Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Coenraad P. Kuijl"'
Autor:
Ilona van Alen, Mayra A. Aguirre García, Janneke J. Maaskant, Coenraad P. Kuijl, Wilbert Bitter, Annemarie H. Meijer, Marcellus Ubbink
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract The β-lactamase of Mycobacterium tuberculosis, BlaC, hydrolyzes β-lactam antibiotics, hindering the use of these antibiotics for the treatment of tuberculosis. Inhibitors, such as avibactam, can reversibly inhibit the enzyme, allowing for
Externí odkaz:
https://doaj.org/article/a12ee8f2c8fe4e89934290ceb65b2da1
Autor:
Merel P. M. Damen, Aniek S. Meijers, Esther M. Keizer, Sander R. Piersma, Connie R. Jiménez, Coenraad P. Kuijl, Wilbert Bitter, Edith N. G. Houben
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Mycobacteria use specialized type VII secretion systems (T7SSs) to secrete proteins across their diderm cell envelope. One of the T7SS subtypes, named ESX-1, is a major virulence determinant in pathogenic species such as Mycobacterium tuberc
Externí odkaz:
https://doaj.org/article/6d89b33110a1441294f5c9186621cb08
Autor:
Lieve E. H. van der Donk, Jet van der Spek, Tom van Duivenvoorde, Marieke S. ten Brink, Teunis B. H. Geijtenbeek, Coenraad P. Kuijl, Jeroen W. J. van Heijst, Louis S. Ates
Publikováno v:
Biology Open, Vol 11, Iss 2 (2022)
Genetic manipulation of primary lymphocytes is crucial for both clinical purposes and fundamental research. Despite their broad use, we encountered a paucity of data on systematic comparison and optimization of retroviral vectors, the workhorses of g
Externí odkaz:
https://doaj.org/article/c756871783fe4eb685475eb0fd0d363e
Autor:
Lisette Waanders, Lieve E H van der Donk, Louis S Ates, Janneke Maaskant, John L van Hamme, Eric Eldering, Jaco A C van Bruggen, Joanne M Rietveld, Wilbert Bitter, Teunis B H Geijtenbeek, Coenraad P Kuijl
Publikováno v:
Journal for immunotherapy of cancer, 11(4). BioMed Central Ltd.
Waanders, L, van der Donk, L E H, Ates, L S, Maaskant, J, van Hamme, J L, Eldering, E, van Bruggen, J A C, Rietveld, J M, Bitter, W, Geijtenbeek, T B H & Kuijl, C P 2023, ' Ectopic expression of cGAS in Salmonella typhimurium enhances STING-mediated IFN-β response in human macrophages and dendritic cells ', Journal for Immunotherapy of Cancer, vol. 11, no. 4, jitc-2022-005839, pp. 1-13 . https://doi.org/10.1136/jitc-2022-005839
Journal for Immunotherapy of Cancer, 11(4):jitc-2022-005839. BioMed Central
Waanders, L, van der Donk, L E H, Ates, L S, Maaskant, J, van Hamme, J L, Eldering, E, van Bruggen, J A C, Rietveld, J M, Bitter, W, Geijtenbeek, T B H & Kuijl, C P 2023, ' Ectopic expression of cGAS in Salmonella typhimurium enhances STING-mediated IFN-β response in human macrophages and dendritic cells ', Journal for Immunotherapy of Cancer, vol. 11, no. 4, jitc-2022-005839 . https://doi.org/10.1136/jitc-2022-005839
Journal for Immunotherapy of Cancer, 11(4):jitc-2022-005839, 1-13. BioMed Central
Waanders, L, van der Donk, L E H, Ates, L S, Maaskant, J, van Hamme, J L, Eldering, E, van Bruggen, J A C, Rietveld, J M, Bitter, W, Geijtenbeek, T B H & Kuijl, C P 2023, ' Ectopic expression of cGAS in Salmonella typhimurium enhances STING-mediated IFN-β response in human macrophages and dendritic cells ', Journal for Immunotherapy of Cancer, vol. 11, no. 4, jitc-2022-005839, pp. 1-13 . https://doi.org/10.1136/jitc-2022-005839
