Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Coenraad Hemker"'
Autor:
Evelien Schurgers, Martijn Moorlag, Coenraad Hemker, Theo Lindhout, Hilde Kelchtermans, Bas de Laat
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149135 (2016)
To better understand hypercoagulability as an underlying cause for thrombosis, the leading cause of death in the Western world, new assays to study ex vivo coagulation are essential. The zebrafish is generally accepted as a good model for human hemos
Externí odkaz:
https://doaj.org/article/e088a42a6cee4c41b6746053631bef05
Autor:
Lucia Rugeri, Suzette Beguin, Coenraad Hemker, Jean-Claude Bordet, Raphael Fleury, Brigitte Chatard, Claude Negrier, Yesim Dargaud
Publikováno v:
Haematologica, Vol 92, Iss 12 (2007)
Background and Objectives on Willebrand’s disease (VWD) is the most common hereditary bleeding disorder. Its severity can be classified on the basis of von Willebrand factor (VWF) and factor VIII (FVIII) plasma levels and according to the clinical
Externí odkaz:
https://doaj.org/article/caf80f674a0141cabdcde45ae9888d11
Autor:
Hugo ten Cate, H. Coenraad Hemker
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 8 (2016)
Externí odkaz:
https://doaj.org/article/f83440b293374683bd8bcf34372d7e66
Autor:
H. Coenraad Hemker, Roy Schrijver, Chris P. M. Reutelingsperger, Danielle M. H. Beurskens, Joram Huckriede, Gerry A. F. Nicolaes
Publikováno v:
Thrombosis and Haemostasis. 120:1371-1383
Heparins represent one of the most frequently used pharmacotherapeutics. Discovered around 1926, routine clinical anticoagulant use of heparin was initiated only after the publication of several seminal papers in the early 1970s by the group of Kakka
Autor:
H. Coenraad Hemker, Henri M. H. Spronk, Hugo ten Cate, Yvonne M. C. Henskens, Anne Marije Hulshof
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 2590, p 2590 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 2590, p 2590 (2021)
Fibrinogen is a well-known risk factor for arterial and venous thrombosis. Its function is not restricted to clot formation, however, as it partakes in a complex interplay between thrombin, soluble plasma fibrinogen, and deposited fibrin matrices. Fi
Autor:
Lucyna Mastalerz, Agnieszka Cybulska, Anetta Undas, Coenraad Hemker, Stanisława Bazan-Socha, Pawel Kuczia, Romy Kremers, Daniel P. Potaczek, Lech Zareba
Publikováno v:
Respiratory Medicine, 141, 64-71. Elsevier Saunders
Background: Recently, we have reported that asthma is characterized by prothrombotic blood alterations, which were related to the low-grade inflammatory state. Inflammation, however, may also lead to vascular dysfunction. The aim of this study was to
Autor:
H. Coenraad Hemker, Bas de Laat, Philip G. de Groot, Hilde Kelchtermans, Saartje Bloemen, Romy Kremers, Stéphane Zuily, Denis Wahl, Tessa Peters, Véronique Regnault
Publikováno v:
Blood advances, 2(11), 1315-1324. The American Society of Hematology
Antiphospholipid syndrome (APS) is a condition in which the presence of antibodies against phospholipid-binding proteins is associated with thrombophilia and/or pregnancy morbidity. Although antiphospholipid antibodies have anticoagulant characterist
Publikováno v:
Thrombosis Journal, Vol 16, Iss 1, Pp 1-4 (2018)
Thrombosis Journal, 16:10. BioMed Central Ltd
Thrombosis Journal
Thrombosis Journal, 16:10. BioMed Central Ltd
Thrombosis Journal
Accurate thrombin generation determination by calibrated automated thrombinography can be sustained when reducing the plasma and reagent volumes up to half, but not for higher reductions or plasma dilutions.
Autor:
Agnieszka Cybulska, Grazyna Pulka, Coenraad Hemker, Lucyna Mastalerz, Teresa Iwaniec, Romy Kremers, Jan G. Bazan, Stanisława Bazan-Socha, Anetta Undas, Michal Zabczyk, Lech Zareba
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports
Scientific Reports, 7:11014. Nature Publishing Group
Scientific Reports
Scientific Reports, 7:11014. Nature Publishing Group
Recently we have reported that asthma is associated with enhanced plasma thrombin formation, impaired fibrinolysis and platelet activation. In the present study we investigated whether described prothrombotic blood alterations might predispose to thr
Autor:
Lech Zareba, Anetta Undas, Teresa Iwaniec, Lucyna Mastalerz, Romy Kremers, Michal Zabczyk, Agnieszka Cybulska, Grazyna Pulka, Stanisława Bazan-Socha, Coenraad Hemker
Publikováno v:
Inflammation
Inflammation, 40(4), 1225-1235. Springer
Inflammation, 40(4), 1225-1235. Springer
Recently, we have reported that asthma is associated with enhanced plasma thrombin formation and impaired fibrinolysis. The mechanisms underlying the prothrombotic state in this disease are unknown. Our aim was to investigate whether prothrombotic al