Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Cody Kempen"'
Autor:
Ankita Singh, Michael Beaupre, Cecilia Villegas-Novoa, Kiyoshi Shiomitsu, Stephen J. Gaudino, Suzanne Tawch, Ruhee Damle, Cody Kempen, Biswa Choudhury, Jeremy P. McAleer, Brian S. Sheridan, Paula Denoya, Richard S. Blumberg, Patrick Hearing, Nancy L. Allbritton, Pawan Kumar
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114643- (2024)
Externí odkaz:
https://doaj.org/article/32662145e22e43dabd726659479069cc
Autor:
Stephen J. Gaudino, Ankita Singh, Huakang Huang, Jyothi Padiadpu, Makheni Jean-Pierre, Cody Kempen, Tej Bahadur, Kiyoshi Shiomitsu, Richard Blumberg, Kenneth R. Shroyer, Semir Beyaz, Natalia Shulzhenko, Andrey Morgun, Pawan Kumar
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract IL-22 is critical for ameliorating obesity-induced metabolic disorders. However, it is unknown where IL-22 acts to mediate these outcomes. Here we examine the importance of tissue-specific IL-22RA1 signaling in mediating long-term high fat d
Externí odkaz:
https://doaj.org/article/dff7637b26b44e1ba5afa90bb82f7db3
Autor:
Preet Joshi, Cody Kempen, Stephen J. Gaudino, Onur Eskiocak, Sonika Rathi, Pawan Kumar, Xun Lin, Kenneth R. Shroyer, Neil Mehta, Brian Yueh, Patrick A. McLaughlin, Semir Beyaz, Adrianus W. M. van der Velden, Michael Beaupre, Agnieszka B. Bialkowska, Richard S. Blumberg
Publikováno v:
Mucosal Immunology
Interleukin-22 (IL-22) signaling in the intestines is critical for promoting tissue-protective functions. However, since a diverse array of cell types (absorptive and secretory epithelium as well as stem cells) express IL-22Ra1, a receptor for IL-22,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27343370b62a5de94207b3442893996e
https://doi.org/10.1038/s41385-020-00348-5
https://doi.org/10.1038/s41385-020-00348-5
Autor:
Xun Lin, Stephen J. Gaudino, Kyung Ku Jang, Tej Bahadur, Ankita Singh, Anirban Banerjee, Michael Beaupre, Timothy Chu, Hoi Tong Wong, Chang-Kyung Kim, Cody Kempen, Jordan Axelrad, Huakang Huang, Saba Khalid, Vyom Shah, Onur Eskiocak, Olivia B. Parks, Artan Berisha, Jeremy P. McAleer, Misty Good, Miko Hoshino, Richard Blumberg, Agnieszka B. Bialkowska, Sarah L. Gaffen, Jay K. Kolls, Vincent W. Yang, Semir Beyaz, Ken Cadwell, Pawan Kumar
Publikováno v:
Immunity
The Th17 cell lineage-defining cytokine IL-17A contributes to host defense and inflammatory disease by coordinating multicellular immune responses. The IL-17 receptor (IL-17RA) is expressed by diverse intestinal cell types, and therapies targeting IL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd325755d8dbab484bedca0ec2aae2cf
https://europepmc.org/articles/PMC8895883/
https://europepmc.org/articles/PMC8895883/
Autor:
Preet Joshi, Stephen J. Gaudino, Huakang Huang, Cody Kempen, Makheni Jean-Pierre, Hoi Tong Wong, Pawan Kumar, Michael Beaupre
Publikováno v:
J Immunol
Previous studies indicate that IL-17A plays an important role in mediating the intestinal microbiota and systemic metabolic functions. However, it is not known where IL-17RA signaling occurs to mediate these effects. To investigate this question, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc99b224c71f489e9e125405fbec39c
https://europepmc.org/articles/PMC8556717/
https://europepmc.org/articles/PMC8556717/
Publikováno v:
Inflammatory Bowel Diseases. 28:S18-S18
BACKGROUND IL-17A/F signaling through the IL-17RA/RC receptor complex plays a vital role in immunity and inflammation. The expression of IL-17RA/RC by diverse intestinal epithelial cell types including Paneth cells and the observation that therapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97396b547005755a5d0f4a024df8d5f7
https://doi.org/10.1093/ibd/izac015.027
https://doi.org/10.1093/ibd/izac015.027