Journal for Immunotherapy of Cancer, 11(4):jitc-2022-005839. BioMed Central
Waanders, L, van der Donk, L E H, Ates, L S, Maaskant, J, van Hamme, J L, Eldering, E, van Bruggen, J A C, Rietveld, J M, Bitter, W, Geijtenbeek, T B H & Kuijl, C P 2023, ' Ectopic expression of cGAS in Salmonella typhimurium enhances STING-mediated IFN-β response in human macrophages and dendritic cells ', Journal for Immunotherapy of Cancer, vol. 11, no. 4, jitc-2022-005839 . https://doi.org/10.1136/jitc-2022-005839
Journal for Immunotherapy of Cancer, 11(4):jitc-2022-005839, 1-13. BioMed Central
BackgroundInterferon (IFN)-β induction via activation of the stimulator of interferon genes (STING) pathway has shown promising results in tumor models. STING is activated by cyclic dinucleotides such as cyclic GMP–AMP dinucleotides with phosphodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2149b7bf3d883993fac5482fcf45611a
https://pure.amc.nl/en/publications/ectopic-expression-of-cgas-in-salmonella-typhimurium-enhances-stingmediated-ifn-response-in-human-macrophages-and-dendritic-cells(946d907b-8e7c-4291-b92d-ff52383ad71b).html
https://pure.amc.nl/en/publications/ectopic-expression-of-cgas-in-salmonella-typhimurium-enhances-stingmediated-ifn-response-in-human-macrophages-and-dendritic-cells(946d907b-8e7c-4291-b92d-ff52383ad71b).html
The ESX-1 substrate PPE68 has a key function in the ESX-1 mediated secretion inMycobacterium marinum
Autor:
Merel P.M. Damen, Aniek S. Meijers, Esther M. Keizer, Sander R. Piersma, Connie R. Jiménez, Coenraad P. Kuijl, Wilbert Bitter, Edith N. G. Houben
Mycobacteria use specialized type VII secretion systems (T7SSs) to secrete proteins across their diderm cell envelope. One of the T7SS subtypes, named ESX-1, is a major virulence determinant in pathogenic species such asMycobacterium tuberculosisand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a19b6ebcf8f61cc643734f6697251d67
https://doi.org/10.1101/2022.06.21.497121
https://doi.org/10.1101/2022.06.21.497121
Autor:
Eric Eldering, Lisette Waanders, Lieve E H van der Donk, Louis S Ates, Janneke Maaskant, John L van Hamme, Jaco A C van Bruggen, Joanne M Rietveld, Wilbert Bitter, Teunis B H Geijtenbeek, Coenraad P Kuijl
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 4 (2023)
Background Interferon (IFN)-β induction via activation of the stimulator of interferon genes (STING) pathway has shown promising results in tumor models. STING is activated by cyclic dinucleotides such as cyclic GMP–AMP dinucleotides with phosphod
Externí odkaz:
https://doaj.org/article/31940c490bd64fc09c995d4d78516705
Autor:
Louis S Ates, Aniek D van der Woude, Jovanka Bestebroer, Gunny van Stempvoort, René J P Musters, Juan J Garcia-Vallejo, Daisy I Picavet, Robert van de Weerd, Massimiliano Maletta, Coenraad P Kuijl, Nicole N van der Wel, Wilbert Bitter
Publikováno v:
PLoS Pathogens, Vol 12, Iss 6, p e1005696 (2016)
Mycobacteria produce a capsule layer, which consists of glycan-like polysaccharides and a number of specific proteins. In this study, we show that, in slow-growing mycobacteria, the type VII secretion system ESX-5 plays a major role in the integrity
Externí odkaz:
https://doaj.org/article/e7b5acba7b1d4311ab24e3979bb4f3f9