormani MP; Department of Health Sciences (DISSAL), University of Genova, Genova, Italy; Ospedale Policlinico San Martino IRCCS, Genoa, Italy., Barkhof F; Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK.; Queen Square Institute of Neurology and Centre for Medical Image Computing, University College London, London, UK.; MS Center Amsterdam, Department of Radiology and Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Location VU medical center, Amsterdam, The Netherlands., Arnold DL; Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK.; NeuroRx Research and Montreal Neurological Institute, McGill University, Montreal, QC, Canada.; Montreal Neurological Institute, McConnell Brain Imaging Centre, McGill University, Montreal, QC, Canada., Schoonheim MM; MS Center Amsterdam, Anatomy and Neuroscience, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Location VU medical center, Amsterdam, The Netherlands., Van Kempen ZL; MS Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Location VU Medical Centre, Amsterdam, The Netherlands., Mostert J; Department of Neurology, Rijnstate Hospital, Arnhem, The Netherlands., Koch MW; Department of Clinical Neurosciences, University of Calgary, Calgary, AB, Canada., Killestein J; MS Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Location VU Medical Centre, Amsterdam, The Netherlands., Eshaghi A; Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK.; Queen Square Institute of Neurology and Centre for Medical Image Computing, University College London, London, UK., Uitdehaag BM; MS Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Location VU Medical Centre, Amsterdam, The Netherlands., Strijbis EM; MS Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Location VU Medical Centre, Amsterdam, The Netherlands.

Publikováno v: Multiple sclerosis (Houndmills, Basingstoke, England) [Mult Scler] 2024 Sep; Vol. 30 (10), pp. 1296-1308. Date of Electronic Publication: 2024 Sep 08.