Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Cody M, Rogers"'
Autor:
Clare E. Murray, Anand V. R. Kornepati, Carlos Ontiveros, Yiji Liao, Bárbara de la Peña Avalos, Cody M. Rogers, Zexuan Liu, Yilun Deng, Haiyan Bai, Suresh Kari, Alvaro S. Padron, Jacob T. Boyd, Ryan Reyes, Curtis A. Clark, Robert S. Svatek, Rong Li, Yanfen Hu, Meiling Wang, José R. Conejo-Garcia, Lauren A. Byers, Kavya Ramkumar, Anil K. Sood, Jung-Min Lee, Christin E. Burd, Ratna K. Vadlamudi, Harshita B. Gupta, Weixing Zhao, Eloïse Dray, Patrick Sung, Tyler J. Curiel
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-24 (2024)
Abstract Background Aside from the canonical role of PDL1 as a tumour surface-expressed immune checkpoint molecule, tumour-intrinsic PDL1 signals regulate non-canonical immunopathological pathways mediating treatment resistance whose significance, me
Externí odkaz:
https://doaj.org/article/324b033e9fa34bbcab45721b8054a03a
Autor:
Youngho Kwon, Heike Rösner, Weixing Zhao, Platon Selemenakis, Zhuoling He, Ajinkya S. Kawale, Jeffrey N. Katz, Cody M. Rogers, Francisco E. Neal, Aida Badamchi Shabestari, Valdemaras Petrosius, Akhilesh K. Singh, Marina Z. Joel, Lucy Lu, Stephen P. Holloway, Sandeep Burma, Bipasha Mukherjee, Robert Hromas, Alexander Mazin, Claudia Wiese, Claus S. Sørensen, Patrick Sung
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Exon 27 of the tumor suppressor BRCA2 encodes a portion of the protein crucial for DNA repair, genome maintenance, and tumor suppression. Here the authors show that this domain binds DNA and the RAD51 recombinase to enhance the assembly of RAD51-DNA
Externí odkaz:
https://doaj.org/article/31023ba9447a4531befe74ed9fc6d0e3
Autor:
Cody M. Rogers, Elsbeth Sanders, Phoebe A. Nguyen, Whitney Smith-Kinnaman, Amber L. Mosley, Matthew L. Bochman
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 12, Pp 4347-4357 (2020)
Externí odkaz:
https://doaj.org/article/53176c2ccfd94fbdb3806f6bf9e05a8a
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 12, Pp 4359-4368 (2020)
Externí odkaz:
https://doaj.org/article/8d5a2f62bad94f21b15d0501f4b9da62
Autor:
Anand V.R. Kornepati, Jacob T. Boyd, Clare E. Murray, Julia Saifetiarova, Bárbara de la Peña Avalos, Cody M. Rogers, Haiyan Bai, Alvaro S. Padron, Yiji Liao, Carlos Ontiveros, Robert S. Svatek, Robert Hromas, Rong Li, Yanfen Hu, Jose R. Conejo-Garcia, Ratna K. Vadlamudi, Weixing Zhao, Eloïse Dray, Patrick Sung, Tyler J. Curiel
Publikováno v:
Cancer Res
BRCA1-mediated homologous recombination is an important DNA repair mechanism that is the target of FDA-approved PARP inhibitors, yet details of BRCA1-mediated functions remain to be fully elucidated. Similarly, immune checkpoint molecules are targets
Autor:
Cody M, Rogers, Patrick, Sung
Publikováno v:
Nature structuralmolecular biology. 29(9)
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 12, Pp 4359-4368 (2020)
Most eukaryotic genomes encode multiple RecQ family helicases, including five such enzymes in humans. For many years, the yeast Saccharomyces cerevisiae was considered unusual in that it only contained a single RecQ helicase, named Sgs1. However, it
Autor:
Gabriella E. Fluhler Thornburg, Matthew L. Bochman, Cody M. Rogers, Nicholas J. Buehler, Robert H. Simmons
Publikováno v:
Prog Biophys Mol Biol
DNA inter-strand crosslinks (ICLs) are dangerous lesions that can be caused by a variety of endogenous and exogenous bifunctional compounds. Because covalently linking both strands of the double helix locally disrupts DNA replication and transcriptio
Autor:
Amber L. Mosley, Phoebe A Nguyen, Cody M. Rogers, Whitney R. Smith-Kinnaman, Elsbeth Sanders, Matthew L. Bochman
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 12, Pp 4347-4357 (2020)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
The human genome encodes five RecQ helicases (RECQL1, BLM, WRN, RECQL4, and RECQL5) that participate in various processes underpinning genomic stability. Of these enzymes, the disease-associated RECQL4 is comparatively understudied due to a variety o
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2444
RAD51-mediated homologous recombination (HR) is a conserved mechanism for the repair of DNA double-strand breaks and the maintenance of DNA replication forks. Several breast and ovarian tumor suppressors, including BRCA1 and BARD1, have been implicat