Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Cody N Heiser"'
Publikováno v:
BMJ Health & Care Informatics, Vol 28, Iss 1 (2021)
Introduction The SARS-CoV-2 (COVID-19) pandemic has exposed health disparities throughout the USA, particularly among racial and ethnic minorities. As a result, there is a need for data-driven approaches to pinpoint the unique constellation of clinic
Externí odkaz:
https://doaj.org/article/5b37fb6cbd5942d1993568601a78fe8a
Autor:
Deronisha Arceneaux, Zhengyi Chen, Alan J. Simmons, Cody N. Heiser, Austin N. Southard-Smith, Michael J. Brenan, Yilin Yang, Bob Chen, Yanwen Xu, Eunyoung Choi, Joshua D. Campbell, Qi Liu, Ken S. Lau
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107242- (2023)
Summary: Droplet-based single-cell RNA-seq (scRNA-seq) data are plagued by ambient contaminations caused by nucleic acid material released by dead and dying cells. This material is mixed into the buffer and is co-encapsulated with cells, leading to a
Externí odkaz:
https://doaj.org/article/023e2b611ee743e9a29a87c90b558a38
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100450- (2021)
Summary: Single-cell RNA sequencing data require several processing procedures to arrive at interpretable results. While commercial platforms can serve as “one-stop shops” for data analysis, they relinquish the flexibility required for customized
Externí odkaz:
https://doaj.org/article/30a75f4ed09e4a2a875ae1bdffa4b74b
Autor:
Cynthia L. Sears, Ken S. Lau, Franck Housseau, Robert J. Coffey, Fengyi Wan, Christian Jobin, Seth T. Walk, Robert A. Anders, Martha J. Shrubsole, Karen Carroll, Patricia Simner, Hua Ding, Shaoguang Wu, Xinqun Wu, Cody N. Heiser, Victoria L. Campodónico, Fuad Mohammad, James R. White, John Michel, Sarah Tomkovich, Christine M. Dejea, Courtney Stevens, Madison McMann, Lana Kim, June L. Chan, Ada J. Tam, Jada C. Domingue, Reece J. Knippel, Nicholas O. Markham, Jie Chen, Julia L. Drewes
Supplementary Figure from Human Colon Cancer–Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c36d44bf3f5e625f3e60e16ee8e663e
https://doi.org/10.1158/2159-8290.22541276
https://doi.org/10.1158/2159-8290.22541276
Autor:
Cynthia L. Sears, Ken S. Lau, Franck Housseau, Robert J. Coffey, Fengyi Wan, Christian Jobin, Seth T. Walk, Robert A. Anders, Martha J. Shrubsole, Karen Carroll, Patricia Simner, Hua Ding, Shaoguang Wu, Xinqun Wu, Cody N. Heiser, Victoria L. Campodónico, Fuad Mohammad, James R. White, John Michel, Sarah Tomkovich, Christine M. Dejea, Courtney Stevens, Madison McMann, Lana Kim, June L. Chan, Ada J. Tam, Jada C. Domingue, Reece J. Knippel, Nicholas O. Markham, Jie Chen, Julia L. Drewes
Supplementary Table from Human Colon Cancer–Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f52ae0bbb8bf1acb1a065acc7498c4
https://doi.org/10.1158/2159-8290.22541270
https://doi.org/10.1158/2159-8290.22541270
Autor:
Cynthia L. Sears, Ken S. Lau, Franck Housseau, Robert J. Coffey, Fengyi Wan, Christian Jobin, Seth T. Walk, Robert A. Anders, Martha J. Shrubsole, Karen Carroll, Patricia Simner, Hua Ding, Shaoguang Wu, Xinqun Wu, Cody N. Heiser, Victoria L. Campodónico, Fuad Mohammad, James R. White, John Michel, Sarah Tomkovich, Christine M. Dejea, Courtney Stevens, Madison McMann, Lana Kim, June L. Chan, Ada J. Tam, Jada C. Domingue, Reece J. Knippel, Nicholas O. Markham, Jie Chen, Julia L. Drewes
Defining the complex role of the microbiome in colorectal cancer and the discovery of novel, protumorigenic microbes are areas of active investigation. In the present study, culturing and reassociation experiments revealed that toxigenic strains of C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b75dc57b0b4d711f49b25e207c8a0afb
https://doi.org/10.1158/2159-8290.c.6549596.v1
https://doi.org/10.1158/2159-8290.c.6549596.v1
Autor:
Cody N. Heiser, Alan J. Simmons, Frank Revetta, Eliot T. McKinley, Marisol A. Ramirez-Solano, Jiawei Wang, Justin Shao, Gregory D. Ayers, Yu Wang, Sarah E. Glass, Harsimran Kaur, Andrea Rolong, Bob Chen, Paige N. Vega, Julia L. Drewes, Nabil Saleh, Simon Vandekar, Angela L. Jones, M. Kay Washington, Joseph T. Roland, Cynthia L. Sears, Qi Liu, Martha J. Shrubsole, Robert J. Coffey, Ken S. Lau
Colorectal cancer exhibits dynamic cellular and genetic heterogeneity during progression from precursor lesions toward malignancy. Leveraging spatial molecular information to construct a phylogeographic map of tumor evolution can reveal individualize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f125eec2cdb2d01b8f5b8cc75194818e
https://doi.org/10.1101/2023.03.09.530832
https://doi.org/10.1101/2023.03.09.530832
Autor:
Harsimran Kaur, Cody N. Heiser, Eliot T. McKinley, Lissa Ventura-Antunes, Coleman R. Harris, Joseph T. Roland, Martha J. Shrubsole, Robert J. Coffey, Ken S. Lau, Simon Vandekar
Spatially resolved molecular assays provide high dimensional genetic, transcriptomic, proteomic, and epigenetic information in situ and at various resolutions. Pairing these data across modalities with histological features enables powerful studies o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68b287371e7c03b0c34982fb6ed4ffb2
https://doi.org/10.1101/2023.02.02.526900
https://doi.org/10.1101/2023.02.02.526900
Autor:
Eliot T. McKinley, Justin Shao, Samuel T. Ellis, Cody N. Heiser, Joseph T. Roland, Mary C. Macedonia, Paige N. Vega, Susie Shin, Robert J. Coffey, Ken S. Lau
Publikováno v:
Cytometry Part A. 101:521-528
Increasingly, highly multiplexed tissue imaging methods are used to profile protein expression at the single-cell level. However, a critical limitation is the lack of robust cell segmentation tools for tissue sections. We present Multiplexed Image Re
Autor:
Jia-Ren Lin, Shu Wang, Shannon Coy, Yu-An Chen, Clarence Yapp, Madison Tyler, Maulik K. Nariya, Cody N. Heiser, Ken S. Lau, Sandro Santagata, Peter K. Sorger
Publikováno v:
Cell
Advanced solid cancers are complex assemblies of tumor, immune, and stromal cells characterized by high intratumoral variation. We use highly multiplexed tissue imaging, 3D reconstruction, spatial statistics, and machine learning to identify cell typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9418a04f7da30349a3fcff8f61873ef
https://europepmc.org/articles/PMC10019067/
https://europepmc.org/articles/PMC10019067/