Zobrazeno 1 - 10
of 268
pro vyhledávání: '"Coen A, Stegeman"'
Autor:
Hendrik W. Zijlstra, Gjalt J. Westland, Meint Volbeda, Matijs van Meurs, Janesh Pillay, Casper F. M. Franssen, Coen A. Stegeman, Maarten W. Nijsten
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Whereas urinary creatinine excretion (UCE) is an established marker of muscle mass, both in critically ill and non-critically ill patients, analysis of urinary urea excretion (UUE) may allow estimation of proteolysis that is associated with
Externí odkaz:
https://doaj.org/article/673bae210dbd47beb26f55cc357b1fdb
Autor:
Hendrik W. Zijlstra, Coen A. Stegeman
Publikováno v:
BMC Nephrology, Vol 24, Iss 1, Pp 1-5 (2023)
Abstract Oxalate nephropathy, due to secondary hyperoxaluria has widely been described in gastrointestinal diseases. However, reports of oxalate nephropathy in newly diagnosed celiac disease are rare. A 72-year-old Caucasian male presented to the hos
Externí odkaz:
https://doaj.org/article/182e9853982d4d3f8e6b706554a2b55d
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionImmunoglobulin G (IgG) contains a conserved N-glycan in the fragment crystallizable (Fc), modulating its structure and effector functions. In anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) alterations of IgG Fc-gl
Externí odkaz:
https://doaj.org/article/bac6bdbd6bbd4472a110c6ef734320f7
Autor:
Ietje T. Hazenberg, Stephanie J. M. Middelkoop, Anoek A. E. de Joode, Juliette D. Rabbeljee, Robert A. Pol, Benjamin H. J. Doornweerd, Jan-Stephan F. Sanders, Coen A. Stegeman
Publikováno v:
Frontiers in Nephrology, Vol 3 (2023)
IntroductionUrologic complications (UCs) and urinary tract infections (UTIs) are common after kidney transplantation. Intraoperative stent placement at the vesicoureteric anastomosis reduces UC risk, but increases UTI risk.MethodsIn 2014 our stenting
Externí odkaz:
https://doaj.org/article/8ccbddb167e3434e817a597a81528918
Autor:
Joshua D. Ooi, Jhih-Hang Jiang, Peter J. Eggenhuizen, Ling L. Chua, Mirjan van Timmeren, Khai L. Loh, Kim M. O’Sullivan, Poh Y. Gan, Yong Zhong, Kirill Tsyganov, Lani R. Shochet, Jessica Ryan, Coen A. Stegeman, Lars Fugger, Hugh H. Reid, Jamie Rossjohn, Peter Heeringa, Stephen R. Holdsworth, Anton Y. Peleg, A. Richard Kitching
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Autoreactivity to myeloperoxidase (MPO) causes autoimmune vasculitis and severe glomerulonephritis. Here, Ooi et al. show that a Staphylococcus aureus plasmid encodes a peptide that is homologous to an immunodominant MPO epitope and induces anti-MPO
Externí odkaz:
https://doaj.org/article/ec5422e66a47466790d6d136a48ebe74
Autor:
Adnan Aslan, Marius C. van den Heuvel, Coen A. Stegeman, Eliane R. Popa, Annemarie M. Leliveld, Grietje Molema, Jan G. Zijlstra, Jill Moser, Matijs van Meurs
Publikováno v:
Critical Care, Vol 22, Iss 1, Pp 1-12 (2018)
Abstract Purpose The histopathology of sepsis-associated acute kidney injury (AKI) in critically ill patients remains an understudied area. Previous studies have identified that acute tubular necrosis (ATN) is not the only driver of sepsis-AKI. The f
Externí odkaz:
https://doaj.org/article/c9be856239d0438abbfbe43fc28f8db8
Autor:
Ditmer T. Talsma, Felix Poppelaars, Wendy Dam, Anita H. Meter-Arkema, Romain R. Vivès, Peter Gál, Geert-Jan Boons, Pradeep Chopra, Annamaria Naggi, Marc A. Seelen, Stephan P. Berger, Mohamed R. Daha, Coen A. Stegeman, Jacob van den Born, the COMBAT Consortium
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
It is well-known that heparin and other glycosaminoglycans (GAGs) inhibit complement activation. It is however not known whether fractionation and/or modification of GAGs might deliver pathway-specific inhibition of the complement system. Therefore,
Externí odkaz:
https://doaj.org/article/ab413b7510b74aa8a261d57227ebb687
Autor:
Anouk von Borstel, Wayel H Abdulahad, Gerjan Dekkema, Abraham Rutgers, Coen A Stegeman, Johanna Veldman, Peter Heeringa, Jan Stephan Sanders
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0235743 (2020)
Granulomatosis with polyangiitis (GPA) is an autoimmune disease affecting mainly small blood vessels. B-cells are important in the GPA pathogenesis as precursors of autoantibody-producing cells but likely also contribute (auto)antibody-independently.
Externí odkaz:
https://doaj.org/article/67c7b00a6b624a2eab916a5d1c386563
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-11 (2017)
Abstract Background Persistent expansion of circulating CD4+ effector memory T cells (TEM) in patients with granulomatosis with polyangiitis (GPA) suggests their fundamental role in disease pathogenesis. Recent studies have shown that distinct functi
Externí odkaz:
https://doaj.org/article/6990d348956f4af8a96b6b40f272baa5
Autor:
Gerjan J. Dekkema, Theo Bijma, Pytrick G. Jellema, Anke Van Den Berg, Bart-Jan Kroesen, Coen A. Stegeman, Peter Heeringa, Wayel H. Abdulahad, Jan-Stephan Sanders
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Objectives: Regulatory T cells (Tregs) are frequently functionally impaired in patients with granulomatosis with polyangiitis (GPA). However, the mechanism underlying their impaired function is unknown. Here, we hypothesized that Treg dysfunction in
Externí odkaz:
https://doaj.org/article/04ab150b26d1458fbc16cb8130b2252e