Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Cody M. Spencer"'
Autor:
Yajun Shou, Ekaterina Koroleva, Cody M. Spencer, Sergey A. Shein, Anna A. Korchagina, Kizil A. Yusoof, Raksha Parthasarathy, Elizabeth A. Leadbetter, Armen N. Akopian, Amanda R. Muñoz, Alexei V. Tumanov
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Lymphotoxin beta receptor (LTβR) is a promising therapeutic target in autoimmune and infectious diseases as well as cancer. Mice with genetic inactivation of LTβR display multiple defects in development and organization of lymphoid organs, mucosal
Externí odkaz:
https://doaj.org/article/c223dc1cf02846ff9d4522e84a2b6a2b
Autor:
Bradley Smith, Xenia L. Schafer, Aslihan Ambeskovic, Cody M. Spencer, Hartmut Land, Joshua Munger
Publikováno v:
Cell Reports, Vol 17, Iss 3, Pp 821-836 (2016)
Metabolic reprogramming is critical to oncogenesis, but the emergence and function of this profound reorganization remain poorly understood. Here we find that cooperating oncogenic mutations drive large-scale metabolic reprogramming, which is both in
Externí odkaz:
https://doaj.org/article/0ac3a35b446149d2b823c22b8fa8151f
Autor:
Sergey A. Shein, Anna A. Korchagina, Alexei V. Tumanov, Raksha Parthasarathy, Elizabeth A. Leadbetter, Kizil A Yusoof, Armen N. Akopian, Cody M. Spencer, Ekaterina P. Koroleva, Yajun Shou, Amanda R. Muñoz
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Lymphotoxin beta receptor (LTβR) is a promising therapeutic target in autoimmune and infectious diseases as well as cancer. Mice with genetic inactivation of LTβR display multiple defects in development and organization of lymphoid organs, mucosal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa4deaf24021ce67cd24d715f2d1f40
https://doi.org/10.3389/fimmu.2021.712632
https://doi.org/10.3389/fimmu.2021.712632
Publikováno v:
Journal of Virology. 89:6406-6417
Oncogenesis is frequently accompanied by the activation of specific metabolic pathways. One such pathway is fatty acid biosynthesis, whose induction is observed upon transformation of a wide variety of cell types. Here, we explored how defined oncoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1064a2fd42d96d24cf4655acf1b0ce9
https://doi.org/10.1128/jvi.03671-14
https://doi.org/10.1128/jvi.03671-14
Autor:
Cody M. Spencer, Sydney Halperin, Alexei V. Tumanov, Ekaterina P. Koroleva, Ekaterina O. Gubernatorova, Elise Macho-Fernandez
Publikováno v:
Journal of Immunological Methods. 421:61-72
Citrobacter rodentium is a natural mouse pathogen which reproducibly infects mice and causes intestinal disease. The C. rodentium model of infection is very useful for investigating host-pathogen immune interactions in the gut, and can also be used t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c2d4f9ef24355b744ad89e68f6458ee
https://doi.org/10.1016/j.jim.2015.02.003
https://doi.org/10.1016/j.jim.2015.02.003
Autor:
Christopher A. Ingraham, Lindsay S. Burwell, Paul S. Brookes, Sergiy M. Nadtochiy, Cody M. Spencer, Alan E. Friedman, Carl A. Pinkert
Publikováno v:
Journal of Molecular and Cellular Cardiology. 46:960-968
The reversible S-nitrosation and inhibition of mitochondrial complex I is a potential mechanism of cardioprotection, recruited by ischemic preconditioning (IPC), S-nitrosothiols, and nitrite. Previously, to exploit this mechanism, the mitochondrial S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0351db4a9a6523c21e07cb7432ec21c7
https://doi.org/10.1016/j.yjmcc.2009.01.012
https://doi.org/10.1016/j.yjmcc.2009.01.012
Autor:
Cody M. Spencer, Scott B. Snapper, Wayne T. Muraoka, Alexei V. Tumanov, Ekaterina P. Koroleva, Ekaterina O. Gubernatorova, Sydney Halperin
Publikováno v:
Inflammatory Bowel Diseases. 22:S3-S4
The balance between immune defense and inflammation in the gut is a highly regulated process that requires interactions between intestinal epithelial cells and the underlying immune system. RORgt+ group 3 innate lymphoid cells (ILC3s) have emerged as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4085775990db6f1ccf2eb4cdd38942f
https://doi.org/10.1097/01.mib.0000480047.19127.68
https://doi.org/10.1097/01.mib.0000480047.19127.68
Autor:
Elise Macho-Fernandez, Michael Tighe, Alexei V. Tumanov, Ekaterina P. Koroleva, Yang Xin Fu, Egídio Torrado, Cody M. Spencer, Andrea M. Cooper
Publikováno v:
Mucosal immunology
The immune mechanisms regulating epithelial cell repair after injury remain poorly defined. We demonstrate here that lymphotoxin beta receptor (LTβR) signaling in intestinal epithelial cells promotes self-repair after mucosal damage. Using a conditi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ba2f91abb37bf80db0c65ffa084217
https://pubmed.ncbi.nlm.nih.gov/25183367
https://pubmed.ncbi.nlm.nih.gov/25183367
Autor:
Elizabeth A. Leadbetter, Cody M. Spencer, Andrea M. Cooper, Jennifer Yates, Marcia A. Blackman, Emilie E. Vomhof-DeKrey
Inflammation is an essential protective part of the body’s response to infection, yet many diseases are the product of inflammation. For example, inflammation can lead to autoimmune disease and tissue damage, and is a key element in chronic health
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::889be87090ecb6e4c7f11092caa9d11d
https://europepmc.org/articles/PMC4311872/
https://europepmc.org/articles/PMC4311872/
We have previously reported that human cytomegalovirus (HCMV) infection induces large-scale changes to host cell glycolytic, nucleic acid, and phospholipid metabolism. Here we explore the viral mechanisms involved in fatty acid biosynthetic activatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b0da46a857d07b3641a8c7b090f46d
https://europepmc.org/articles/PMC3126312/
https://europepmc.org/articles/PMC3126312/