Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Coeli M, Lopes"'
Autor:
Arwa Younis, Christopher Bodurian, Dan E. Arking, Nicola Luigi Bragazzi, Chadi Tabaja, Wojciech Zareba, Scott McNitt, Mehmet K. Aktas, Bronislava Polonsky, Coeli M. Lopes, Nona Sotoodehnia, Peter J. Kudenchuk, Ilan Goldenberg
Publikováno v:
Annals of Noninvasive Electrocardiology, Vol 28, Iss 5, Pp n/a-n/a (2023)
Abstract Background Congenital Long QT Syndrome (LQTS) is a hereditary arrhythmic disorder. We aimed to assess the performance of current genetic variant annotation scores among LQTS patients and their predictive impact. Methods We evaluated 2025 pat
Externí odkaz:
https://doaj.org/article/4e19f24932414ef4aca6d9528dc44de6
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Statins are prescribed for prevention and treatment of coronary artery disease. Statins have different cholesterol lowering abilities, with rosuvastatin and atorvastatin being the most effective, while statins like simvastatin and fluvastatin having
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e81dbaaf86904899d93fae48f5bea6d7
http://link.springer.com/article/10.1038/s41598-019-53700-6
http://link.springer.com/article/10.1038/s41598-019-53700-6
Publikováno v:
Journal of Molecular and Cellular Cardiology. 129:314-325
Statins, in addition to their cholesterol lowering effects, can prevent isoprenylation of Rab GTPase proteins, a key protein family for the regulation of protein trafficking. Rab-GTPases have been shown to be involved in the control of membrane expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdb0f154afec05b14574a55239ecadce
https://doi.org/10.1016/j.yjmcc.2019.03.016
https://doi.org/10.1016/j.yjmcc.2019.03.016
Autor:
Valentina Kutyifa, Anita Y. Chen, Scott McNitt, Spencer Rosero, Christopher G. Scott, Katrina B. Sorensen, Dan E. Arking, Ilan Goldenberg, David T. Huang, Nona Sotoodehnia, Ayhan Yoruk, Mehmet K. Aktas, Michael J. Ackerman, Wojciech Zareba, J. Martijn Bos, Coeli M. Lopes, Kaylie A. Briske, Arwa Younis, Peter J. Kudenchuk, Thomas D. Rea
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background We aimed to provide personalized risk estimates for cardiac events (CEs) and life‐threatening events in women with either type 1 or type 2 long QT. Methods and Results The prognostic model was derived from the Rochester Long QT Syndrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063942ad25b2a11e009581263d40f135
http://europepmc.org/articles/PMC8483453
http://europepmc.org/articles/PMC8483453
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 8, p e0237591 (2020)
PLoS ONE, Vol 15, Iss 8, p e0237591 (2020)
The slow cardiac delayed rectifier current (IKs) is formed by KCNQ1 and KCNE1 subunits and is one of the major repolarizing currents in the heart. Decrease of IKs currents either due to inherited mutations or pathological remodeling is associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32784ec8a5d74395a4648ed756d17c48
http://europepmc.org/articles/PMC7446858
http://europepmc.org/articles/PMC7446858
Autor:
Pornthida Poosala, Douglas M Anderson, Sean Lindley, Xiaorong Xu Parks, Kelly M Anderson, Coeli M. Lopes
Publikováno v:
Circulation Research. 125
Voltage-gated potassium (K + ) channels (VGKCs) are essential regulators of the cardiac action potential and are required to maintain normal heart rhythm and contractility. Voltage-dependent activation, conductance and membrane trafficking of K + cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c30384e0c9b9a1a357757bcfbda5623
https://doi.org/10.1161/res.125.suppl_1.235
https://doi.org/10.1161/res.125.suppl_1.235
Publikováno v:
Journal of molecular and cellular cardiology. 138
The slow voltage-gated potassium channel (IKs) is composed of the KCNQ1 and KCNE1 subunits and is one of the major repolarizing currents in the heart. Activation of protein kinase C (PKC) has been linked to cardiac arrhythmias. Although PKC has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db32de8cb169cfbec496974c2ff220e
https://pubmed.ncbi.nlm.nih.gov/31785237
https://pubmed.ncbi.nlm.nih.gov/31785237
Autor:
Derick R. Peterson, Marielle Alders, Connie R. Bezzina, Wataru Shimizu, Takeshi Aiba, Michael J. Ackerman, Bronislava Polonsky, Coeli M. Lopes, Yoshihiro Miyamoto, Arthur J. Moss, David J. Tester, Jørgen K. Kanters, Carla Spazzolini, Jennifer L. Robinson, Ming Qi, Jeffrey A. Towbin, Arthur A.M. Wilde, Wojciech Zareba, Ilan Goldenberg, Elizabeth S. Kaufman, Jesaia Benhorin, Nynke Hofman, Mark L. Andrews, Lia Crotti, Peter J. Schwartz, Scott McNitt, Shiro Kamakura
Publikováno v:
Circulation, 134(12), 872-882. Lippincott Williams and Wilkins
Circulation 134, 872-882 (2016)
Circulation 134, 872-882 (2016)
Background: Risk stratification in patients with type 3 long-QT syndrome (LQT3) by clinical and genetic characteristics and effectiveness of β-blocker therapy has not been studied previously in a large LQT3 population. Methods: The study population
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c9aa2626fd7ea9277fdd01b340ed43
https://doi.org/10.1161/circulationaha.116.021823
https://doi.org/10.1161/circulationaha.116.021823
Publikováno v:
Journal of molecular and cellular cardiology. 129
Statins, in addition to their cholesterol lowering effects, can prevent isoprenylation of ab GTPase proteins, a key protein family for the regulation of protein trafficking. Rab-GTPases have been shown to be involved in the control of membrane expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c2765dccc8c9b58dd4d315c64b5525c
https://pubmed.ncbi.nlm.nih.gov/30898664
https://pubmed.ncbi.nlm.nih.gov/30898664
Autor:
Chen Braun, Coeli M. Lopes
Publikováno v:
Biophysical Journal. 116:397a-398a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f81fab3ecac954741678aee33bbff3c
https://doi.org/10.1016/j.bpj.2018.11.2149
https://doi.org/10.1016/j.bpj.2018.11.2149