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pro vyhledávání: '"Cody Poe"'
Publikováno v:
BMC Immunology, Vol 20, Iss 1, Pp 1-10 (2019)
Abstract Background T cell activation induces ER stress and upregulates Inositol Requiring Enzyme 1 alpha (IRE1α), an activator of the unfolded protein response (UPR) pathway. Inhibition of IRE1α RNase activity in activated CD4+ splenocytes from na
Externí odkaz:
https://doaj.org/article/62337ecdb27f46328a92b7ea30a5d283
Publikováno v:
BMC Immunology
BMC Immunology, Vol 20, Iss 1, Pp 1-10 (2019)
BMC Immunology, Vol 20, Iss 1, Pp 1-10 (2019)
Background T cell activation induces ER stress and upregulates Inositol Requiring Enzyme 1 alpha (IRE1α), an activator of the unfolded protein response (UPR) pathway. Inhibition of IRE1α RNase activity in activated CD4+ splenocytes from naïve mice
Autor:
Kyeorda Kemp, Cody Poe
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 7, p 1792 (2019)
International Journal of Molecular Sciences, Vol 20, Iss 7, p 1792 (2019)
The unfolded protein response (UPR) is a highly conserved pathway that allows cells to respond to stress in the endoplasmic reticulum caused by an accumulation of misfolded and unfolded protein. This is of great importance to secretory cells because,
Publikováno v:
The Journal of Immunology. 200:110.9-110.9
TH2 cells are crucial in immune responses against extracellular pathogens; however, they can play a predominant role in a number of diseases due to inappropriate IL-4, IL-5, and IL-13 cytokine expression. Therefore, understanding how these cells deve